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| Systems-level genetic patterns underlying disseminated coccidioidomycosis in humans 项目
项目编号: 1R21AI152394-01. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2020-2022
负责人: LUSSIER, YVES A.
  收藏 | 浏览/下载：36/0 | 提交时间：2021/08/12
Acute Address adverse outcome African American Alleles Automobile Driving Biochemical Biological Biological Process Biology bone Brain Candidate Disease Gene Caring Case Study Categories causal variant Chronic Clinical clinical care Coccidioides Coccidioidomycosis Code cohort Communicable Diseases Complex Data Databases desert fever design Disease Disease susceptibility DNA Emerging Communicable Diseases Equilibrium Exogenous Factors exome exome sequencing experience Filipino flu Foundations fungus Gene Expression Gene Mutation Genes Genetic genetic architecture Genetic Heterogeneity Genetic Predisposition to Disease genetic risk factor Genetic Variation genome-wide genome-wide analysis Genotype genotyped patients Guidelines Haplotypes Heterogeneity high risk HLA Antigens Human Human Genetics human leukocyte antigen testing IFNGR1 gene IL12RB1 gene Immune Immune response Immune system Immunocompetent Immunogenetics Immunological Models Immunosuppression Infection Inhalation insight Knowledge Life Lung Medical Modeling Molecular Mutation Mycoses National Institute of Allergy and Infectious Disease novel Organ Participant pathogen pathogen exposure Pathogenesis pathogenic fungus Pathology Pathway Analysis Pathway interactions Patients Pattern Phenotype Play Pneumonia Positioning Attribute Predisposition Proteins Quantitative Trait Loci rare variant Recommendation recruit Resistance Resources response Risk risk variant Role Sample Size Sampling Studies Signal Transduction Skin Soil STAT1 gene STAT3 gene Stimulus Symptoms System Systems Analysis Testing Therapeutic Time Variant whole genome |
| Understanding the natural Coccidioides bioaerosol in time and space and its relationship to disease 项目
项目编号: 1R21AI149660-01. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2020-2022
负责人: ENGELTHALER, DAVID M
收藏 | 浏览/下载：35/0 | 提交时间：2021/08/12
Address Aerosols Affect Air air filter air sampling Animals Area beta diversity Biological Assay Canis familiaris Climate climate change Coccidioides Coccidioidomycosis Collection Communities Community Health Data desert fever Detection Development Disease disease natural history disorder risk DNA Dust Ecology Environment Environmental Monitoring Environmental Risk Factor Environmental Wind epidemiologic data Epidemiology Event exposed human population Exposure to Fungal DNA Fungal Spores fungus Genomics Health Health Care Costs healthcare community Human Human Activities Humidity Incidence Infection Inhalation Knowledge knowledge base Locales Location Meteorology metropolitan microbiome analysis Modeling Monitor Morbidity - disease rate Movement Multivariate Analysis mycobiome Nature novel strategies Outcome Particulate Matter pathogen pathogenic fungus Pattern Population Precipitation predictive modeling Prevalence process optimization prospective Public Health Recreation Research Research Personnel Risk Risk Factors risk mitigation Schools severe weather Site Soil Source Southwestern United States Spatial Distribution suburb System Temperature The science of Mycology Time Veterinarians Weather whole genome Work Workplace |
| Regulatory T cell function in predicting Valley fever outcomes 项目
项目编号: 1R21AI142261-01A1. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2020-2022
负责人: HOYER, KATRINA K.
收藏 | 浏览/下载：51/0 | 提交时间：2021/08/12
Activities of Daily Living Acute acute infection adaptive immune response Adult Aftercare Age Algorithms Antibiotic Therapy Antifungal Agents Area Arizona Bacterial Infections base Biological Factors Biological Markers Blood California Case Study Cell physiology Cells Cessation of life Child Childhood Chronic Chronic Disease chronic infection Clinic Clinical Coccidioides Coccidioides immitis Coccidioides posadasii Coccidioidomycosis Contracts Data Data Set desert fever Detection Diagnosis Diagnostic Disease Disease Outcome Dust eosinophil Evaluation experience flu Frequencies fungus Health Immune Immune response Immunity Immunologic Factors Immunologic Markers Impaired health improved Incidence Infection Inhalation Knowledge Lung nodule Measurement Methods Mexico Modeling Monitor Mus neutrophil novel older patient Outcome pathogenic fungus Patient Care Patients pediatric patients peripheral blood Pharmaceutical Preparations Phenotype Population prediction algorithm Predictive Factor predictive modeling predictive test prevent Recurrent disease Regulatory T-Lymphocyte Relapse research study Resolution response Severities Severity of illness side effect Soil South America Southwestern United States Symptoms Testing Time tool Translational Research transmission process Travel Vaccines Washington Weather |
| Splice modulatory therapy for valley fever 项目
项目编号: 1R21AI154106-01. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2020-2022
负责人: BURKART, MICHAEL D.
