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| Project 1 - Environmental Project 1 - EP1 - Immobilization of U, As, and Co-occurring Metals in Mine Wastes 项目
项目编号: 5P42ES025589-04. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: CERRATO, JOSE MANUEL
  收藏 | 浏览/下载：4/0 | 提交时间：2021/08/12
Address Adsorption Aerobic Affect Amendment aqueous Basic Science bioaccumulation Biological Carbonates Characteristics Chemicals Chemistry Climate Climate Controls Collaborations Communities Complement contaminated drinking water cultural values Custom Decision Making Desert Climate Development Ecology Engineering Environment Environmental Engineering technology Environmental Microbiology experience experimental study Exposure to Exudate Geographic Factor Goals Hazardous Substances Hazardous Waste Sites Health Home environment Human IGFBP2 gene Immobilization In Vitro Individual Ingestion innovation inorganic phosphate interfacial Intervention iron oxide Knowledge Laboratories Ligands mathematical model Measures member metagenome Metal exposure metal poisoning Metals Methods microbiome microbiome alteration microorganism Microscopy migration Minerals Mining Modeling Molecular Native Americans Navajo New Mexico next generation sequencing Outcomes Research Oxides Pattern Phase Pilot Projects Plant Roots Plants Play Population Precipitation prevent Process programs Pueblo Race Rain Reaction remediation Research Resources Risk Risk Reduction Role Sampling Science Scientist Seasons Site Soil Source Spectrum Analysis Superfund Surface System Techniques Testing tool Toxic effect toxic metal tribal community tribal lands Tribes Underserved Population Universities uptake Uranium wasting Water water flow |
| Project 2 - Macrophage regulation of fibrosis and scarring during tissue regeneration 项目
项目编号: 5P20GM104318-08. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: GODWIN, JAMES W
收藏 | 浏览/下载：5/0 | 提交时间：2021/08/12
Address Adult Aging Animal Model Antigens Biological Assay Biological Models Brain Carbohydrates Cell Proliferation cell type Cells cellular targeting Cessation of life Cicatrix Comparative Biology Complex crosslink Development Disease Enzymes Epithelial Epithelial Cells Epithelium Exposure to Extracellular Matrix Fibroblasts Fibrosis Gene Expression Gene Expression Profile Genes Goals healing Healthcare Heart Human human tissue Immune Infection Infiltration Injury Innate Immune System innovation insight Label Laboratories Leukocytes limb amputation limb regeneration Limb structure Liver Lung macrophage Mammals Measures Mediating Mesenchymal Methods Modernization Molecular Myofibroblast Natural regeneration novel Operative Surgical Procedures Organ overexpression Patients Pattern Pharmacology Phenotype Play prevent Process progenitor programs Protein-Lysine 6-Oxidase Proteins PTPRC gene Recovery of Function regenerative regenerative therapy Regulation repaired RNA Interference Role Salamander Signal Pathway Signal Transduction Site Source Spinal Cord Stem cells Surface Testing therapy development Time time use tissue regeneration tissue repair Tissues tool transcriptome sequencing transdifferentiation Traumatic injury wound Wound Healing |
| Project 1 - Disruption of CpG island-mediated gene regulation and chromatin architecture in progeria and aging 项目
项目编号: 5P20GM104318-08. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: BECK, SAMUEL
收藏 | 浏览/下载：5/0 | 提交时间：2021/08/12
Address Age of Onset age related Aging Architecture Atherosclerosis Biological Biology of Aging Biomedical Research Blindness Cardiac Myocytes Cell Differentiation process Cells Chromatin Chromosome Mapping Comparative Biology CpG Islands CRISPR/Cas technology Cytosine Data Set de novo mutation Defect Degenerative Disorder Dinucleoside Phosphates Disease DNA DNA Damage DNA Repair Economics Elements epigenetic regulation Euchromatin Fatty Liver Fluorescent in Situ Hybridization Frequencies Gene Expression Gene Expression Regulation Genes Genetic Genetic Transcription genome editing genome-wide Genomic Instability Goals Guanine Hair Hepatocyte Heterochromatin Impairment induced pluripotent stem cell innovation inorganic phosphate insight Lamin Type A Lamins Life Life Expectancy Link Mediating Meta-Analysis Modeling Molecular Morphology mRNA sequencing Musculoskeletal Mutation Natural regeneration Nuclear Nuclear Lamin Nuclear Lamina Pathology Patients Peripheral Physiological Predisposition prevent Process Progeria promoter Property Proteins Psyche structure Public Health Regulation Resources response restoration Skin Structural Protein Symptoms Testing therapy development tissue repair Tissues Undifferentiated |
| Comparative Functional Genomics (CFG) Core 项目
