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| Karst geology and mitigation measures for hazards during metro system construction in Wuhan, China 期刊论文
发表期刊: NATURAL HAZARDS. 出版年: 2020, 卷号: 103, 期号: 3, 页码: 2905-2927
作者: Wang, Xiuling; Lai, Jinxing; He, Siyue; Garnes, Rodney Sheldon; Zhang, Yuwei
  收藏 | 浏览/下载：4/0 | 提交时间：2020/08/14
Karst geology Metro tunnel Geologic hazards Prevent and countermeasures Case history |
| Apply an imaging flow cytometry method to screen chemical libraries for identifying and repurposing novel drugs against coccidioidomycosis 项目
项目编号: 1R21AI149015-01. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2020-2021
负责人: HUNG, CHIUNG YU
收藏 | 浏览/下载：6/0 | 提交时间：2021/08/12
acute infection Adverse effects Affect Americas Amphotericin B Animals Antifungal Agents Antimicrobial Resistance Area base Biological Assay Caliber Caspofungin Cell Membrane Permeability Cell Wall Cells chemotherapy Clinical Coccidioides Coccidioides immitis Coccidioides posadasii Coccidioidomycosis Communities Containment Contracts cost Cryptococcus Cryptococcus neoformans Cytochrome P450 Cytology cytotoxicity Data Databases desert fever Development Diagnosis Disease Dose drug development Drug usage drug use screening Flow Cytometry Fluconazole follow-up fungus Goals Government Growth Hand Human Hyphae Image In Vitro in vivo Incubated indexing Infection Inhalation insight Lead Legal patent Libraries Life Cycle Stages Lower respiratory tract structure Lung Lung diseases Medical Medical Research Meningitis Methods Mexico Microscope Morphology Motivation Mycoses Neuraxis novel novel strategies novel therapeutics off-patent pathogen pathogenic fungus Patients Pharmaceutical Preparations Pharmacology Phase IV Clinical Trials Phenotype Pneumonia preclinical development prevent Process Property Reporting Reproduction spores Research Personnel resistant strain Resolution screening small molecule libraries Soil South America Southwestern United States Speed success Symptoms synergism Techniques Testing The science of Mycology Time Toxic effect United States United States National Institutes of Health Vaccines |
| Regulatory T cell function in predicting Valley fever outcomes 项目
项目编号: 1R21AI142261-01A1. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2020-2022
负责人: HOYER, KATRINA K.
收藏 | 浏览/下载：17/0 | 提交时间：2021/08/12
Activities of Daily Living Acute acute infection adaptive immune response Adult Aftercare Age Algorithms Antibiotic Therapy Antifungal Agents Area Arizona Bacterial Infections base Biological Factors Biological Markers Blood California Case Study Cell physiology Cells Cessation of life Child Childhood Chronic Chronic Disease chronic infection Clinic Clinical Coccidioides Coccidioides immitis Coccidioides posadasii Coccidioidomycosis Contracts Data Data Set desert fever Detection Diagnosis Diagnostic Disease Disease Outcome Dust eosinophil Evaluation experience flu Frequencies fungus Health Immune Immune response Immunity Immunologic Factors Immunologic Markers Impaired health improved Incidence Infection Inhalation Knowledge Lung nodule Measurement Methods Mexico Modeling Monitor Mus neutrophil novel older patient Outcome pathogenic fungus Patient Care Patients pediatric patients peripheral blood Pharmaceutical Preparations Phenotype Population prediction algorithm Predictive Factor predictive modeling predictive test prevent Recurrent disease Regulatory T-Lymphocyte Relapse research study Resolution response Severities Severity of illness side effect Soil South America Southwestern United States Symptoms Testing Time tool Translational Research transmission process Travel Vaccines Washington Weather |
| Intracellular Proliferation of the fungal pathogen Histoplasma capsulatum 项目
项目编号: 1R01AI148561-01. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2020-2025
负责人: RAPPLEYE, CHAD A
收藏 | 浏览/下载：21/0 | 提交时间：2021/08/12
Address alpha ketoglutarate Amino Acid Permease Amino Acid Transporter Amino Acids Attenuated base Carbon Catabolism Cells Citric Acid Cycle Coccidioidomycosis Complement Consumption Data desert fever Diagnosis Disease Environment Enzymes Funding Opportunities fungus Genes Genetic Genetic Screening Genetic screening method Genetic Transcription Genus Hippocampus Gluconeogenesis Glutamate Dehydrogenase Glutamates Glycolysis Goals Growth Histoplasma Histoplasma capsulatum Histoplasmosis Immune system Immunocompetent Immunocompromised Host Impairment In Vitro in vivo Individual Infection Innate Immune System interdisciplinary approach Invaded Investigation Isotope Labeling Lung Lung diseases macrophage Measurement Metabolic Metabolic Pathway metabolic profile Metabolism metabolomics Mitochondria Molecular Molecular Biology Molecular Genetics mouse model mutant Mutation Mycoses new therapeutic target novel strategies novel therapeutics Nutrient Nutritional Nutritional Requirements parasitism pathogen Pathogenesis pathogenic fungus Pathway interactions Peptides Phagocytes Phagosomes prevent Proliferating Reaction residence Resources Respiration response RNA Interference Saccharomyces cerevisiae Source Substrate Specificity Systemic disease Testing Therapeutic Time transcriptomics uptake Virulence Yeasts |
