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Lipid Secretion by Parasitic Cells of Coccidioides Contributes to Disseminated Disease 期刊论文
发表期刊: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 出版年: 2021, 卷号: 11
作者:  Pelaez-Jaramillo, Carlos Alberto;  Jimenez-Alzate, Maria Del Pilar;  Araque-Marin, Pedronel;  Hung, Chiung-Yu;  Castro-Lopez, Natalia;  Cole, Garry T.
收藏  |  浏览/下载：29/0  |  提交时间：2021/07/30
Coccidioides  spherule outer wall  phospholipids  sphingolipids  immunomodulation  fungal lipids  SOW-lipid extract  
Apply an imaging flow cytometry method to screen chemical libraries for identifying and repurposing novel drugs against coccidioidomycosis 项目
项目编号: 1R21AI149015-01. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2020-2021
负责人:  HUNG, CHIUNG YU
收藏  |  浏览/下载：24/0  |  提交时间：2021/08/12
acute infection  Adverse effects  Affect  Americas  Amphotericin B  Animals  Antifungal Agents  Antimicrobial Resistance  Area  base  Biological Assay  Caliber  Caspofungin  Cell Membrane Permeability  Cell Wall  Cells  chemotherapy  Clinical  Coccidioides  Coccidioides immitis  Coccidioides posadasii  Coccidioidomycosis  Communities  Containment  Contracts  cost  Cryptococcus  Cryptococcus neoformans  Cytochrome P450  Cytology  cytotoxicity  Data  Databases  desert fever  Development  Diagnosis  Disease  Dose  drug development  Drug usage  drug use screening  Flow Cytometry  Fluconazole  follow-up  fungus  Goals  Government  Growth  Hand  Human  Hyphae  Image  In Vitro  in vivo  Incubated  indexing  Infection  Inhalation  insight  Lead  Legal patent  Libraries  Life Cycle Stages  Lower respiratory tract structure  Lung  Lung diseases  Medical  Medical Research  Meningitis  Methods  Mexico  Microscope  Morphology  Motivation  Mycoses  Neuraxis  novel  novel strategies  novel therapeutics  off-patent  pathogen  pathogenic fungus  Patients  Pharmaceutical Preparations  Pharmacology  Phase IV Clinical Trials  Phenotype  Pneumonia  preclinical development  prevent  Process  Property  Reporting  Reproduction spores  Research Personnel  resistant strain  Resolution  screening  small molecule libraries  Soil  South America  Southwestern United States  Speed  success  Symptoms  synergism  Techniques  Testing  The science of Mycology  Time  Toxic effect  United States  United States National Institutes of Health  Vaccines  
Card9-and MyD88-Mediated Gamma Interferon and Nitric Oxide Production Is Essential for Resistance to Subcutaneous Coccidioides posadasii Infection 期刊论文
发表期刊: INFECTION AND IMMUNITY. 出版年: 2016, 卷号: 84, 期号: 4, 页码: 1166-1175
作者:  Hung, Chiung-Yu;  Castro-Lopez, Natalia;  Cole, Garry T.
收藏  |  浏览/下载：12/0  |  提交时间：2019/11/29
Comparative genomic analyses of the human fungal pathogens Coccidioides and their relatives 期刊论文
发表期刊: GENOME RESEARCH. 出版年: 2009, 卷号: 19, 期号: 10, 页码: 1722-1731
作者:  Sharpton, Thomas J.;  Stajich, Jason E.;  Rounsley, Steven D.;  Gardner, Malcolm J.;  Wortman, Jennifer R.;  Jordar, Vinita S.;  Maiti, Rama;  Kodira, Chinnappa D.;  Neafsey, Daniel E.;  Zeng, Qiandong;  Hung, Chiung-Yu;  McMahan, Cody;  Muszewska, Anna;  Grynberg, Marcin;  Mandel, M. Alejandra;  Kellner, Ellen M.;  Barker, Bridget M.;  Galgiani, John N.;  Orbach, Marc J.;  Kirkland, Theo N.;  Cole, Garry T.;  Henn, Matthew R.;  Birren, Bruce W.;  Taylor, John W.
收藏  |  浏览/下载：20/0  |  提交时间：2019/11/28
Multivalent recombinant protein vaccine against coccidioidomycosis 期刊论文
发表期刊: INFECTION AND IMMUNITY. 出版年: 2006, 卷号: 74, 期号: 10, 页码: 5802-5813
作者:  Tarcha, Eric J.;  Basrur, Venkatesha;  Hung, Chiung-Yu;  Gardner, Malcolm J.;  Cole, Garry T.
收藏  |  浏览/下载：21/0  |  提交时间：2019/11/28