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Sea Anemones Responding to Sex Hormones, Oxybenzone, and Benzyl Butyl Phthalate: Transcriptional Profiling and in Silico Modelling Provide Clues to Decipher Endocrine Disruption in Cnidarians 期刊论文
发表期刊: FRONTIERS IN GENETICS. 出版年: 2022, 卷号: 12
作者:  Morgan, Michael B.;  Ross, James;  Ellwanger, Joseph;  Phrommala, Rebecca Martin;  Youngblood, Hannah;  Qualley, Dominic;  Williams, Jacob
收藏  |  浏览/下载：22/0  |  提交时间：2022/03/17
endocrine disruption chemicals  cnidaria  in silico modelling and docking  biomarkers  sex hormones  xenobiotics  transcriptional profiling  hedgehog signaling  
Enhanced Negative Regulation of the DHH Signaling Pathway as a Potential Mechanism of Ascrotal Testes in Laurasiatherians 期刊论文
发表期刊: EVOLUTIONARY BIOLOGY. 出版年: 2021
作者:  Chai, Simin;  Tian, Ran;  Yang, Ying;  Yang, Guang;  Xu, Shixia;  Ren, Wenhua
收藏  |  浏览/下载：54/0  |  提交时间：2021/07/30
DHH (desert hedgehog) signaling pathway  Cryptorchidism  Testicular descent  Leydig cells  Laurasiatherians  
Short-term perfluorooctane sulfonate exposure impairs Leydig cell regeneration in the adult rat testis via targeting hedgehog signaling 期刊论文
发表期刊: ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY. 出版年: 2021, 卷号: 214
作者:  Mao, Baiping;  Li, Chao;  Wen, Zina;  Li, Huitao;  Wang, Yiyan;  Chen, Lanlan;  Lian, Qingquan;  Ge, Ren-Shan
收藏  |  浏览/下载：52/0  |  提交时间：2021/07/30
Leydig cells  Leydig cell regeneration  Perfluorooctane sulfonate  Stem cells  Steroidogenesis  Hedgehog signaling  
Desert hedgehog-primary cilia cross talk shapes mitral valve tissue by organizing smooth muscle actin 期刊论文
发表期刊: DEVELOPMENTAL BIOLOGY. 出版年: 2020, 卷号: 463, 期号: 1, 页码: 26-38
作者:  Fulmer, Diana;  Toomer, Katelynn A.;  Glover, Janiece;  Guo, Lilong;  Moore, Kelsey;  Moore, Reece;  Stairley, Rebecca;  Gensemer, Cortney;  Abrol, Sameer;  Rumph, Mary Kate;  Emetu, Faith;  Lipschutz, Joshua H.;  McDowell, Colin;  Bian, Justin;  Wang, Christina;  Beck, Tyler;  Wessels, Andy;  Renault, Marie-Ange;  Norris, Russell A.
收藏  |  浏览/下载：16/0  |  提交时间：2021/01/07
Primary cilia  Desert hedgehog signaling  Valve development  Myxomatous degeneration  
The role of the Hedgehog signaling pathway in cancer: A comprehensive review 期刊论文
发表期刊: BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES. 出版年: 2018, 卷号: 18, 期号: 1, 页码: 8-20
作者:  Skoda, Ana Marija;  Simovic, Dora;  Karin, Valentina;  Kardum, Vedran;  Vranic, Semir;  Serman, Ljiljana
收藏  |  浏览/下载：14/0  |  提交时间：2019/11/29
Hedgehog signaling pathway  Hh  tumorigenesis  signal transduction  
A highlight on Sonic hedgehog pathway 期刊论文
发表期刊: CELL COMMUNICATION AND SIGNALING. 出版年: 2018, 卷号: 16
作者:  Carballo, Gabriela Basile;  Honorato, Jessica Ribeiro;  Farias de Lopes, Giselle Pinto;  Leite de Sampaio e Spohr, Tania Cristina
收藏  |  浏览/下载：10/0  |  提交时间：2019/11/29
Sonic hedgehog pathway  Canonical Shh signaling  Non-canonical Shh signaling  Clinical-trials  Brain tumors  
Hedgehog Signaling in Malignant Pleural Mesothelioma 期刊论文
发表期刊: GENES. 出版年: 2015, 卷号: 6, 期号: 3, 页码: 500-511
作者:  Felley-Bosco, Emanuela;  Opitz, Isabelle;  Meerang, Mayura
收藏  |  浏览/下载：15/0  |  提交时间：2019/11/29
Hedgehog signaling  malignant pleural mesothelioma  Gli-1  desert Hedgehog  HHip  TCGA  autocrine signaling  paracrine signaling  
A new role for Hedgehogs in juxtacrine signaling 期刊论文
发表期刊: MECHANISMS OF DEVELOPMENT. 出版年: 2014, 卷号: 131, 页码: 137-149
作者:  Pettigrew, Christopher A.;  Asp, Eva;  Emerson, Charles P., Jr.
收藏  |  浏览/下载：7/0  |  提交时间：2019/11/29
Development  Hedgehog  Signaling  Processing  Secretion  
Small-molecule probes to explore cancer 学位论文
学位授予机构: Harvard University. 出版年: 2014
作者:  Schaefer, Giannina Ines
收藏  |  浏览/下载：15/0  |  提交时间：2019/11/29
Cancer  Cancer dependencies  Hedgehog signaling  Small-molecule probes  
TAK-441, a novel investigational smoothened antagonist, delays castration-resistant progression in prostate cancer by disrupting paracrine hedgehog signaling 期刊论文
发表期刊: INTERNATIONAL JOURNAL OF CANCER. 出版年: 2013, 卷号: 133, 期号: 8, 页码: 1955-1966
作者:  Ibuki, Naokazu;  Ghaffari, Mazyar;  Pandey, Mitali;  Iu, Irene;  Fazli, Ladan;  Kashiwagi, Masahide;  Tojo, Hideaki;  Nakanishi, Osamu;  Gleave, Martin E.;  Cox, Michael E.
收藏  |  浏览/下载：22/0  |  提交时间：2019/11/29
prostate cancer  hedgehog signaling  smoothened  small molecule inhibitor