收藏 | 浏览/下载：35/0 | 提交时间：2021/08/12
Acute Myelocytic Leukemia Amphotericin B analog anti-cancer Antifungal Agents Arizona Azoles base Biological Biological Markers Biology California cancer cell Cells Chemicals Clinical Coccidioides immitis Coccidioides posadasii Coccidioidomycosis combat Communities desert fever design Development Diagnosis Disease Drug Interactions Dust Evaluation Event Family flu Fluconazole Funding fungus Future Genes Goals high reward high risk Human Incidence Individual Infection Investigation Laboratories Lead Left Life Messenger RNA Modernization Natural Products new therapeutic target next generation novel Oncogenic Outcome outcome forecast Pathway interactions Patients Pattern Pharmaceutical Chemistry Pharmaceutical Preparations Play Pneumonia Positioning Attribute Precipitation preclinical study Preparation programs Reporting RNA Splicing scaffold Seasons Series Side side effect small molecule Spliceosomes Structure System Systems Biology Techniques Testing Therapeutic therapeutic target tool transcriptome transcriptomics Translating Translations United States Work |
| Evaluating an Online Adjunctive Support following Intensive Services (OASIS) Strategy for Youth with Selective Mutism 项目
项目编号: 1F31MH122101-01. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-2021
负责人: HONG, NATALIE
收藏 | 浏览/下载：31/0 | 提交时间：2021/08/12
Acute Anxiety Disorders barrier to care base Behavior Therapy career Caring Child Childhood Clinical Clinical Trials Communities community setting Complex design Development Disease remission evidence base Evidence based treatment experience Failure Family Fellowship follow-up Fostering Geography Goals Grant Health Personnel Healthcare Home environment Impairment improved improved outcome Individual innovation Intensive Care Intervention Investigational Therapies Knowledge Lead Linguistics literacy Logistics Maintenance Mental Health Methodology Modernization novel Outcome personalized intervention Population pre-doctoral Predictive Factor prevent programs Psychological reinforcement Psychopathology Randomized Randomized Controlled Trials Relapse Reporting Research Sampling Schools Science Selection for Treatments Services Severities skill acquisition skills social social situation sociodemographics success symptom treatment Symptoms Technology telehealth Time Training Transcend Treatment outcome treatment planning treatment program treatment responders treatment strategy trend Videoconferencing Voluntary Mutism Work Youth |
| Role of NRF2 in the Pulmonary Response to Inhaled Mine Tailing Dust 项目
项目编号: 5P42ES004940-29. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2018-
负责人: ZHANG, DONNA D
收藏 | 浏览/下载：38/0 | 提交时间：2021/08/12
Adverse effects Affect airway epithelium Alveolar Arsenic Autophagocytosis base Binding Biological Assay Biological Markers Bronchiectasis Butter Carcinogens Cells Chemopreventive Agent Chronic Chronic Bronchitis Chronic Obstructive Airway Disease CRISPR/Cas technology Cytosol Data defense response Degradation Pathway Desert Climate Development Diet Dietary Supplementation Disease disease registry Dose Dust Epithelial Epithelial Cells epithelial to mesenchymal transition Epithelium Erythroid exposure route Exposure to Fibrosis Functional disorder Gene Expression Gene Targeting Generations Goals Health high risk In Vitro in vivo Infiltration Inflammation Inflammatory Ingestion Inhalation Injury Intervention Iron Lung Lung diseases Lung Inflammation lung injury Maintenance Malignant Neoplasms Measures Mediating Metal exposure Metals Mining mitochondrial dysfunction Molecular Mus mutant Non-Malignant Nuclear Occupational Health Organ Organelles Outcome Oxidative Stress particle Particulate Pathway interactions Poison Population Intervention Populations at Risk Preventive Preventive treatment prophylactic protein aggregate Proteins Public Health Pulmonary Emphysema remediation Reporting Research Respiratory physiology response Risk Role Severities Side Site Soil Structure Sulforaphane superfund site Supplementation Tail Testing Therapeutic Tight Junctions Tissues Toxic effect transcription factor transcriptomics wasting |
| Do extra-articular manifestations influence outcome in ankylosing spondylitis? 12-year results from OASIS 期刊论文
发表期刊: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 出版年: 2016, 卷号: 34, 期号: 2, 页码: 214-221
作者: Essers, I.; Ramiro, S.; Stolwijk, C.; Blaauw, M.; Landewe, R.; van der Heijde, D.; Van den Bosch, F.; Dougados, M.; van Tubergen, A.
收藏 | 浏览/下载：35/0 | 提交时间：2019/11/29
ankylosing spondylitis uveitis psoriasis inflammatory bowel disease outcome measures |
| 不同时期中国非ST段抬高型急性冠状动脉综合征患者临床特征与预后 期刊论文
发表期刊: 中华心血管病杂志. 出版年: 2014, 卷号: 42, 期号: 8, 页码: 655-660
作者: 白莹; 梁岩; 谭慧琼; 乔树宾; 张峻; 杨艳敏; 章晏; 朱俊
收藏 | 浏览/下载：42/0 | 提交时间：2019/11/29
Coronary disease Angioplasty,transluminal,percutaneous coronary Drug therapy Treatment outcome |
