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| Highly sex specific gene expression in Jojoba 期刊论文 发表期刊: BMC PLANT BIOLOGY. 出版年: 2023, 卷号: 23, 期号: 1 作者: Alsubaie, Bader; Kharabian-Masouleh, Ardashir; Furtado, Agnelo; Al-Dossary, Othman; Al-Mssallem, Ibrahim; Henry, Robert J.
 收藏  |  浏览/下载:23/0  |  提交时间:2024/09/29 Jojoba Chromosomes Differentially expressed genes RNA-Seq Flower Novel genes Dioecious plants Simmondsia chinensis |
| The Immense Functional Attributes of Maize Rhizosphere Microbiome: A Shotgun Sequencing Approach 期刊论文 发表期刊: AGRICULTURE-BASEL. 出版年: 2021, 卷号: 11, 期号: 2 作者: Akinola, Saheed Adekunle; Ayangbenro, Ayansina Segun; Babalola, Olubukola Oluranti
 收藏  |  浏览/下载:43/0  |  提交时间:2021/07/30 food safety high-throughput metagenomics microbial functional distinctiveness novel genes soil stressors sustainable agriculture |
| Systems-level genetic patterns underlying disseminated coccidioidomycosis in humans 项目 项目编号: 1R21AI152394-01. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2020-2022 负责人: LUSSIER, YVES A.
 收藏  |  浏览/下载:36/0  |  提交时间:2021/08/12 Acute Address adverse outcome African American Alleles Automobile Driving Biochemical Biological Biological Process Biology bone Brain Candidate Disease Gene Caring Case Study Categories causal variant Chronic Clinical clinical care Coccidioides Coccidioidomycosis Code cohort Communicable Diseases Complex Data Databases desert fever design Disease Disease susceptibility DNA Emerging Communicable Diseases Equilibrium Exogenous Factors exome exome sequencing experience Filipino flu Foundations fungus Gene Expression Gene Mutation Genes Genetic genetic architecture Genetic Heterogeneity Genetic Predisposition to Disease genetic risk factor Genetic Variation genome-wide genome-wide analysis Genotype genotyped patients Guidelines Haplotypes Heterogeneity high risk HLA Antigens Human Human Genetics human leukocyte antigen testing IFNGR1 gene IL12RB1 gene Immune Immune response Immune system Immunocompetent Immunogenetics Immunological Models Immunosuppression Infection Inhalation insight Knowledge Life Lung Medical Modeling Molecular Mutation Mycoses National Institute of Allergy and Infectious Disease novel Organ Participant pathogen pathogen exposure Pathogenesis pathogenic fungus Pathology Pathway Analysis Pathway interactions Patients Pattern Phenotype Play Pneumonia Positioning Attribute Predisposition Proteins Quantitative Trait Loci rare variant Recommendation recruit Resistance Resources response Risk risk variant Role Sample Size Sampling Studies Signal Transduction Skin Soil STAT1 gene STAT3 gene Stimulus Symptoms System Systems Analysis Testing Therapeutic Time Variant whole genome |
| Intracellular Proliferation of the fungal pathogen Histoplasma capsulatum 项目 项目编号: 1R01AI148561-01. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2020-2025 负责人: RAPPLEYE, CHAD A
 收藏  |  浏览/下载:51/0  |  提交时间:2021/08/12 Address alpha ketoglutarate Amino Acid Permease Amino Acid Transporter Amino Acids Attenuated base Carbon Catabolism Cells Citric Acid Cycle Coccidioidomycosis Complement Consumption Data desert fever Diagnosis Disease Environment Enzymes Funding Opportunities fungus Genes Genetic Genetic Screening Genetic screening method Genetic Transcription Genus Hippocampus Gluconeogenesis Glutamate Dehydrogenase Glutamates Glycolysis Goals Growth Histoplasma Histoplasma capsulatum Histoplasmosis Immune system Immunocompetent Immunocompromised Host Impairment In Vitro in vivo Individual Infection Innate Immune System interdisciplinary approach Invaded Investigation Isotope Labeling Lung Lung diseases macrophage Measurement Metabolic Metabolic Pathway metabolic profile Metabolism metabolomics Mitochondria Molecular Molecular Biology Molecular Genetics mouse model mutant Mutation Mycoses new therapeutic target novel strategies novel therapeutics Nutrient Nutritional Nutritional Requirements parasitism pathogen Pathogenesis pathogenic fungus Pathway interactions Peptides Phagocytes Phagosomes prevent Proliferating Reaction residence Resources Respiration response RNA Interference Saccharomyces cerevisiae Source Substrate Specificity Systemic disease Testing Therapeutic Time transcriptomics uptake Virulence Yeasts |
| Splice modulatory therapy for valley fever 项目 项目编号: 1R21AI154106-01. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2020-2022 负责人: BURKART, MICHAEL D.
