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| Short-term perfluorooctane sulfonate exposure impairs Leydig cell regeneration in the adult rat testis via targeting hedgehog signaling 期刊论文
发表期刊: ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY. 出版年: 2021, 卷号: 214
作者: Mao, Baiping; Li, Chao; Wen, Zina; Li, Huitao; Wang, Yiyan; Chen, Lanlan; Lian, Qingquan; Ge, Ren-Shan
  收藏 | 浏览/下载：52/0 | 提交时间：2021/07/30
Leydig cells Leydig cell regeneration Perfluorooctane sulfonate Stem cells Steroidogenesis Hedgehog signaling |
| MDIBL Symposium on Stem Cells and Aging 项目
项目编号: 1R13AG069520-01. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2020-2023
负责人: DRUMMOND, IAIN A. (contact); ROGERS, ARIC N
收藏 | 浏览/下载：50/0 | 提交时间：2021/08/12
Address Age aged Aging Animals Area Atmosphere base Biological Biology Blood Cells Brain Caloric Restriction career Cell Aging Cell Communication cell regeneration Cells Cellular Metabolic Process Collaborations Communities comparative Discipline DNA Damage Engineering Epigenetic Process Equilibrium Faculty Failure Fishes fly Generations Genetic Transcription graduate student Human Immersion Inflammation Inflammatory Injury innovation Island Knowledge Laboratories Longevity Lung Maine Maintenance Medical center meetings Mus Muscle Mutation Natural regeneration novel strategies Organ Organ failure Outcome Pathology Postdoctoral Fellow posters programs regenerative Rejuvenation Research Research Institute Research Personnel research study Scientific Advances and Accomplishments Scientist Series Signal Transduction Skin stem cell niche Stem Cell Research stem cells symposium System The Jackson Laboratory tissue regeneration Tissues tissue stem cells Training |
| Stem Leydig Cells in the Adult Testis: Characterization, Regulation and Potential Applications 期刊论文
发表期刊: ENDOCRINE REVIEWS. 出版年: 2020, 卷号: 41, 期号: 1, 页码: 22-32
作者: Chen, Panpan; Zirkin, Barry R.; Chen, Haolin
收藏 | 浏览/下载：25/0 | 提交时间：2020/05/22
stem Leydig cells steroidogenic stem cells transdifferentiation testosterone hypogonadism transplantation |
| Functionally Distinctive Ptch Receptors Establish Multimodal Hedgehog Signaling in the Tooth Epithelial Stem Cell Niche 期刊论文
发表期刊: STEM CELLS. 出版年: 2019, 卷号: 37, 期号: 9, 页码: 1238-1248
作者: Binder, Martin; Chmielarz, Piotr; Mckinnon, Peter J.; Biggs, Leah C.; Thesleff, Irma; Balic, Anamaria
收藏 | 浏览/下载：29/0 | 提交时间：2019/11/29
Tooth epithelial stem cells Stem cell niche Cervical loop Hedgehog Patched |
| Project 2 - Macrophage regulation of fibrosis and scarring during tissue regeneration 项目
项目编号: 5P20GM104318-08. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: GODWIN, JAMES W
收藏 | 浏览/下载：28/0 | 提交时间：2021/08/12
Address Adult Aging Animal Model Antigens Biological Assay Biological Models Brain Carbohydrates Cell Proliferation cell type Cells cellular targeting Cessation of life Cicatrix Comparative Biology Complex crosslink Development Disease Enzymes Epithelial Epithelial Cells Epithelium Exposure to Extracellular Matrix Fibroblasts Fibrosis Gene Expression Gene Expression Profile Genes Goals healing Healthcare Heart Human human tissue Immune Infection Infiltration Injury Innate Immune System innovation insight Label Laboratories Leukocytes limb amputation limb regeneration Limb structure Liver Lung macrophage Mammals Measures Mediating Mesenchymal Methods Modernization Molecular Myofibroblast Natural regeneration novel Operative Surgical Procedures Organ overexpression Patients Pattern Pharmacology Phenotype Play prevent Process progenitor programs Protein-Lysine 6-Oxidase Proteins PTPRC gene Recovery of Function regenerative regenerative therapy Regulation repaired RNA Interference Role Salamander Signal Pathway Signal Transduction Site Source Spinal Cord Stem cells Surface Testing therapy development Time time use tissue regeneration tissue repair Tissues tool transcriptome sequencing transdifferentiation Traumatic injury wound Wound Healing |
