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| Project 1 - Environmental Project 1 - EP1 - Immobilization of U, As, and Co-occurring Metals in Mine Wastes 项目 项目编号: 5P42ES025589-04. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2019- 负责人: CERRATO, JOSE MANUEL 收藏  |  浏览/下载:4/0  |  提交时间:2021/08/12 Address Adsorption Aerobic Affect Amendment aqueous Basic Science bioaccumulation Biological Carbonates Characteristics Chemicals Chemistry Climate Climate Controls Collaborations Communities Complement contaminated drinking water cultural values Custom Decision Making Desert Climate Development Ecology Engineering Environment Environmental Engineering technology Environmental Microbiology experience experimental study Exposure to Exudate Geographic Factor Goals Hazardous Substances Hazardous Waste Sites Health Home environment Human IGFBP2 gene Immobilization In Vitro Individual Ingestion innovation inorganic phosphate interfacial Intervention iron oxide Knowledge Laboratories Ligands mathematical model Measures member metagenome Metal exposure metal poisoning Metals Methods microbiome microbiome alteration microorganism Microscopy migration Minerals Mining Modeling Molecular Native Americans Navajo New Mexico next generation sequencing Outcomes Research Oxides Pattern Phase Pilot Projects Plant Roots Plants Play Population Precipitation prevent Process programs Pueblo Race Rain Reaction remediation Research Resources Risk Risk Reduction Role Sampling Science Scientist Seasons Site Soil Source Spectrum Analysis Superfund Surface System Techniques Testing tool Toxic effect toxic metal tribal community tribal lands Tribes Underserved Population Universities uptake Uranium wasting Water water flow |
| Project 2 - Macrophage regulation of fibrosis and scarring during tissue regeneration 项目 项目编号: 5P20GM104318-08. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2019- 负责人: GODWIN, JAMES W 收藏  |  浏览/下载:5/0  |  提交时间:2021/08/12 Address Adult Aging Animal Model Antigens Biological Assay Biological Models Brain Carbohydrates Cell Proliferation cell type Cells cellular targeting Cessation of life Cicatrix Comparative Biology Complex crosslink Development Disease Enzymes Epithelial Epithelial Cells Epithelium Exposure to Extracellular Matrix Fibroblasts Fibrosis Gene Expression Gene Expression Profile Genes Goals healing Healthcare Heart Human human tissue Immune Infection Infiltration Injury Innate Immune System innovation insight Label Laboratories Leukocytes limb amputation limb regeneration Limb structure Liver Lung macrophage Mammals Measures Mediating Mesenchymal Methods Modernization Molecular Myofibroblast Natural regeneration novel Operative Surgical Procedures Organ overexpression Patients Pattern Pharmacology Phenotype Play prevent Process progenitor programs Protein-Lysine 6-Oxidase Proteins PTPRC gene Recovery of Function regenerative regenerative therapy Regulation repaired RNA Interference Role Salamander Signal Pathway Signal Transduction Site Source Spinal Cord Stem cells Surface Testing therapy development Time time use tissue regeneration tissue repair Tissues tool transcriptome sequencing transdifferentiation Traumatic injury wound Wound Healing |
| Comparative Functional Genomics (CFG) Core 项目 项目编号: 5P20GM104318-08. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2019- 负责人: GRABER, JOEL H 收藏  |  浏览/下载:1/0  |  提交时间:2021/08/12 Aging Animal Model Applications Grants Automation base Biological Biology Biomedical Research Cells Centers of Research Excellence chemotherapy Chemotherapy-induced peripheral neuropathy Clinic Collaborations Collection Communities comparative Comparative Biology Computer Analysis computerized tools Consultations Data Data Analyses Data Collection data management Data Set data sharing Databases design Development Education Educational Materials Ensure Epigenetic Process experience experimental analysis Experimental Designs Faculty Feedback Fees functional genomics Funding Generations Genetic Variation genome analysis genome-wide genomic data Genomics Goals Human Resources improved innovation interoperability Joints Lead Legal patent Mammals Medicine member MicroRNAs Modeling multiple data types Natural regeneration novel Organism Output Paper Patients Phase phosphoproteomics Play Procedures Process programs Proteomics Publications Quality Control regenerative Reproducibility Research Research Project Grants Research Support Resources RNA Role Scientist Services small molecule Software Engineering Standardization Students success System Systems Biology Testing theories tissue regeneration tissue repair tool Training Training Programs transcriptomics Untranslated RNA Update Whole Organism Yeasts |
