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Graph-pMHC: graph neural network approach to MHC class II peptide presentation and antibody immunogenicity 期刊论文
发表期刊: BRIEFINGS IN BIOINFORMATICS. 出版年: 2024, 卷号: 25, 期号: 3
作者:  Thrift, William John;  Perera, Jason;  Cohen, Sivan;  Lounsbury, Nicolas W.;  Gurung, Hem R.;  Rose, Christopher M.;  Chen, Jieming;  Jhunjhunwala, Suchit;  Liu, Kai
收藏  |  浏览/下载：24/0  |  提交时间：2024/10/04
graph neural networks  pMHC-II  anti-drug antibody  immunogenicity prediction  deep learning  
BioPhi: A platform for antibody design, humanization, and humanness evaluation based on natural antibody repertoires and deep learning 期刊论文
发表期刊: MABS. 出版年: 2022, 卷号: 14, 期号: 1
作者:  Prihoda, David;  Maamary, Jad;  Waight, Andrew;  Juan, Veronica;  Fayadat-Dilman, Laurence;  Svozil, Daniel;  Bitton, Danny A.
收藏  |  浏览/下载：28/0  |  提交时间：2022/03/17
Antibody humanization  humanness  human-likeness  immunogenicity  deimmunization  immune repertoires  machine learning  deep learning  
Immune deserts in head and neck squamous cell carcinoma: A review of challenges and opportunities for modulating the tumor immune microenvironment 期刊论文
发表期刊: ORAL ONCOLOGY. 出版年: 2021, 卷号: 120
作者:  Farlow, Janice L.;  Brenner, J. Chad;  Lei, Yu L.;  Chinn, Steven B.
收藏  |  浏览/下载：30/0  |  提交时间：2021/11/19
Head and neck cancer  Squamous cell carcinoma  Cancer immunology  Tumor microenvironment  Antigenicity  Immunogenicity  Immunotherapy  Immune desert  Immune evasion  Immunosuppression