干旱区生态环境知识资源中心(Arid): Determination of non-steroidal anti-inflammatory drugs in surface water and wastewater by liquid chromatography-tandem mass spectrometry

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DOI	10.1365/s10337-003-0052-4
	Determination of non-steroidal anti-inflammatory drugs in surface water and wastewater by liquid chromatography-tandem mass spectrometry
	Marchese, S; Perret, D; Gentili, A; Curini, R; Pastori, F
通讯作者	Marchese, S
来源期刊	CHROMATOGRAPHIA
ISSN	0009-5893
出版年	2003
卷号	58 期号:5-6 页码:263-269
英文摘要	An analytical method based on liquid chromatography-tandem mass spectrometry (LC-MS-MS) has been developed for the determination of pharmaceutical compounds in water samples. The drugs investigated were the analgesics: Ibuprofen, Fenoprofen, Ketoprofen, Naproxen, and Diclofenac and the decomposition product of acetylsalicylic acid: salicylic acid. The selected compounds are acidic, very polar and all are analgesic compounds that can be purchased without medical prescription. Sample enrichment of water samples was achieved by solid-phase extraction procedure (SPE), using Waters Oasis HLB cartridges followed by LC-MS-MS. A narrow-bore 2.1 min i.d., reversed phase LC C-18 column was used to chromatograph analytes. Average recoveries from 1 L samples varied 75-95% and the detection limits are <1 ng L-1. The method developed was applied to real samples from wastewater and surface waters of Lazio country (Italy).
英文关键词	column liquid chromatography mass spectrometry detection analgesics salicylic acid surface water analysis
类型	Article
语种	英语
国家	Italy
收录类别	SCI-E
WOS记录号	WOS:000185393700004
WOS关键词	AQUATIC ENVIRONMENT ; ACIDIC HERBICIDES ; DRINKING-WATER ; CLOFIBRIC ACID ; PHARMACEUTICALS ; SEWAGE ; ANTIBIOTICS ; PESTICIDES ; PRODUCTS
WOS类目	Biochemical Research Methods ; Chemistry, Analytical
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/144341
作者单位	(1)Univ Roma La Sapienza, Dipartimento Chim, Lab Chim Sicurezza, I-00185 Rome, Italy
推荐引用方式 GB/T 7714	Marchese, S,Perret, D,Gentili, A,et al. Determination of non-steroidal anti-inflammatory drugs in surface water and wastewater by liquid chromatography-tandem mass spectrometry[J],2003,58(5-6):263-269.
APA	Marchese, S,Perret, D,Gentili, A,Curini, R,&Pastori, F.(2003).Determination of non-steroidal anti-inflammatory drugs in surface water and wastewater by liquid chromatography-tandem mass spectrometry.CHROMATOGRAPHIA,58(5-6),263-269.
MLA	Marchese, S,et al."Determination of non-steroidal anti-inflammatory drugs in surface water and wastewater by liquid chromatography-tandem mass spectrometry".CHROMATOGRAPHIA 58.5-6(2003):263-269.