 收藏  |  浏览/下载:34/0  |  提交时间:2021/08/12 Acute Myelocytic Leukemia Amphotericin B analog anti-cancer Antifungal Agents Arizona Azoles base Biological Biological Markers Biology California cancer cell Cells Chemicals Clinical Coccidioides immitis Coccidioides posadasii Coccidioidomycosis combat Communities desert fever design Development Diagnosis Disease Drug Interactions Dust Evaluation Event Family flu Fluconazole Funding fungus Future Genes Goals high reward high risk Human Incidence Individual Infection Investigation Laboratories Lead Left Life Messenger RNA Modernization Natural Products new therapeutic target next generation novel Oncogenic Outcome outcome forecast Pathway interactions Patients Pattern Pharmaceutical Chemistry Pharmaceutical Preparations Play Pneumonia Positioning Attribute Precipitation preclinical study Preparation programs Reporting RNA Splicing scaffold Seasons Series Side side effect small molecule Spliceosomes Structure System Systems Biology Techniques Testing Therapeutic therapeutic target tool transcriptome transcriptomics Translating Translations United States Work |
| Project 2 - Macrophage regulation of fibrosis and scarring during tissue regeneration 项目 项目编号: 5P20GM104318-08. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2019- 负责人: GODWIN, JAMES W
 收藏  |  浏览/下载:38/0  |  提交时间:2021/08/12 Address Adult Aging Animal Model Antigens Biological Assay Biological Models Brain Carbohydrates Cell Proliferation cell type Cells cellular targeting Cessation of life Cicatrix Comparative Biology Complex crosslink Development Disease Enzymes Epithelial Epithelial Cells Epithelium Exposure to Extracellular Matrix Fibroblasts Fibrosis Gene Expression Gene Expression Profile Genes Goals healing Healthcare Heart Human human tissue Immune Infection Infiltration Injury Innate Immune System innovation insight Label Laboratories Leukocytes limb amputation limb regeneration Limb structure Liver Lung macrophage Mammals Measures Mediating Mesenchymal Methods Modernization Molecular Myofibroblast Natural regeneration novel Operative Surgical Procedures Organ overexpression Patients Pattern Pharmacology Phenotype Play prevent Process progenitor programs Protein-Lysine 6-Oxidase Proteins PTPRC gene Recovery of Function regenerative regenerative therapy Regulation repaired RNA Interference Role Salamander Signal Pathway Signal Transduction Site Source Spinal Cord Stem cells Surface Testing therapy development Time time use tissue regeneration tissue repair Tissues tool transcriptome sequencing transdifferentiation Traumatic injury wound Wound Healing |
| Project 3 - Defining the role of ribosome protein composition in regulating the selective translation of pro-longevity genes 项目 项目编号: 5P20GM104318-08. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2019- 负责人: ROLLINS, JAROD ALTON
 收藏  |  浏览/下载:31/0  |  提交时间:2021/08/12 Address Adult Affect Age age related Aging aging gene Animal Model Animals Biology of Aging Caenorhabditis elegans Caloric Restriction Cardiovascular Diseases Chronic Comparative Biology Cost of Illness CRISPR/Cas technology Data Databases Development differential expression Disease Drosophila genus Exposure to Gene Expression Genes Genetic genetic manipulation Genetic Models Genetic Transcription Genetic Translation Genome engineering Goals Health Health Expenditures healthy aging High-Throughput RNA Sequencing Human innovation insight Invertebrates knock-down Life Longevity longevity gene Malignant Neoplasms Mass Spectrum Analysis Mediating Messenger RNA middle age Molecular Molecular Machines mRNA sequencing Mus Natural regeneration Nerve Degeneration novel overexpression Pathway interactions Pharmacologic Substance Polyribosomes polysome profiling prevent Process Proteins Proteomics Ribosomal Proteins Ribosomes Risk Factors RNA Interference Role stressor Testing therapy development Time tissue repair Transcript transcriptomics Translating Translations Vertebrates Yeasts |
| Deciphering the metagenome-encoded pathway and domain structure for Palmerolide biosynthesis 项目 项目编号: 5R21CA205932-02. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2018-2020 负责人: BAKER, BILL J; CHAIN, PATRICK S. G.; MURRAY, ALISON ELIZABETH (contact)
 收藏  |  浏览/下载:28/0  |  提交时间:2021/08/12 3-hydroxy-3-methylglutaryl-coenzyme A Anabolism Antarctic Architecture ascidian Atmosphere Bacteria Bacterial Genome base Base Sequence Bioinformatics cancer therapy candidate validation cell growth Cell Line cell type Cells chemotherapeutic agent chemotherapy Clinical Code contig Cytostatics cytotoxicity Data Development Diagnosis Disease drug development Drug Targeting fighting Gene Cluster Genes genetic manipulation Genome Genome Mappings genome sequencing Genomics Goals Harvest High-Risk Cancer Human Cell Line Hybrids Immunotherapy In Vitro indexing insight interest Ligase Macrolides Marines markov model Melanins melanocyte melanoma Melanoma Cell metagenome metagenomic sequencing Metastatic Melanoma microbial microbiome microorganism Mining Modeling Molecular Mutagenesis Natural Products New Agents next generation novel Organism Outcomes Research Pathway interactions peptide synthase Pharmaceutical Preparations Pharmacology polyketide synthase Preparation Procedures Production Proton Pump reference genome Research research and development Resistance Resistance development Ribosomal RNA Risk scale up screening Signal Transduction Pathway Skin Skin Cancer Source Specificity Specimen stratospheric ozone Structure Survival Rate symbiont System targeted agent Therapeutic tool Toxic effect Treatment Efficacy tumor Ultraviolet Rays United States vacuolar H+-ATPase whole genome |