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Individualized Assessment of Brain Aβ Deposition With fMRI Using Deep Learning 期刊论文
发表期刊: IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS. 出版年: 2023, 卷号: 27, 期号: 11, 页码: 5430-5438
作者:  Li, Chaolin;  Liu, Mianxin;  Xia, Jing;  Mei, Lang;  Yang, Qing;  Shi, Feng;  Zhang, Han;  Shen, Dinggang
收藏  |  浏览/下载:27/0  |  提交时间:2024/09/29
Functional connectivity  high-order functional connectivity  amyloid beta  graph convolutional networks  
Disrupted Excitation-Inhibition Balance in Cognitively Normal Individuals at Risk of Alzheimer's Disease 期刊论文
发表期刊: JOURNAL OF ALZHEIMERS DISEASE. 出版年: 2023, 卷号: 95, 期号: 4, 页码: 1449-1467
作者:  Fortel, Igor;  Zhan, Liang;  Ajilore, Olusola;  Wu, Yichao;  Mackin, Scott;  Leow, Alex
收藏  |  浏览/下载:21/0  |  提交时间:2024/09/29
Alzheimer's disease  amyloid-beta  apolipoprotein E  brain dynamics  hyperexcitation  excitation-inhibition balance  
Identifying Mild Alzheimer's Disease With First 30-Min 11C-PiB PET Scan 期刊论文
发表期刊: FRONTIERS IN AGING NEUROSCIENCE. 出版年: 2022, 卷号: 14
作者:  Shen, Chushu;  Wang, Zhenguo;  Chen, Hongzhao;  Bai, Yan;  Li, Xiaochen;  Liang, Dong;  Liu, Xin;  Zheng, Hairong;  Wang, Meiyun;  Yang, Yongfeng;  Wang, Haifeng;  Sun, Tao
收藏  |  浏览/下载:30/0  |  提交时间:2024/09/20
Alzheimer's disease  C-11-PiB PET  beta-amyloid  imaging protocol  dynamic imaging  
Predicting Brain Amyloid-β PET Grades with Graph Convolutional Networks Based on Functional MRI and Multi-Level Functional Connectivity 期刊论文
发表期刊: JOURNAL OF ALZHEIMERS DISEASE. 出版年: 2022, 卷号: 86, 期号: 4, 页码: 1679-1693
作者:  Li, Chaolin;  Liu, Mianxin;  Xia, Jing;  Mei, Lang;  Yang, Qing;  Shi, Feng;  Zhang, Han;  Shen, Dinggang
收藏  |  浏览/下载:23/0  |  提交时间:2024/09/20
Amyloid-beta  brain network  functional connectivity  graph convolutional neural network  positron emission tomography  
Identification of key stabilizing interactions of amyloid-beta oligomers based on fragment molecular orbital calculations on macrocyclic beta-hairpin peptides 期刊论文
发表期刊: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS. 出版年: 2021
作者:  Firouzi, Rohoullah;  Noohi, Bahare
收藏  |  浏览/下载:43/0  |  提交时间:2021/11/29
amyloid oligomers  amyloid-beta  fragment molecular orbital  macrocyclic peptides  protein-protein interaction  stabilizing interactions  
Regional amyloid accumulation predicts memory decline in initially cognitively unimpaired individuals 期刊论文
发表期刊: ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING. 出版年: 2021, 卷号: 13, 期号: 1
作者:  Collij, Lyduine E.;  Mastenbroek, Sophie E.;  Salvado, Gemma;  Wink, Alle Meije;  Visser, Pieter Jelle;  Barkhof, Frederik;  Berckel, Bart N. M.;  Alves, Isadora Lopes
收藏  |  浏览/下载:38/0  |  提交时间:2021/11/19
Alzheimer's disease  amyloid beta  longitudinal  positron emission tomography  regional  
Predicting Brain Amyloid Using Multivariate Morphometry Statistics, Sparse Coding, and Correntropy: Validation in 1,101 Individuals From the ADNI and OASIS Databases 期刊论文
发表期刊: FRONTIERS IN NEUROSCIENCE. 出版年: 2021, 卷号: 15
作者:  Wu, Jianfeng;  Dong, Qunxi;  Gui, Jie;  Zhang, Jie;  Su, Yi;  Chen, Kewei;  Thompson, Paul M.;  Caselli, Richard J.;  Reiman, Eric M.;  Ye, Jieping;  Wang, Yalin
收藏  |  浏览/下载:30/0  |  提交时间:2021/11/19
Alzheimer's disease  hippocampal multivariate morphometry statistics  Dictionary and Correntropy-induced Sparse Coding  beta-amyloid burden  ADNI and OASIS database  
Phytochemicals from Achillea fragrantissima are Modulators of A beta PP Metabolism 期刊论文
发表期刊: JOURNAL OF ALZHEIMERS DISEASE. 出版年: 2018, 卷号: 66, 期号: 4, 页码: 1425-1435
作者:  Bartolotti, Nancy;  Disouky, Ahmed;  Kalinski, Arthur;  Elmann, Anat;  Lazarov, Orly
收藏  |  浏览/下载:21/0  |  提交时间:2019/11/29
Achillolide A  Alzheimer’s disease  amyloid-beta protein precursor  flavonoids  sesquiterpene lactones  3, 5, 4 ’-trihydroxy-6, 7, 3 ’-trimethoxyflavone  
N-Acetylcysteine Prevents the Spatial Memory Deficits and the Redox-Dependent RyR2 Decrease Displayed by an Alzheimer’s Disease Rat Model 期刊论文
发表期刊: FRONTIERS IN AGING NEUROSCIENCE. 出版年: 2018, 卷号: 10
作者:  More, Jamileth;  Galusso, Nadia;  Veloso, Pablo;  Montecinos, Luis;  Pablo Finkelstein, Jose;  Sanchez, Gina;  Bull, Ricardo;  Luis Valdes, Jose;  Hidalgo, Cecilia;  Paula-Lima, Andrea
收藏  |  浏览/下载:17/0  |  提交时间:2019/11/29
amyloid beta peptide 1-42  calcium signaling  reactive oxygen species  spatial memory training  antioxidants  early genes  glutathione  
Region-specific Distribution of β-Amyloid and Cytokine Expression in TgCRND8 Mice 学位论文
出版年: 2010
作者:  Ma;Keran
收藏  |  浏览/下载:13/0  |  提交时间:2019/11/29
Alzheimer's Disease  Beta-Amyloid  Neuroinflammation  0317  0571  0982