| Project 1 - Disruption of CpG island-mediated gene regulation and chromatin architecture in progeria and aging 项目
项目编号: 5P20GM104318-08. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: BECK, SAMUEL
收藏 | 浏览/下载：25/0 | 提交时间：2021/08/12
Address Age of Onset age related Aging Architecture Atherosclerosis Biological Biology of Aging Biomedical Research Blindness Cardiac Myocytes Cell Differentiation process Cells Chromatin Chromosome Mapping Comparative Biology CpG Islands CRISPR/Cas technology Cytosine Data Set de novo mutation Defect Degenerative Disorder Dinucleoside Phosphates Disease DNA DNA Damage DNA Repair Economics Elements epigenetic regulation Euchromatin Fatty Liver Fluorescent in Situ Hybridization Frequencies Gene Expression Gene Expression Regulation Genes Genetic Genetic Transcription genome editing genome-wide Genomic Instability Goals Guanine Hair Hepatocyte Heterochromatin Impairment induced pluripotent stem cell innovation inorganic phosphate insight Lamin Type A Lamins Life Life Expectancy Link Mediating Meta-Analysis Modeling Molecular Morphology mRNA sequencing Musculoskeletal Mutation Natural regeneration Nuclear Nuclear Lamin Nuclear Lamina Pathology Patients Peripheral Physiological Predisposition prevent Process Progeria promoter Property Proteins Psyche structure Public Health Regulation Resources response restoration Skin Structural Protein Symptoms Testing therapy development tissue repair Tissues Undifferentiated |
| Understanding germ cell pluripotency through an inducible P-granule degradation system 项目
项目编号: 5F32GM128248-02. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2018-2020
负责人: MARNIK, ELISABETH ADKINS
收藏 | 浏览/下载：14/0 | 提交时间：2021/08/12
Adult Animals Auxins base Biological Assay Caenorhabditis elegans Cell Nucleus Cell Proliferation cell type Clustered Regularly Interspaced Short Palindromic Repeats Complex CRISPR/Cas technology Cytoplasm Cytoplasmic Granules Data Development Engineering Exposure to Fertility Generations Genes Germ Germ Cells Goals Human Imagery in vivo Inherited innovation insight Long-Term Effects Malignant Neoplasms Messenger RNA Morphology mRNA Expression mRNA sequencing Muscle Neurites neuronal cell body Neurons Oocytes Organism pluripotency Postdoctoral Fellow premature prevent Process protein degradation Proteins rapid technique regenerative Regulation Reporter Research Research Personnel Ribonucleoproteins RNA Interference safety net sperm cell Stem cells Sterility System Techniques Testing Therapeutic Time Transcript Translations Work young adult |
| Targeting Tumor Oct4 to Deplete Prostate Tumor and Metastasis Initiating Cells. 科技报告
报告编号: AD1049890. 出版年: 2017
作者: Nie, D.
收藏 | 浏览/下载：22/0 | 提交时间：2019/11/30
Prostate cancer Neoplasms Gene expression Genetics Amino acids Cell line Metastasis Epithelial cells Cell nucleus Stem cells Chromosomes Cell physiological processes Therapy Oct4 Cancer stem cells Tumor formation |
| Development of ovarian germline stem cells in Nile tilapia (Oreochromis niloticus) reared under different temperature regimes 学位论文
出版年: 2016
作者: Habibah;Aulidya Nurul
收藏 | 浏览/下载：12/0 | 提交时间：2019/11/29
630 Gonadal development Nile tilapia Elevated temperature Sex determination Temperature Germ line stem cells Vasa PCNA Land- und Forstwirtschaft (PPN621302791) |
| Spheroform: Therapeutic Spheroid-Forming Nanotextured Surfaces Inspired by Desert Beetle Physosterna cribripes 期刊论文
发表期刊: ADVANCED HEALTHCARE MATERIALS. 出版年: 2015, 卷号: 4, 期号: 4, 页码: 511-515
作者: Lee, Mihyun; Yang, Kisuk; Hwang, Yong Hwa; Byun, Youngro; Lee, Dong Yun; Cho, Seung-Woo; Lee, Haeshin
收藏 | 浏览/下载：31/0 | 提交时间：2019/11/29
desert beetles islet cells mesenchymal stem cells polydopamine therapeutic spheroids |
