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Vertebral haemangioma in a Roman period skeleton from the Dakhleh Oasis, Egypt 期刊论文
发表期刊: INTERNATIONAL JOURNAL OF OSTEOARCHAEOLOGY. 出版年: 2020, 卷号: 30, 期号: 4, 页码: 417-424
作者:  Molto, Joseph E.;  Chhem, Rethy;  Maxwell, Jay;  Teeter, Mathew A.;  Sanchez, Jose;  Holdsworth, Dave
收藏  |  浏览/下载:1/0  |  提交时间:2020/05/22
Dakhleh Oasis  haemangioma  human skeleton  microcomputed tomography  palaeoepidemiology  palaeopathology  radiology  vertebra  
Blood-brain barrier genetic disruption leads to protective barrier formation at the Glia Limitans 期刊论文
发表期刊: PLOS BIOLOGY. 出版年: 2020, 卷号: 18, 期号: 11
作者:  Mora, Pierre;  Hollier, Pierre-Louis;  Guimbal, Sarah;  Abelanet, Alice;  Diop, Aissata;  Cornuault, Lauriane;  Couffinhal, Thierry;  Horng, Sam;  Gadeau, Alain-Pierre;  Renault, Marie-Ange;  Chapouly, Candice
收藏  |  浏览/下载:2/0  |  提交时间:2021/01/07
Project 2 - Macrophage regulation of fibrosis and scarring during tissue regeneration 项目
项目编号: 5P20GM104318-08. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2019-
负责人:  GODWIN, JAMES W
收藏  |  浏览/下载:5/0  |  提交时间:2021/08/12
Address  Adult  Aging  Animal Model  Antigens  Biological Assay  Biological Models  Brain  Carbohydrates  Cell Proliferation  cell type  Cells  cellular targeting  Cessation of life  Cicatrix  Comparative Biology  Complex  crosslink  Development  Disease  Enzymes  Epithelial  Epithelial Cells  Epithelium  Exposure to  Extracellular Matrix  Fibroblasts  Fibrosis  Gene Expression  Gene Expression Profile  Genes  Goals  healing  Healthcare  Heart  Human  human tissue  Immune  Infection  Infiltration  Injury  Innate Immune System  innovation  insight  Label  Laboratories  Leukocytes  limb amputation  limb regeneration  Limb structure  Liver  Lung  macrophage  Mammals  Measures  Mediating  Mesenchymal  Methods  Modernization  Molecular  Myofibroblast  Natural regeneration  novel  Operative Surgical Procedures  Organ  overexpression  Patients  Pattern  Pharmacology  Phenotype  Play  prevent  Process  progenitor  programs  Protein-Lysine 6-Oxidase  Proteins  PTPRC gene  Recovery of Function  regenerative  regenerative therapy  Regulation  repaired  RNA Interference  Role  Salamander  Signal Pathway  Signal Transduction  Site  Source  Spinal Cord  Stem cells  Surface  Testing  therapy development  Time  time use  tissue regeneration  tissue repair  Tissues  tool  transcriptome sequencing  transdifferentiation  Traumatic injury  wound  Wound Healing  
Comparative Animal Models (CAM) Core 项目
项目编号: 5P20GM104318-08. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2019-
负责人:  YIN, VIRAVUTH P
收藏  |  浏览/下载:17/0  |  提交时间:2021/08/12
Aging  Animal Husbandry  Animal Model  animal resource  Animals  base  Behavioral  Biological  Biological Models  Biological Process  Biological Sciences  Biology  Caenorhabditis elegans  Cell Line  Centers of Research Excellence  comparative  Comparative Biology  Comparative Study  cost  Cryopreservation  Development  Disease  Drosophila genus  Embryo  Ensure  experimental study  Faculty  Fees  Fees and Charges  Foundations  Funding  Gene Transfer Techniques  Genetic Services  Genotype  Goals  Grant  Heart  Human  human disease  human tissue  Infrastructure  Injury  innovation  insight  International  Invertebrates  Kidney  Knowledge  Laboratories  laboratory curriculum  Lead  Legal patent  Limb structure  Maintenance  Medical  Medicine  member  Methods  Microinjections  Molecular  Mus  Natural regeneration  Organ  Oryziinae  Paper  Patients  Phase  Process  programs  Protocols documentation  Publications  Quarantine  recruit  regenerative  Regenerative Medicine  repaired  Research  research and development  Research Personnel  Research Project Grants  Research Support  Resources  Salamander  Scientist  Services  small molecule  Speed  Spinal Cord  Structure  success  Tissue Harvesting  tissue repair  Tissues  Training Programs  Transgenic Organisms  Translating  Vertebrates  Visit  Visual  Zebrafish  
Optimization of Betulinic Acid analogs for T-type calcium channel inhibition for non-addictive relief of chronic pain 项目
项目编号: 1R41DA050364-01. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2019-2020
负责人:  KHANNA, RAJESH
收藏  |  浏览/下载:14/0  |  提交时间:2021/08/12