| Project 3 - Defining the role of ribosome protein composition in regulating the selective translation of pro-longevity genes 项目 项目编号: 5P20GM104318-08. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2019- 负责人: ROLLINS, JAROD ALTON 收藏  |  浏览/下载:3/0  |  提交时间:2021/08/12 Address Adult Affect Age age related Aging aging gene Animal Model Animals Biology of Aging Caenorhabditis elegans Caloric Restriction Cardiovascular Diseases Chronic Comparative Biology Cost of Illness CRISPR/Cas technology Data Databases Development differential expression Disease Drosophila genus Exposure to Gene Expression Genes Genetic genetic manipulation Genetic Models Genetic Transcription Genetic Translation Genome engineering Goals Health Health Expenditures healthy aging High-Throughput RNA Sequencing Human innovation insight Invertebrates knock-down Life Longevity longevity gene Malignant Neoplasms Mass Spectrum Analysis Mediating Messenger RNA middle age Molecular Molecular Machines mRNA sequencing Mus Natural regeneration Nerve Degeneration novel overexpression Pathway interactions Pharmacologic Substance Polyribosomes polysome profiling prevent Process Proteins Proteomics Ribosomal Proteins Ribosomes Risk Factors RNA Interference Role stressor Testing therapy development Time tissue repair Transcript transcriptomics Translating Translations Vertebrates Yeasts |
| Optimization of Betulinic Acid analogs for T-type calcium channel inhibition for non-addictive relief of chronic pain 项目 项目编号: 1R41DA050364-01. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2019-2020 负责人: KHANNA, RAJESH 收藏  |  浏览/下载:14/0  |  提交时间:2021/08/12 Absence of pain sensation addiction Affect Afferent Neurons American Amitriptyline Analgesics analog Antidepressive Agents Arizona Axon Baclofen base Betulinic Acid Biological Assay biophysical properties Calcium Calcium Channel Blockers Calcium Channel Inhibition cancer pain Cancer Patient cancer survival cancer therapy Cell-Mediated Cytolysis Cells central sensitization chemotherapeutic agent chemotherapy Chemotherapy-induced peripheral neuropathy Chemotherapy-Oncologic Procedure Chronic chronic pain chronic pain relief chronic painful condition Clinical Clinical Trials Complex compliance behavior Complication counterscreen Coupled design dorsal horn Dose-Limiting drug discovery Drug Kinetics Drug Targeting duloxetine Dysesthesias effective therapy Effectiveness Esthesia Feeling Fiber G-Protein-Coupled Receptors Human improved In Vitro in vivo Indigenous inhibitor/antagonist Ion Channel Laboratories Lavandula Lead Malignant Neoplasms Mediating Mediator of activation protein Medical Medicinal Plants meetings Modeling Muscle relaxants Natural Products Neuraxis neuronal excitability Neurons Neuropathy neurotoxic neurotoxicity neurotransmission non-opioid analgesic Norepinephrine novel novel therapeutics Numbness Opiate Addiction Opioid opioid misuse Opioid Receptor opioid sparing opioid use Oral Paclitaxel Pain Pain management pain model pain relief pain signal painful neuropathy Paresthesia Pathogenesis Pathway interactions Peripheral Peripheral Nerves Peripheral Nervous System Peripheral Nervous System Diseases Pharmaceutical Preparations Pharmacology Pharmacotherapy Phase Plants Platinum Compounds preclinical study Prevalence Property Protein Isoforms Proteins Quality of life Rattus Regimen Regulation reuptake Role Safety screening Sensory sensory stimulus Serotonin Shock side effect Site small molecule somatosensory Southwestern United States Specificity Spinal Spinal Cord Spinal Ganglia Structure success Survival Rate synaptic function T-Type Calcium Channels taxane Testing Tissues Translating Treatment Protocols Universities venlafaxine Vinca Alkaloids voltage Work |
| Project 1 - Environmental Project 1 - EP1 - Immobilization of U, As, and Co-occurring Metals in Mine Wastes 项目 项目编号: 5P42ES025589-02. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2018- 负责人: CERRATO, JOSE MANUEL 收藏  |  浏览/下载:3/0  |  提交时间:2021/08/12 Address Adsorption Aerobic Affect Amendment aqueous Basic Science bioaccumulation Biological Carbonates Characteristics Chemicals Chemistry Climate Climate Controls Collaborations Communities Complement contaminated drinking water cultural values Custom Decision Making Desert Climate Development Ecology Engineering Environment Environmental Engineering technology Environmental Microbiology experience experimental study Exposure to Exudate Geographic Factor Goals Hazardous Substances Hazardous Waste Sites Health Home environment Human IGFBP2 gene Immobilization In Vitro Individual Ingestion innovation inorganic phosphate interfacial Intervention Knowledge Laboratories Ligands mathematical model Measures member metagenome Metal exposure metal poisoning Metals Methods microbiome microbiome alteration microorganism Microscopy migration Minerals Mining Modeling Molecular Native Americans Navajo New Mexico next generation sequencing Outcomes Research Oxides Pattern Phase Pilot Projects Plant Roots Plants Play Population Precipitation prevent Process programs Pueblo Race Rain Reaction remediation Research Resources Risk Risk Reduction Role Sampling Science Scientist Seasons Site Soil Source Spectrum Analysis Superfund Surface System Techniques Testing tool Toxic effect toxic metal tribal community tribal lands Tribes Underserved Population Universities uptake Uranium wasting Water water flow |