| Project 1 - Environmental Project 1 - EP1 - Immobilization of U, As, and Co-occurring Metals in Mine Wastes 项目
项目编号: 5P42ES025589-04. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: CERRATO, JOSE MANUEL
收藏 | 浏览/下载：4/0 | 提交时间：2021/08/12
Address Adsorption Aerobic Affect Amendment aqueous Basic Science bioaccumulation Biological Carbonates Characteristics Chemicals Chemistry Climate Climate Controls Collaborations Communities Complement contaminated drinking water cultural values Custom Decision Making Desert Climate Development Ecology Engineering Environment Environmental Engineering technology Environmental Microbiology experience experimental study Exposure to Exudate Geographic Factor Goals Hazardous Substances Hazardous Waste Sites Health Home environment Human IGFBP2 gene Immobilization In Vitro Individual Ingestion innovation inorganic phosphate interfacial Intervention iron oxide Knowledge Laboratories Ligands mathematical model Measures member metagenome Metal exposure metal poisoning Metals Methods microbiome microbiome alteration microorganism Microscopy migration Minerals Mining Modeling Molecular Native Americans Navajo New Mexico next generation sequencing Outcomes Research Oxides Pattern Phase Pilot Projects Plant Roots Plants Play Population Precipitation prevent Process programs Pueblo Race Rain Reaction remediation Research Resources Risk Risk Reduction Role Sampling Science Scientist Seasons Site Soil Source Spectrum Analysis Superfund Surface System Techniques Testing tool Toxic effect toxic metal tribal community tribal lands Tribes Underserved Population Universities uptake Uranium wasting Water water flow |
| Project 2 - Macrophage regulation of fibrosis and scarring during tissue regeneration 项目
项目编号: 5P20GM104318-08. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: GODWIN, JAMES W
收藏 | 浏览/下载：5/0 | 提交时间：2021/08/12
Address Adult Aging Animal Model Antigens Biological Assay Biological Models Brain Carbohydrates Cell Proliferation cell type Cells cellular targeting Cessation of life Cicatrix Comparative Biology Complex crosslink Development Disease Enzymes Epithelial Epithelial Cells Epithelium Exposure to Extracellular Matrix Fibroblasts Fibrosis Gene Expression Gene Expression Profile Genes Goals healing Healthcare Heart Human human tissue Immune Infection Infiltration Injury Innate Immune System innovation insight Label Laboratories Leukocytes limb amputation limb regeneration Limb structure Liver Lung macrophage Mammals Measures Mediating Mesenchymal Methods Modernization Molecular Myofibroblast Natural regeneration novel Operative Surgical Procedures Organ overexpression Patients Pattern Pharmacology Phenotype Play prevent Process progenitor programs Protein-Lysine 6-Oxidase Proteins PTPRC gene Recovery of Function regenerative regenerative therapy Regulation repaired RNA Interference Role Salamander Signal Pathway Signal Transduction Site Source Spinal Cord Stem cells Surface Testing therapy development Time time use tissue regeneration tissue repair Tissues tool transcriptome sequencing transdifferentiation Traumatic injury wound Wound Healing |
| Project 1 - Disruption of CpG island-mediated gene regulation and chromatin architecture in progeria and aging 项目
项目编号: 5P20GM104318-08. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: BECK, SAMUEL
收藏 | 浏览/下载：5/0 | 提交时间：2021/08/12
Address Age of Onset age related Aging Architecture Atherosclerosis Biological Biology of Aging Biomedical Research Blindness Cardiac Myocytes Cell Differentiation process Cells Chromatin Chromosome Mapping Comparative Biology CpG Islands CRISPR/Cas technology Cytosine Data Set de novo mutation Defect Degenerative Disorder Dinucleoside Phosphates Disease DNA DNA Damage DNA Repair Economics Elements epigenetic regulation Euchromatin Fatty Liver Fluorescent in Situ Hybridization Frequencies Gene Expression Gene Expression Regulation Genes Genetic Genetic Transcription genome editing genome-wide Genomic Instability Goals Guanine Hair Hepatocyte Heterochromatin Impairment induced pluripotent stem cell innovation inorganic phosphate insight Lamin Type A Lamins Life Life Expectancy Link Mediating Meta-Analysis Modeling Molecular Morphology mRNA sequencing Musculoskeletal Mutation Natural regeneration Nuclear Nuclear Lamin Nuclear Lamina Pathology Patients Peripheral Physiological Predisposition prevent Process Progeria promoter Property Proteins Psyche structure Public Health Regulation Resources response restoration Skin Structural Protein Symptoms Testing therapy development tissue repair Tissues Undifferentiated |