Absence of pain sensation  addiction  Affect  Afferent Neurons  American  Amitriptyline  Analgesics  analog  Antidepressive Agents  Arizona  Axon  Baclofen  base  Betulinic Acid  Biological Assay  biophysical properties  Calcium  Calcium Channel Blockers  Calcium Channel Inhibition  cancer pain  Cancer Patient  cancer survival  cancer therapy  Cell-Mediated Cytolysis  Cells  central sensitization  chemotherapeutic agent  chemotherapy  Chemotherapy-induced peripheral neuropathy  Chemotherapy-Oncologic Procedure  Chronic  chronic pain  chronic pain relief  chronic painful condition  Clinical  Clinical Trials  Complex  compliance behavior  Complication  counterscreen  Coupled  design  dorsal horn  Dose-Limiting  drug discovery  Drug Kinetics  Drug Targeting  duloxetine  Dysesthesias  effective therapy  Effectiveness  Esthesia  Feeling  Fiber  G-Protein-Coupled Receptors  Human  improved  In Vitro  in vivo  Indigenous  inhibitor/antagonist  Ion Channel  Laboratories  Lavandula  Lead  Malignant Neoplasms  Mediating  Mediator of activation protein  Medical  Medicinal Plants  meetings  Modeling  Muscle relaxants  Natural Products  Neuraxis  neuronal excitability  Neurons  Neuropathy  neurotoxic  neurotoxicity  neurotransmission  non-opioid analgesic  Norepinephrine  novel  novel therapeutics  Numbness  Opiate Addiction  Opioid  opioid misuse  Opioid Receptor  opioid sparing  opioid use  Oral  Paclitaxel  Pain  Pain management  pain model  pain relief  pain signal  painful neuropathy  Paresthesia  Pathogenesis  Pathway interactions  Peripheral  Peripheral Nerves  Peripheral Nervous System  Peripheral Nervous System Diseases  Pharmaceutical Preparations  Pharmacology  Pharmacotherapy  Phase  Plants  Platinum Compounds  preclinical study  Prevalence  Property  Protein Isoforms  Proteins  Quality of life  Rattus  Regimen  Regulation  reuptake  Role  Safety  screening  Sensory  sensory stimulus  Serotonin  Shock  side effect  Site  small molecule  somatosensory  Southwestern United States  Specificity  Spinal  Spinal Cord  Spinal Ganglia  Structure  success  Survival Rate  synaptic function  T-Type Calcium Channels  taxane  Testing  Tissues  Translating  Treatment Protocols  Universities  venlafaxine  Vinca Alkaloids  voltage  Work  
Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury-associated peripheral sensory neuropathy via block of N- and T-type calcium channels 期刊论文
发表期刊: PAIN. 出版年: 2019, 卷号: 160, 期号: 1, 页码: 117-135
作者:  Bellampalli, Shreya S.;  Ji, Yingshi;  Moutal, Aubin;  Cai, Song;  Wijeratne, E. M. Kithsiri;  Gandini, Maria A.;  Yu, Jie;  Chefdeville, Aude;  Dorame, Angie;  Chew, Lindsey A.;  Madura, Cynthia L.;  Luo, Shizhen;  Molnar, Gabriella;  Khanna, May;  Streicher, John M.;  Zamponi, Gerald W.;  Gunatilaka, A. A. Leslie;  Khanna, Rajesh
收藏  |  浏览/下载:8/0  |  提交时间:2019/11/29
Desert lavender extract  Betulinic acid  T-type calcium channels  Cav3.2/3.3  Nonopioid  HIV-induced sensory neuropathy  Paclitaxel-induced peripheral neuropathy  
Endoplasmic reticulum stress transducer old astrocyte specifically induced substance contributes to astrogliosis after spinal cord injury 期刊论文
发表期刊: NEURAL REGENERATION RESEARCH. 出版年: 2018, 卷号: 13, 期号: 3, 页码: 536-540
作者:  Takazawa, Atsushi;  Kamei, Naosuke;  Adachi, Nobuo;  Ochi, Mitsuo
收藏  |  浏览/下载:2/0  |  提交时间:2019/11/29
unfolded protein response  cAMP-response element binding protein/activating transcription factor protein family  C57BL/6  contusion injury  reactive astrocyte  functional recovery  western blot  real-time polymerase chain reaction  immunohistochemistry  glial fibrillary acidic protein  
The endoplasmic reticulum stress transducer old astrocyte specifically induced substance positively regulates glial scar formation in spinal cord injury 期刊论文
发表期刊: NEUROREPORT. 出版年: 2018, 卷号: 29, 期号: 17, 页码: 1443-1448
作者:  Sumida, Yoshikazu;  Kamei, Naosuke;  Suga, Norifumi;  Ochi, Mitsuo;  Adachi, Nobuo
收藏  |  浏览/下载:3/0  |  提交时间:2019/11/29
astrocyte  astrogliosis  endoplasmic reticulum stress  old astrocyte specifically induced substance  spinal cord injury  
Endoplasmic reticulum stress transducer old astrocyte specifically induced substance contributes to astrogliosis after spinal cord injury 期刊论文
发表期刊: Neural Regeneration Research. 出版年: 2018, 卷号: 13, 期号: 3, 页码: 536-540
作者:  Takazawa Atsushi;  Kamei Naosuke;  Adachi Nobuo;  Ochi Mitsuo
收藏  |  浏览/下载:2/0  |  提交时间:2021/01/08
unfolded protein response  cAMP-response element binding protein/activating transcription factor protein family  C57BL/6  contusion injury  reactive astrocyte  functional recovery  western blot  real-time polymerase chain reaction  immunohistochemistry  glial fibrillary acidic protein  
Validation of locomotion scoring as a new and inexpensive technique to record circadian locomotor activity in large mammals 期刊论文
发表期刊: HELIYON. 出版年: 2018, 卷号: 4, 期号: 12
作者:  Farsi, H.;  Harti, D.;  Achaaban, M. R.;  Piro, M.;  Ouassat, M.;  Challet, E.;  Pevet, P.;  El Allali, K.
收藏  |  浏览/下载:7/0  |  提交时间:2021/01/08
Neuroscience  Physiology