项目编号: 5P20GM104318-08. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: GRABER, JOEL H
收藏 | 浏览/下载：1/0 | 提交时间：2021/08/12
Aging Animal Model Applications Grants Automation base Biological Biology Biomedical Research Cells Centers of Research Excellence chemotherapy Chemotherapy-induced peripheral neuropathy Clinic Collaborations Collection Communities comparative Comparative Biology Computer Analysis computerized tools Consultations Data Data Analyses Data Collection data management Data Set data sharing Databases design Development Education Educational Materials Ensure Epigenetic Process experience experimental analysis Experimental Designs Faculty Feedback Fees functional genomics Funding Generations Genetic Variation genome analysis genome-wide genomic data Genomics Goals Human Resources improved innovation interoperability Joints Lead Legal patent Mammals Medicine member MicroRNAs Modeling multiple data types Natural regeneration novel Organism Output Paper Patients Phase phosphoproteomics Play Procedures Process programs Proteomics Publications Quality Control regenerative Reproducibility Research Research Project Grants Research Support Resources RNA Role Scientist Services small molecule Software Engineering Standardization Students success System Systems Biology Testing theories tissue regeneration tissue repair tool Training Training Programs transcriptomics Untranslated RNA Update Whole Organism Yeasts |
| Project 3 - Defining the role of ribosome protein composition in regulating the selective translation of pro-longevity genes 项目
项目编号: 5P20GM104318-08. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: ROLLINS, JAROD ALTON
收藏 | 浏览/下载：3/0 | 提交时间：2021/08/12
Address Adult Affect Age age related Aging aging gene Animal Model Animals Biology of Aging Caenorhabditis elegans Caloric Restriction Cardiovascular Diseases Chronic Comparative Biology Cost of Illness CRISPR/Cas technology Data Databases Development differential expression Disease Drosophila genus Exposure to Gene Expression Genes Genetic genetic manipulation Genetic Models Genetic Transcription Genetic Translation Genome engineering Goals Health Health Expenditures healthy aging High-Throughput RNA Sequencing Human innovation insight Invertebrates knock-down Life Longevity longevity gene Malignant Neoplasms Mass Spectrum Analysis Mediating Messenger RNA middle age Molecular Molecular Machines mRNA sequencing Mus Natural regeneration Nerve Degeneration novel overexpression Pathway interactions Pharmacologic Substance Polyribosomes polysome profiling prevent Process Proteins Proteomics Ribosomal Proteins Ribosomes Risk Factors RNA Interference Role stressor Testing therapy development Time tissue repair Transcript transcriptomics Translating Translations Vertebrates Yeasts |
| Comparative Animal Models (CAM) Core 项目
项目编号: 5P20GM104318-08. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: YIN, VIRAVUTH P
收藏 | 浏览/下载：19/0 | 提交时间：2021/08/12
Aging Animal Husbandry Animal Model animal resource Animals base Behavioral Biological Biological Models Biological Process Biological Sciences Biology Caenorhabditis elegans Cell Line Centers of Research Excellence comparative Comparative Biology Comparative Study cost Cryopreservation Development Disease Drosophila genus Embryo Ensure experimental study Faculty Fees Fees and Charges Foundations Funding Gene Transfer Techniques Genetic Services Genotype Goals Grant Heart Human human disease human tissue Infrastructure Injury innovation insight International Invertebrates Kidney Knowledge Laboratories laboratory curriculum Lead Legal patent Limb structure Maintenance Medical Medicine member Methods Microinjections Molecular Mus Natural regeneration Organ Oryziinae Paper Patients Phase Process programs Protocols documentation Publications Quarantine recruit regenerative Regenerative Medicine repaired Research research and development Research Personnel Research Project Grants Research Support Resources Salamander Scientist Services small molecule Speed Spinal Cord Structure success Tissue Harvesting tissue repair Tissues Training Programs Transgenic Organisms Translating Vertebrates Visit Visual Zebrafish |
| Administrative Core 项目
项目编号: 5P20GM104318-08. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: STRANGE, KEVIN
收藏 | 浏览/下载：2/0 | 提交时间：2021/08/12
