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Apply an imaging flow cytometry method to screen chemical libraries for identifying and repurposing novel drugs against coccidioidomycosis 项目
项目编号: 1R21AI149015-01. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2020-2021
负责人:  HUNG, CHIUNG YU
收藏  |  浏览/下载:27/0  |  提交时间:2021/08/12
acute infection  Adverse effects  Affect  Americas  Amphotericin B  Animals  Antifungal Agents  Antimicrobial Resistance  Area  base  Biological Assay  Caliber  Caspofungin  Cell Membrane Permeability  Cell Wall  Cells  chemotherapy  Clinical  Coccidioides  Coccidioides immitis  Coccidioides posadasii  Coccidioidomycosis  Communities  Containment  Contracts  cost  Cryptococcus  Cryptococcus neoformans  Cytochrome P450  Cytology  cytotoxicity  Data  Databases  desert fever  Development  Diagnosis  Disease  Dose  drug development  Drug usage  drug use screening  Flow Cytometry  Fluconazole  follow-up  fungus  Goals  Government  Growth  Hand  Human  Hyphae  Image  In Vitro  in vivo  Incubated  indexing  Infection  Inhalation  insight  Lead  Legal patent  Libraries  Life Cycle Stages  Lower respiratory tract structure  Lung  Lung diseases  Medical  Medical Research  Meningitis  Methods  Mexico  Microscope  Morphology  Motivation  Mycoses  Neuraxis  novel  novel strategies  novel therapeutics  off-patent  pathogen  pathogenic fungus  Patients  Pharmaceutical Preparations  Pharmacology  Phase IV Clinical Trials  Phenotype  Pneumonia  preclinical development  prevent  Process  Property  Reporting  Reproduction spores  Research Personnel  resistant strain  Resolution  screening  small molecule libraries  Soil  South America  Southwestern United States  Speed  success  Symptoms  synergism  Techniques  Testing  The science of Mycology  Time  Toxic effect  United States  United States National Institutes of Health  Vaccines  
Effect of hanging-type sand fence on characteristics of wind-sand flow fields 期刊论文
发表期刊: WIND AND STRUCTURES. 出版年: 2016, 卷号: 22, 期号: 5, 页码: 555-571
作者:  Cheng, Jian-jun;  Lei, Jia-qiang;  Li, Sheng-yu;  Wang, Hai-feng
收藏  |  浏览/下载:22/0  |  提交时间:2019/11/29
wind-sand environment  wind-sand disaster  hanging-type sand-retaining wall  wind-sand flow fields  wind-blown sand prevention and control  
独头巷道附壁射流通风流场数值模拟研究 期刊论文
发表期刊: 煤炭学报. 出版年: 2004, 卷号: 29, 期号: 4, 页码: 425-428
作者:  王海桥;  施式亮;  刘荣华;  刘何清
收藏  |  浏览/下载:19/0  |  提交时间:2019/11/29
heading face  wall-attached jet  k-epsilon model  flow field  numerical simulation  
Changes in the turbulent boundary layer structure associated with net drag reduction by outer layer manipulators 科技报告
报告编号: NASA-CR-178152, NAS 1.26:178152. 出版年: 1987
作者:  Rashidnia, N.;  Falco, R. E.
收藏  |  浏览/下载:11/0  |  提交时间:2019/11/30
DRAG REDUCTION  MANIPULATORS  PARALLEL PLATES  TURBULENT BOUNDARY LAYER  WIND TUNNEL TESTS  FLOW VISUALIZATION  HOT-WIRE ANEMOMETERS  REYNOLDS STRESS  SPACE-TIME FUNCTIONS  VELOCITY DISTRIBUTION  VORTICES  WALL FLOW  
The aerodynamics of circulation control 科技报告
报告编号: NASA-CR-168662, NAS 1.26:168662, SU-JIAA-TR-41. 出版年: 1981
作者:  Wood, N. J.
收藏  |  浏览/下载:16/0  |  提交时间:2019/11/30
AERODYNAMIC CHARACTERISTICS  CIRCULATION CONTROL AIRFOILS  FLOW DISTRIBUTION  WIND TUNNEL TESTS  COANDA EFFECT  LIFT DEVICES  SLOTS  SUBSONIC WIND TUNNELS  TRAILING EDGES  WALL JETS  
Wind Tunnel Wall Effects at Extreme Force Coefficients 科技报告
报告编号: NASA-TM-X-59742. 出版年: 1967
作者:  Heyson, H. H.
收藏  |  浏览/下载:7/0  |  提交时间:2019/11/30
WAKES  WALL FLOW  WIND TUNNELS  AERODYNAMIC LOADS  CORRECTION  PRESSURE GRADIENTS  REYNOLDS NUMBER  SUPPORT INTERFERENCE  
Heat Transmission in the Boundary Layer 科技报告
报告编号: NACA-TM-1229. 出版年: 1949
作者:  Kalikhman, L. E.
收藏  |  浏览/下载:12/0  |  提交时间:2019/11/30
BOUNDARY LAYERS  HEAT TRANSMISSION  NUMERICAL ANALYSIS  PRANDTL NUMBER  TEMPERATURE DISTRIBUTION  COMPRESSIBILITY  COEFFICIENT OF FRICTION  INDEPENDENT VARIABLES  WALL FLOW  VELOCITY DISTRIBUTION  
Compression Shocks of Detached Flow 科技报告
报告编号: NACA-TM-1150. 出版年: 1947
作者:  Eggink
收藏  |  浏览/下载:4/0  |  提交时间:2019/11/30
SHOCK WAVES  SEPARATED FLOW  WALL FLOW  FLOW DISTRIBUTION  
Heat-transfer coefficients for air flowing in round tubes, in rectangular ducts, and around finned cylinders 科技报告
报告编号: NACA-WR-W-108, NACA-ARR-4F28. 出版年: 1945
作者:  Drexel, Rober E;  Mcadams, William H
收藏  |  浏览/下载:11/0  |  提交时间:2019/11/30
AIR FLOW  DUCTED FLOW  HEAT TRANSFER  CIRCULAR TUBES  FINNED BODIES  CYLINDERS  RECTANGLES  CONVECTIVE FLOW  HEAT TRANSFER COEFFICIENTS  PRESSURE DROP  LAMINAR FLOW  TURBULENT FLOW  WALL TEMPERATURE  REYNOLDS NUMBER  BLOWERS  EQUATIONS  SURFACE ROUGHNESS  
Heat-transfer tests of aqueous ethylene glycol solutions in an electrically heated tube 科技报告
报告编号: NACA-WR-E-136, NACA-ARR-E5F07. 出版年: 1945
作者:  Bernardo, Everett;  Eian, Carroll S
收藏  |  浏览/下载:6/0  |  提交时间:2019/11/30
COOLANTS  HEAT TRANSFER  ETHYLENE COMPOUNDS  GLYCOLS  WATER  MIXTURES  HEAT TRANSFER COEFFICIENTS  TUBE HEAT EXCHANGERS  LIQUID FLOW  FLOW VELOCITY  REYNOLDS NUMBER  WALL TEMPERATURE  TESTS  LIQUID COOLING  AIRCRAFT ENGINES