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Optimization of Betulinic Acid analogs for T-type calcium channel inhibition for non-addictive relief of chronic pain 项目
项目编号: 1R41DA050364-01. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-2020
负责人:  KHANNA, RAJESH
收藏  |  浏览/下载：37/0  |  提交时间：2021/08/12
Absence of pain sensation  addiction  Affect  Afferent Neurons  American  Amitriptyline  Analgesics  analog  Antidepressive Agents  Arizona  Axon  Baclofen  base  Betulinic Acid  Biological Assay  biophysical properties  Calcium  Calcium Channel Blockers  Calcium Channel Inhibition  cancer pain  Cancer Patient  cancer survival  cancer therapy  Cell-Mediated Cytolysis  Cells  central sensitization  chemotherapeutic agent  chemotherapy  Chemotherapy-induced peripheral neuropathy  Chemotherapy-Oncologic Procedure  Chronic  chronic pain  chronic pain relief  chronic painful condition  Clinical  Clinical Trials  Complex  compliance behavior  Complication  counterscreen  Coupled  design  dorsal horn  Dose-Limiting  drug discovery  Drug Kinetics  Drug Targeting  duloxetine  Dysesthesias  effective therapy  Effectiveness  Esthesia  Feeling  Fiber  G-Protein-Coupled Receptors  Human  improved  In Vitro  in vivo  Indigenous  inhibitor/antagonist  Ion Channel  Laboratories  Lavandula  Lead  Malignant Neoplasms  Mediating  Mediator of activation protein  Medical  Medicinal Plants  meetings  Modeling  Muscle relaxants  Natural Products  Neuraxis  neuronal excitability  Neurons  Neuropathy  neurotoxic  neurotoxicity  neurotransmission  non-opioid analgesic  Norepinephrine  novel  novel therapeutics  Numbness  Opiate Addiction  Opioid  opioid misuse  Opioid Receptor  opioid sparing  opioid use  Oral  Paclitaxel  Pain  Pain management  pain model  pain relief  pain signal  painful neuropathy  Paresthesia  Pathogenesis  Pathway interactions  Peripheral  Peripheral Nerves  Peripheral Nervous System  Peripheral Nervous System Diseases  Pharmaceutical Preparations  Pharmacology  Pharmacotherapy  Phase  Plants  Platinum Compounds  preclinical study  Prevalence  Property  Protein Isoforms  Proteins  Quality of life  Rattus  Regimen  Regulation  reuptake  Role  Safety  screening  Sensory  sensory stimulus  Serotonin  Shock  side effect  Site  small molecule  somatosensory  Southwestern United States  Specificity  Spinal  Spinal Cord  Spinal Ganglia  Structure  success  Survival Rate  synaptic function  T-Type Calcium Channels  taxane  Testing  Tissues  Translating  Treatment Protocols  Universities  venlafaxine  Vinca Alkaloids  voltage  Work  
Mu-Opioid Receptor - pAKT Signaling in the Ventral Tegmental Area is Critical for the Behavioral and Cellular Consequences of Social Stress 学位论文
学位授予机构: Johnston, Caitlin Elizabeth (Author), Hammer, Ronald P. (Advisor), Nikulina, Ella M. (Advisor), Neisewander, Janet L. (Committee member), Wu, Jie (Committee member), Olive, Michael F. (Committee member), Arizona State University (Publisher). 出版年: 2015
作者:  [null]
收藏  |  浏览/下载：11/0  |  提交时间：2019/11/29
Neurosciences  Molecular biology  Psychology  AKT  Amphetamine  BDNF  Mu-opioid receptor  Sensitization  Stress  
Allergic Sensitization in Healthy School Children in Kuwait: An Emerging Public Health Concern 期刊论文
发表期刊: KUWAIT MEDICAL JOURNAL. 出版年: 2009, 卷号: 41, 期号: 4, 页码: 317-321
作者:  Al-Mousawi, Mahdi;  Ramadan, Massuma Ali G.;  Taher, Mahmood Mahdi;  Behbehani, Nasser
收藏  |  浏览/下载：13/0  |  提交时间：2019/11/28
allergic sensitization  Kuwait  public health  school children  skin prick test  
Allergen sensitization in children with asthma and rhinitis: marked variations related to age and microgeographical factors 期刊论文
发表期刊: ALLERGOLOGIA ET IMMUNOPATHOLOGIA. 出版年: 2008, 卷号: 36, 期号: 3, 页码: 128-133
作者:  Moral, L.;  Roig, M.;  Garde, J.;  Alos, A.;  Toral, T.;  Fuentes, M. J.
收藏  |  浏览/下载：6/0  |  提交时间：2019/11/28
aeroallergens  Alternaria  asthma  childhood  coast  mites  rhinitis  Salsola  sensitization  
Asthma and sensitization in a community with low indoor allergen levels and low pet-keeping frequency 期刊论文
发表期刊: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 出版年: 2004, 卷号: 114, 期号: 6, 页码: 1389-1394
作者:  Al-Mousawi, MSH;  Lovel, H;  Behbehani, N;  Arifhodzic, N;  Woodcock, A;  Custovic, A
收藏  |  浏览/下载：28/0  |  提交时间：2019/11/28
asthma  sensitization  domestic pets  allergen exposure  
Asthma in the desert: spectrum of the sensitizing aeroallergens 期刊论文
发表期刊: ALLERGY. 出版年: 2000, 卷号: 55, 期号: 2, 页码: 157-162
作者:  Ezeamuzie, CI;  Thomson, MS;  Al-Ali, S;  Dowaisan, A;  Khan, M;  Hijazi, Z
收藏  |  浏览/下载：13/0  |  提交时间：2019/11/28
aeroallergens  allergy  asthma  desert  IgE  Kuwait  sensitization  
IgE-mediated sensitization to mould allergens among patients with allergic respiratory diseases in a desert environment 期刊论文
发表期刊: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 出版年: 2000, 卷号: 121, 期号: 4, 页码: 300-307
作者:  Ezeamuzie, CI;  Al-Ali, A;  Khan, M;  Hijazi, Z;  Dowaisan, A;  Thomson, MS;  Georgi, J
收藏  |  浏览/下载：31/0  |  提交时间：2019/11/28
asthma  moulds  sensitization  IgE  desert  Kuwait  
Prevalence of allergic sensitization to inhalant allergens among blood donors in Kuwait - a desert country 期刊论文
发表期刊: ALLERGY. 出版年: 1997, 卷号: 52, 期号: 12, 页码: 1194-1200
作者:  Ezeamuzie, CI;  Al-Mousawi, M;  Dashti, H;  Al-Bashir, A;  Al-Hage, M;  Al-Ali, S
收藏  |  浏览/下载：11/0  |  提交时间：2019/11/28
allergy  atopy  Kuwaiti  prevalence  Phadiatop  sensitization