Advisory Committees Aging Applications Grants Biological Biology Biology of Aging Biomedical Research Budgets career career development Centers of Research Excellence Communication Comparative Biology Development Development Plans Elements expectation Faculty Faculty Recruitment Foundations Future Goals Grant Group Meetings Growth Growth and Development function Individual Intellectual Property Laboratories Laboratory Research Leadership Legal patent Logistics Maine Medicine meetings National Institute of General Medical Sciences Natural regeneration operation organizational structure Paper peer peer coaching Peer Review Phase Process Program Evaluation Program Research Project Grants Program Sustainability programs Publications recruit regenerative Reporting Research Research Infrastructure Research Personnel Research Project Grants Resource Development Resources Review Committee Scientist Services success Teacher Professional Development Time tissue repair |
| Optimization of Betulinic Acid analogs for T-type calcium channel inhibition for non-addictive relief of chronic pain 项目
项目编号: 1R41DA050364-01. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-2020
负责人: KHANNA, RAJESH
收藏 | 浏览/下载：14/0 | 提交时间：2021/08/12
Absence of pain sensation addiction Affect Afferent Neurons American Amitriptyline Analgesics analog Antidepressive Agents Arizona Axon Baclofen base Betulinic Acid Biological Assay biophysical properties Calcium Calcium Channel Blockers Calcium Channel Inhibition cancer pain Cancer Patient cancer survival cancer therapy Cell-Mediated Cytolysis Cells central sensitization chemotherapeutic agent chemotherapy Chemotherapy-induced peripheral neuropathy Chemotherapy-Oncologic Procedure Chronic chronic pain chronic pain relief chronic painful condition Clinical Clinical Trials Complex compliance behavior Complication counterscreen Coupled design dorsal horn Dose-Limiting drug discovery Drug Kinetics Drug Targeting duloxetine Dysesthesias effective therapy Effectiveness Esthesia Feeling Fiber G-Protein-Coupled Receptors Human improved In Vitro in vivo Indigenous inhibitor/antagonist Ion Channel Laboratories Lavandula Lead Malignant Neoplasms Mediating Mediator of activation protein Medical Medicinal Plants meetings Modeling Muscle relaxants Natural Products Neuraxis neuronal excitability Neurons Neuropathy neurotoxic neurotoxicity neurotransmission non-opioid analgesic Norepinephrine novel novel therapeutics Numbness Opiate Addiction Opioid opioid misuse Opioid Receptor opioid sparing opioid use Oral Paclitaxel Pain Pain management pain model pain relief pain signal painful neuropathy Paresthesia Pathogenesis Pathway interactions Peripheral Peripheral Nerves Peripheral Nervous System Peripheral Nervous System Diseases Pharmaceutical Preparations Pharmacology Pharmacotherapy Phase Plants Platinum Compounds preclinical study Prevalence Property Protein Isoforms Proteins Quality of life Rattus Regimen Regulation reuptake Role Safety screening Sensory sensory stimulus Serotonin Shock side effect Site small molecule somatosensory Southwestern United States Specificity Spinal Spinal Cord Spinal Ganglia Structure success Survival Rate synaptic function T-Type Calcium Channels taxane Testing Tissues Translating Treatment Protocols Universities venlafaxine Vinca Alkaloids voltage Work |
| Evaluating an Online Adjunctive Support following Intensive Services (OASIS) Strategy for Youth with Selective Mutism 项目
项目编号: 1F31MH122101-01. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-2021
负责人: HONG, NATALIE
收藏 | 浏览/下载：4/0 | 提交时间：2021/08/12
Acute Anxiety Disorders barrier to care base Behavior Therapy career Caring Child Childhood Clinical Clinical Trials Communities community setting Complex design Development Disease remission evidence base Evidence based treatment experience Failure Family Fellowship follow-up Fostering Geography Goals Grant Health Personnel Healthcare Home environment Impairment improved improved outcome Individual innovation Intensive Care Intervention Investigational Therapies Knowledge Lead Linguistics literacy Logistics Maintenance Mental Health Methodology Modernization novel Outcome personalized intervention Population pre-doctoral Predictive Factor prevent programs Psychological reinforcement Psychopathology Randomized Randomized Controlled Trials Relapse Reporting Research Sampling Schools Science Selection for Treatments Services Severities skill acquisition skills social social situation sociodemographics success symptom treatment Symptoms Technology telehealth Time Training Transcend Treatment outcome treatment planning treatment program treatment responders treatment strategy trend Videoconferencing Voluntary Mutism Work Youth |
| Clinical Markers and Monitoring for Post-9-11 Deployment Lung Diseases 项目
项目编号: 1IK2CX001779-01A1. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-2024
负责人: KREFFT, SILPA DHOMA
收藏 | 浏览/下载：0/0 | 提交时间：2021/08/12 |
| Administrative Core 项目
项目编号: 5P20GM103423-20. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: COFFMAN, JAMES A
收藏 | 浏览/下载：2/0 | 提交时间：2021/08/12
