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| Splice modulatory therapy for valley fever 项目
项目编号: 1R21AI154106-01. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2020-2022
负责人: BURKART, MICHAEL D.
  收藏 | 浏览/下载：28/0 | 提交时间：2021/08/12
Acute Myelocytic Leukemia Amphotericin B analog anti-cancer Antifungal Agents Arizona Azoles base Biological Biological Markers Biology California cancer cell Cells Chemicals Clinical Coccidioides immitis Coccidioides posadasii Coccidioidomycosis combat Communities desert fever design Development Diagnosis Disease Drug Interactions Dust Evaluation Event Family flu Fluconazole Funding fungus Future Genes Goals high reward high risk Human Incidence Individual Infection Investigation Laboratories Lead Left Life Messenger RNA Modernization Natural Products new therapeutic target next generation novel Oncogenic Outcome outcome forecast Pathway interactions Patients Pattern Pharmaceutical Chemistry Pharmaceutical Preparations Play Pneumonia Positioning Attribute Precipitation preclinical study Preparation programs Reporting RNA Splicing scaffold Seasons Series Side side effect small molecule Spliceosomes Structure System Systems Biology Techniques Testing Therapeutic therapeutic target tool transcriptome transcriptomics Translating Translations United States Work |
| Project 3 - Defining the role of ribosome protein composition in regulating the selective translation of pro-longevity genes 项目
项目编号: 5P20GM104318-08. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: ROLLINS, JAROD ALTON
收藏 | 浏览/下载：20/0 | 提交时间：2021/08/12
Address Adult Affect Age age related Aging aging gene Animal Model Animals Biology of Aging Caenorhabditis elegans Caloric Restriction Cardiovascular Diseases Chronic Comparative Biology Cost of Illness CRISPR/Cas technology Data Databases Development differential expression Disease Drosophila genus Exposure to Gene Expression Genes Genetic genetic manipulation Genetic Models Genetic Transcription Genetic Translation Genome engineering Goals Health Health Expenditures healthy aging High-Throughput RNA Sequencing Human innovation insight Invertebrates knock-down Life Longevity longevity gene Malignant Neoplasms Mass Spectrum Analysis Mediating Messenger RNA middle age Molecular Molecular Machines mRNA sequencing Mus Natural regeneration Nerve Degeneration novel overexpression Pathway interactions Pharmacologic Substance Polyribosomes polysome profiling prevent Process Proteins Proteomics Ribosomal Proteins Ribosomes Risk Factors RNA Interference Role stressor Testing therapy development Time tissue repair Transcript transcriptomics Translating Translations Vertebrates Yeasts |
| Comparative Animal Models (CAM) Core 项目
项目编号: 5P20GM104318-08. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: YIN, VIRAVUTH P
收藏 | 浏览/下载：46/0 | 提交时间：2021/08/12
Aging Animal Husbandry Animal Model animal resource Animals base Behavioral Biological Biological Models Biological Process Biological Sciences Biology Caenorhabditis elegans Cell Line Centers of Research Excellence comparative Comparative Biology Comparative Study cost Cryopreservation Development Disease Drosophila genus Embryo Ensure experimental study Faculty Fees Fees and Charges Foundations Funding Gene Transfer Techniques Genetic Services Genotype Goals Grant Heart Human human disease human tissue Infrastructure Injury innovation insight International Invertebrates Kidney Knowledge Laboratories laboratory curriculum Lead Legal patent Limb structure Maintenance Medical Medicine member Methods Microinjections Molecular Mus Natural regeneration Organ Oryziinae Paper Patients Phase Process programs Protocols documentation Publications Quarantine recruit regenerative Regenerative Medicine repaired Research research and development Research Personnel Research Project Grants Research Support Resources Salamander Scientist Services small molecule Speed Spinal Cord Structure success Tissue Harvesting tissue repair Tissues Training Programs Transgenic Organisms Translating Vertebrates Visit Visual Zebrafish |
| Optimization of Betulinic Acid analogs for T-type calcium channel inhibition for non-addictive relief of chronic pain 项目
项目编号: 1R41DA050364-01. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-2020
负责人: KHANNA, RAJESH
收藏 | 浏览/下载：37/0 | 提交时间：2021/08/12
Absence of pain sensation addiction Affect Afferent Neurons American Amitriptyline Analgesics analog Antidepressive Agents Arizona Axon Baclofen base Betulinic Acid Biological Assay biophysical properties Calcium Calcium Channel Blockers Calcium Channel Inhibition cancer pain Cancer Patient cancer survival cancer therapy Cell-Mediated Cytolysis Cells central sensitization chemotherapeutic agent chemotherapy Chemotherapy-induced peripheral neuropathy Chemotherapy-Oncologic Procedure Chronic chronic pain chronic pain relief chronic painful condition Clinical Clinical Trials Complex compliance behavior Complication counterscreen Coupled design dorsal horn Dose-Limiting drug discovery Drug Kinetics Drug Targeting duloxetine Dysesthesias effective therapy Effectiveness Esthesia Feeling Fiber G-Protein-Coupled Receptors Human improved In Vitro in vivo Indigenous inhibitor/antagonist Ion Channel Laboratories Lavandula Lead Malignant Neoplasms Mediating Mediator of activation protein Medical Medicinal Plants meetings Modeling Muscle relaxants