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Development and validation of a liquid chromatography coupled to tandem mass spectrometry method for the simultaneous quantification of five analgesics and sedatives, and six of their active metabolites in human plasma: Application to a clinical study on the determination of neurological death in the intensive care unit 期刊论文
发表期刊: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 出版年: 2020, 卷号: 190
作者:  Jutras, Martin;  Williamson, David;  Chasse, Michael;  Leclair, Gregoire
收藏  |  浏览/下载:18/0  |  提交时间:2021/01/07
Method validation  Liquid chromatography coupled to tandem mass spectrometry  Human plasma  Sedatives  Analgesics  Neurological death  
Naloxone Deserts in NJ Cities: Sociodemographic Factors Which May Impact Retail Pharmacy Naloxone Availability 期刊论文
发表期刊: JOURNAL OF MEDICAL TOXICOLOGY. 出版年: 2019, 卷号: 15, 期号: 2, 页码: 108-111
作者:  Lozo, Kevin W.;  Nelson, Lewis S.;  Ramdin, Christine;  Calello, Diane P.
收藏  |  浏览/下载:11/0  |  提交时间:2021/11/30
Analgesics  Opioid  Naloxone  Pharmaceutical services  
Optimization of Betulinic Acid analogs for T-type calcium channel inhibition for non-addictive relief of chronic pain 项目
项目编号: 1R41DA050364-01. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2019-2020
负责人:  KHANNA, RAJESH
收藏  |  浏览/下载:37/0  |  提交时间:2021/08/12
Absence of pain sensation  addiction  Affect  Afferent Neurons  American  Amitriptyline  Analgesics  analog  Antidepressive Agents  Arizona  Axon  Baclofen  base  Betulinic Acid  Biological Assay  biophysical properties  Calcium  Calcium Channel Blockers  Calcium Channel Inhibition  cancer pain  Cancer Patient  cancer survival  cancer therapy  Cell-Mediated Cytolysis  Cells  central sensitization  chemotherapeutic agent  chemotherapy  Chemotherapy-induced peripheral neuropathy  Chemotherapy-Oncologic Procedure  Chronic  chronic pain  chronic pain relief  chronic painful condition  Clinical  Clinical Trials  Complex  compliance behavior  Complication  counterscreen  Coupled  design  dorsal horn  Dose-Limiting  drug discovery  Drug Kinetics  Drug Targeting  duloxetine  Dysesthesias  effective therapy  Effectiveness  Esthesia  Feeling  Fiber  G-Protein-Coupled Receptors  Human  improved  In Vitro  in vivo  Indigenous  inhibitor/antagonist  Ion Channel  Laboratories  Lavandula  Lead  Malignant Neoplasms  Mediating  Mediator of activation protein  Medical  Medicinal Plants  meetings  Modeling  Muscle relaxants  Natural Products  Neuraxis  neuronal excitability  Neurons  Neuropathy  neurotoxic  neurotoxicity  neurotransmission  non-opioid analgesic  Norepinephrine  novel  novel therapeutics  Numbness  Opiate Addiction  Opioid  opioid misuse  Opioid Receptor  opioid sparing  opioid use  Oral  Paclitaxel  Pain  Pain management  pain model  pain relief  pain signal  painful neuropathy  Paresthesia  Pathogenesis  Pathway interactions  Peripheral  Peripheral Nerves  Peripheral Nervous System  Peripheral Nervous System Diseases  Pharmaceutical Preparations  Pharmacology  Pharmacotherapy  Phase  Plants  Platinum Compounds  preclinical study  Prevalence  Property  Protein Isoforms  Proteins  Quality of life  Rattus  Regimen  Regulation  reuptake  Role  Safety  screening  Sensory  sensory stimulus  Serotonin  Shock  side effect  Site  small molecule  somatosensory  Southwestern United States  Specificity  Spinal  Spinal Cord  Spinal Ganglia  Structure  success  Survival Rate  synaptic function  T-Type Calcium Channels  taxane  Testing  Tissues  Translating  Treatment Protocols  Universities  venlafaxine  Vinca Alkaloids  voltage  Work  
Solid phase extraction coupled to liquid chromatography-tandem mass spectrometry analysis of sulfonamides, tetracyclines, analgesics and hormones in surface water and wastewater in Luxembourg 期刊论文
发表期刊: SCIENCE OF THE TOTAL ENVIRONMENT. 出版年: 2009, 卷号: 407, 期号: 16, 页码: 4736-4743
作者:  Pailler, J. -Y.;  Krein, A.;  Pfister, L.;  Hoffmann, L.;  Guignard, C.
收藏  |  浏览/下载:12/0  |  提交时间:2019/11/28
Surface water  Antibiotics  Estrogens  Analgesics  SPE, HPLC/MS-MS  
Determination of non-steroidal anti-inflammatory drugs in surface water and wastewater by liquid chromatography-tandem mass spectrometry 期刊论文
发表期刊: CHROMATOGRAPHIA. 出版年: 2003, 卷号: 58, 期号: 5-6, 页码: 263-269
作者:  Marchese, S;  Perret, D;  Gentili, A;  Curini, R;  Pastori, F
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/28
column liquid chromatography  mass spectrometry detection  analgesics  salicylic acid  surface water analysis  
RENAL PAPILLARY NECROSIS IN KUWAIT 期刊论文
发表期刊: TROPICAL AND GEOGRAPHICAL MEDICINE. 出版年: 1992, 卷号: 44, 期号: 4, 页码: 331-337
作者:  DAHNIYA, MH;  SZMIGIELSKI, W;  REDDY, CK;  HANNA, RM;  CHERIAN, MJ;  MATTAR, MS;  ALMARZOUK, NF
收藏  |  浏览/下载:8/0  |  提交时间:2019/11/28
RENAL PAPILLARY NECROSIS  DEHYDRATION  ANALGESICS  KUWAIT