Address Administrator Advisory Committees American Association for the Advancement of Science Benchmarking Bioinformatics Biomedical Research Brain Drains Brain Stem Budgets Businesses career career development Centers of Research Excellence Clinical Collaborations Committee Members Communication Research comparative Consultations Development Economics Effectiveness Employment Ensure Evaluation Faculty First Generation College Students formative assessment Fostering functional genomics Goals Grant Hand Health Sciences Human Resources Individual Infrastructure innovation Institution Internships Leadership Logistics Maine meetings Mentors National Institute of General Medical Sciences New England Occupations outreach outreach program Participant Pilot Projects Principal Investigator Private Sector Privatization Procedures Process Program Development Program Research Project Grants programs Research research and development Research Infrastructure Research Personnel Research Project Grants Research Training Resource Sharing Resources Retirement Shapes student mentoring Students success Teacher Professional Development Training Training Activity Training and Infrastructure Training Programs undergraduate student Work |
| Developmental Research Project Program 项目
项目编号: 5P20GM103423-20. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: COFFMAN, JAMES A
收藏 | 浏览/下载：2/0 | 提交时间：2021/08/12
Advisory Committees American Association for the Advancement of Science Appointment Area Award Bioinformatics Biomedical Research career career development Centers of Research Excellence cohesion comparative Computational Biology Development Development Plans Educational process of instructing Educational workshop Evaluation expectation Faculty functional genomics Funding Funding Opportunities Future Goals Guidelines Infrastructure innovation Institution interdisciplinary collaboration International Investigator-Initiated Research Journals Maine meetings Mentors Mentorship Motivation Peer Review Pilot Projects Postdoctoral Fellow preference Principal Investigator probation Program Research Project Grants programs Progress Reports Publications Publishing Research research and development Research Personnel Research Project Grants Research Support Research Training Resources response stem student mentoring Students Teacher Professional Development undergraduate student United States National Institutes of Health Work |
| Research Training and Resources Core 项目
项目编号: 5P20GM103423-20. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: DISNEY, JANE ELIZABETH
收藏 | 浏览/下载：3/0 | 提交时间：2021/08/12
Animals Award base Biological Biomedical Research career Centers of Research Excellence Collaborations comparative Core Facility DNA sequencing Educational process of instructing Educational workshop Engineering Ensure Equipment experience Faculty faculty research Fellowship functional genomics Gene Expression Profiling Generations Genome Graduate Education graduate student Grant Health Health Sciences Image Infrastructure innovation Institution instrument Internships Joints Laboratories laboratory equipment Leadership Maine Medical Nursery Schools Pathway interactions Postdoctoral Fellow programs recruit Research Research Personnel Research Project Summaries Research Training Resources Running Schools Science science education Series Services skills student participation Students summer research symposium Teacher Professional Development Technical Expertise Technology The Jackson Laboratory Training training opportunity Training Programs undergraduate student Universities Work |
| Bioinformatics Core 项目
项目编号: 5P20GM103423-20. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: GRABER, JOEL H
收藏 | 浏览/下载：3/0 | 提交时间：2021/08/12
Address Award Bioinformatics Biomedical Research Cloud Computing Collaborations comparative Complex Computational Biology computer infrastructure computing resources Consult cyber infrastructure cyber-enabled Data Data Analyses data management Data Storage and Retrieval Delaware Educational workshop Ensure experience Experimental Designs Faculty Faculty Recruitment Foundations functional genomics genome analysis genome-wide genomic data Goals Grant Growth High Performance Computing high throughput technology Human Resources Indiana innovation Institution large datasets Maine member Mentors NCI Scholars Program New Hampshire programs Reproducibility Research Research Personnel Research Support Research Training Resources Rhode Island Science Scientist Services Speed student training Students success Teacher Professional Development Technical Expertise Training Training and Infrastructure Training Support undergraduate student Universities Vermont Work |