| Project 3 - Defining the role of ribosome protein composition in regulating the selective translation of pro-longevity genes 项目
项目编号: 5P20GM104318-08. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: ROLLINS, JAROD ALTON
收藏 | 浏览/下载：3/0 | 提交时间：2021/08/12
Address Adult Affect Age age related Aging aging gene Animal Model Animals Biology of Aging Caenorhabditis elegans Caloric Restriction Cardiovascular Diseases Chronic Comparative Biology Cost of Illness CRISPR/Cas technology Data Databases Development differential expression Disease Drosophila genus Exposure to Gene Expression Genes Genetic genetic manipulation Genetic Models Genetic Transcription Genetic Translation Genome engineering Goals Health Health Expenditures healthy aging High-Throughput RNA Sequencing Human innovation insight Invertebrates knock-down Life Longevity longevity gene Malignant Neoplasms Mass Spectrum Analysis Mediating Messenger RNA middle age Molecular Molecular Machines mRNA sequencing Mus Natural regeneration Nerve Degeneration novel overexpression Pathway interactions Pharmacologic Substance Polyribosomes polysome profiling prevent Process Proteins Proteomics Ribosomal Proteins Ribosomes Risk Factors RNA Interference Role stressor Testing therapy development Time tissue repair Transcript transcriptomics Translating Translations Vertebrates Yeasts |
| Evaluating an Online Adjunctive Support following Intensive Services (OASIS) Strategy for Youth with Selective Mutism 项目
项目编号: 1F31MH122101-01. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-2021
负责人: HONG, NATALIE
收藏 | 浏览/下载：4/0 | 提交时间：2021/08/12
Acute Anxiety Disorders barrier to care base Behavior Therapy career Caring Child Childhood Clinical Clinical Trials Communities community setting Complex design Development Disease remission evidence base Evidence based treatment experience Failure Family Fellowship follow-up Fostering Geography Goals Grant Health Personnel Healthcare Home environment Impairment improved improved outcome Individual innovation Intensive Care Intervention Investigational Therapies Knowledge Lead Linguistics literacy Logistics Maintenance Mental Health Methodology Modernization novel Outcome personalized intervention Population pre-doctoral Predictive Factor prevent programs Psychological reinforcement Psychopathology Randomized Randomized Controlled Trials Relapse Reporting Research Sampling Schools Science Selection for Treatments Services Severities skill acquisition skills social social situation sociodemographics success symptom treatment Symptoms Technology telehealth Time Training Transcend Treatment outcome treatment planning treatment program treatment responders treatment strategy trend Videoconferencing Voluntary Mutism Work Youth |
| Project 1 - Environmental Project 1 - EP1 - Immobilization of U, As, and Co-occurring Metals in Mine Wastes 项目
项目编号: 5P42ES025589-02. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2018-
负责人: CERRATO, JOSE MANUEL
收藏 | 浏览/下载：3/0 | 提交时间：2021/08/12
Address Adsorption Aerobic Affect Amendment aqueous Basic Science bioaccumulation Biological Carbonates Characteristics Chemicals Chemistry Climate Climate Controls Collaborations Communities Complement contaminated drinking water cultural values Custom Decision Making Desert Climate Development Ecology Engineering Environment Environmental Engineering technology Environmental Microbiology experience experimental study Exposure to Exudate Geographic Factor Goals Hazardous Substances Hazardous Waste Sites Health Home environment Human IGFBP2 gene Immobilization In Vitro Individual Ingestion innovation inorganic phosphate interfacial Intervention Knowledge Laboratories Ligands mathematical model Measures member metagenome Metal exposure metal poisoning Metals Methods microbiome microbiome alteration microorganism Microscopy migration Minerals Mining Modeling Molecular Native Americans Navajo New Mexico next generation sequencing Outcomes Research Oxides Pattern Phase Pilot Projects Plant Roots Plants Play Population Precipitation prevent Process programs Pueblo Race Rain Reaction remediation Research Resources Risk Risk Reduction Role Sampling Science Scientist Seasons Site Soil Source Spectrum Analysis Superfund Surface System Techniques Testing tool Toxic effect toxic metal tribal community tribal lands Tribes Underserved Population Universities uptake Uranium wasting Water water flow |