Natural Products Neuraxis neuronal excitability Neurons Neuropathy neurotoxic neurotoxicity neurotransmission non-opioid analgesic Norepinephrine novel novel therapeutics Numbness Opiate Addiction Opioid opioid misuse Opioid Receptor opioid sparing opioid use Oral Paclitaxel Pain Pain management pain model pain relief pain signal painful neuropathy Paresthesia Pathogenesis Pathway interactions Peripheral Peripheral Nerves Peripheral Nervous System Peripheral Nervous System Diseases Pharmaceutical Preparations Pharmacology Pharmacotherapy Phase Plants Platinum Compounds preclinical study Prevalence Property Protein Isoforms Proteins Quality of life Rattus Regimen Regulation reuptake Role Safety screening Sensory sensory stimulus Serotonin Shock side effect Site small molecule somatosensory Southwestern United States Specificity Spinal Spinal Cord Spinal Ganglia Structure success Survival Rate synaptic function T-Type Calcium Channels taxane Testing Tissues Translating Treatment Protocols Universities venlafaxine Vinca Alkaloids voltage Work |
| Data to Action: A Secondary School-based Citizen Science Project to Address Arsenic Contamination of Well Water 项目
项目编号: 3R25GM129796-02S1. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2018-2023
负责人: DISNEY, JANE ELIZABETH
收藏 | 浏览/下载：22/0 | 提交时间：2021/08/12
Address Arsenic base Biomedical Research career Centers for Disease Control and Prevention (U.S.) citizen science Committee Members Communication Communities Competence Computer software Data Data Analyses data portal data sharing drinking water Educational Curriculum Educational workshop Environmental Health Environmental Monitoring experience Future Teacher Generations Goals ground water hazard Health health data Home environment improved innovation Institutes Institution interest Knowledge Lead Learning Link literacy Maine Mathematics Measurable Medicine meetings Mentors Modeling Monitor Motivation Neighborhood Health Center New Hampshire novel Privatization Process programs Public Health recruit remediation Resources role model Rural School Teachers Schools Science science teacher Science, Technology, Engineering and Mathematics Education Scientific Inquiry Scientist Secondary Schools Services skills STEM career Students support network teacher teacher mentor Teacher Professional Development tool Training Translating water sampling water testing web site well water Work |
| Data to Action: A Secondary School-based Citizen Science Project to Address Arsenic Contamination of Well Water 项目
项目编号: 5R25GM129796-03. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2018-2023
负责人: DISNEY, JANE ELIZABETH
收藏 | 浏览/下载：45/0 | 提交时间：2021/08/12
Address Arsenic base Biomedical Research career Centers for Disease Control and Prevention (U.S.) citizen science Committee Members Communication Communities Competence Computer software Data Data Analyses data literacy data portal data sharing drinking water Educational Curriculum Educational workshop Environmental Health Environmental Monitoring experience Future Teacher Generations Goals ground water hazard Health health data Home environment improved innovation Institutes Institution interest Knowledge Lead Learning Link Maine Mathematics Measurable Medicine meetings Mentors Modeling Monitor Motivation Neighborhood Health Center New Hampshire novel Privatization Process programs Public Health recruit remediation Resources role model Rural School Teachers Schools Science science teacher Science, Technology, Engineering and Mathematics Education Scientific Inquiry Scientist Secondary Schools Services skills STEM career Students support network teacher teacher mentor Teacher Professional Development tool Training Translating water sampling water testing web site well water Work |
| Data to Action: A Secondary School-based Citizen Science Project to Address Arsenic Contamination of Well Water 项目
项目编号: 5R25GM129796-02. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2018-2023
负责人: DISNEY, JANE ELIZABETH
收藏 | 浏览/下载：21/0 | 提交时间：2021/08/12
Address Arsenic base Biomedical Research career Centers for Disease Control and Prevention (U.S.) citizen science Committee Members Communication Communities Competence Computer software Data Data Analyses data portal data sharing drinking water Educational Curriculum Educational workshop Environmental Health Environmental Monitoring experience Future Teacher Generations Goals ground water hazard Health health data Home environment improved innovation Institutes Institution interest Knowledge Lead Learning Link literacy Maine Mathematics Measurable Medicine meetings Mentors Modeling Monitor Motivation Neighborhood Health Center New Hampshire novel Privatization Process programs Public Health recruit remediation Resources role model Rural School Teachers Schools Science science teacher Science, Technology, Engineering and Mathematics Education Scientific Inquiry Scientist Secondary Schools Services skills STEM career Students support network teacher teacher mentor Teacher Professional Development tool Training Translating water sampling water testing web site well water Work |
| 干旱区草型浅水湖泊不同富营养化状态临界体系的研究 项目
项目编号: 50569002. 资助机构: CN-NSFC（国家自然科学基金）. 起止日期: 2006-2008
负责人: 李畅游
收藏 | 浏览/下载：14/0 | 提交时间：2021/01/13
Wuliangsuhai Lake information system eutrophication fuzzy pattern recognition Remote Sensing translating analysis |