| Data to Action: A Secondary School-based Citizen Science Project to Address Arsenic Contamination of Well Water 项目 项目编号: 3R25GM129796-02S1. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2018-2023 负责人: DISNEY, JANE ELIZABETH 收藏  |  浏览/下载:10/0  |  提交时间:2021/08/12 Address Arsenic base Biomedical Research career Centers for Disease Control and Prevention (U.S.) citizen science Committee Members Communication Communities Competence Computer software Data Data Analyses data portal data sharing drinking water Educational Curriculum Educational workshop Environmental Health Environmental Monitoring experience Future Teacher Generations Goals ground water hazard Health health data Home environment improved innovation Institutes Institution interest Knowledge Lead Learning Link literacy Maine Mathematics Measurable Medicine meetings Mentors Modeling Monitor Motivation Neighborhood Health Center New Hampshire novel Privatization Process programs Public Health recruit remediation Resources role model Rural School Teachers Schools Science science teacher Science, Technology, Engineering and Mathematics Education Scientific Inquiry Scientist Secondary Schools Services skills STEM career Students support network teacher teacher mentor Teacher Professional Development tool Training Translating water sampling water testing web site well water Work |
| Data to Action: A Secondary School-based Citizen Science Project to Address Arsenic Contamination of Well Water 项目 项目编号: 5R25GM129796-03. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2018-2023 负责人: DISNEY, JANE ELIZABETH 收藏  |  浏览/下载:27/0  |  提交时间:2021/08/12 Address Arsenic base Biomedical Research career Centers for Disease Control and Prevention (U.S.) citizen science Committee Members Communication Communities Competence Computer software Data Data Analyses data literacy data portal data sharing drinking water Educational Curriculum Educational workshop Environmental Health Environmental Monitoring experience Future Teacher Generations Goals ground water hazard Health health data Home environment improved innovation Institutes Institution interest Knowledge Lead Learning Link Maine Mathematics Measurable Medicine meetings Mentors Modeling Monitor Motivation Neighborhood Health Center New Hampshire novel Privatization Process programs Public Health recruit remediation Resources role model Rural School Teachers Schools Science science teacher Science, Technology, Engineering and Mathematics Education Scientific Inquiry Scientist Secondary Schools Services skills STEM career Students support network teacher teacher mentor Teacher Professional Development tool Training Translating water sampling water testing web site well water Work |
| Data to Action: A Secondary School-based Citizen Science Project to Address Arsenic Contamination of Well Water 项目 项目编号: 5R25GM129796-02. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2018-2023 负责人: DISNEY, JANE ELIZABETH 收藏  |  浏览/下载:5/0  |  提交时间:2021/08/12 Address Arsenic base Biomedical Research career Centers for Disease Control and Prevention (U.S.) citizen science Committee Members Communication Communities Competence Computer software Data Data Analyses data portal data sharing drinking water Educational Curriculum Educational workshop Environmental Health Environmental Monitoring experience Future Teacher Generations Goals ground water hazard Health health data Home environment improved innovation Institutes Institution interest Knowledge Lead Learning Link literacy Maine Mathematics Measurable Medicine meetings Mentors Modeling Monitor Motivation Neighborhood Health Center New Hampshire novel Privatization Process programs Public Health recruit remediation Resources role model Rural School Teachers Schools Science science teacher Science, Technology, Engineering and Mathematics Education Scientific Inquiry Scientist Secondary Schools Services skills STEM career Students support network teacher teacher mentor Teacher Professional Development tool Training Translating water sampling water testing web site well water Work |