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Project 1 - Disruption of CpG island-mediated gene regulation and chromatin architecture in progeria and aging 项目
项目编号: 5P20GM104318-08. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2019-
负责人:  BECK, SAMUEL
收藏  |  浏览/下载:25/0  |  提交时间:2021/08/12
Address  Age of Onset  age related  Aging  Architecture  Atherosclerosis  Biological  Biology of Aging  Biomedical Research  Blindness  Cardiac Myocytes  Cell Differentiation process  Cells  Chromatin  Chromosome Mapping  Comparative Biology  CpG Islands  CRISPR/Cas technology  Cytosine  Data Set  de novo mutation  Defect  Degenerative Disorder  Dinucleoside Phosphates  Disease  DNA  DNA Damage  DNA Repair  Economics  Elements  epigenetic regulation  Euchromatin  Fatty Liver  Fluorescent in Situ Hybridization  Frequencies  Gene Expression  Gene Expression Regulation  Genes  Genetic  Genetic Transcription  genome editing  genome-wide  Genomic Instability  Goals  Guanine  Hair  Hepatocyte  Heterochromatin  Impairment  induced pluripotent stem cell  innovation  inorganic phosphate  insight  Lamin Type A  Lamins  Life  Life Expectancy  Link  Mediating  Meta-Analysis  Modeling  Molecular  Morphology  mRNA sequencing  Musculoskeletal  Mutation  Natural regeneration  Nuclear  Nuclear Lamin  Nuclear Lamina  Pathology  Patients  Peripheral  Physiological  Predisposition  prevent  Process  Progeria  promoter  Property  Proteins  Psyche structure  Public Health  Regulation  Resources  response  restoration  Skin  Structural Protein  Symptoms  Testing  therapy development  tissue repair  Tissues  Undifferentiated  
Effects of Age and Size on Xylem Phenology in Two Conifers of Northwestern China 期刊论文
发表期刊: FRONTIERS IN PLANT SCIENCE. 出版年: 2018, 卷号: 8
作者:  Zeng, Qiao;  Rossi, Sergio;  Yang, Bao
收藏  |  浏览/下载:26/0  |  提交时间:2019/11/29
cambium activity  cell differentiation  Juniperus przewalskii  Pinus tabulaeformis  radial growth  wood anatomy  xylogenesis  
In vitro induction of human embryonal carcinoma differentiation by a crude extract of Rhazya stricta 期刊论文
发表期刊: BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE. 出版年: 2017, 卷号: 17
作者:  Alagrafi, Faisal S.;  Alawad, Abdullah O.;  Abutaha, Nael M.;  Nasr, Fahd A.;  Alhazzaa, Othman A.;  Alharbi, Sultan N.;  Alkhrayef, Mohammad N.;  Hammad, Mohamed;  Alhamdan, Ziyad A.;  Alenazi, Abdullah D.;  Wadaan, Mohammad A.
收藏  |  浏览/下载:48/0  |  提交时间:2019/11/29
Differentiation  NTERA-2 cell lines  Retinoic acid  Rhazya stricta  Plant extract  
Longitudinal zonation pattern in Arabidopsis root tip defined by a multiple structural change algorithm 期刊论文
发表期刊: ANNALS OF BOTANY. 出版年: 2016, 卷号: 118, 期号: 4, 页码: 763-776
作者:  Pacheco-Escobedo, Mario A.;  Ivanov, Victor B.;  Ransom-Rodriguez, Ivan;  Arriaga-Mejia, German;  Avila, Hibels;  Baklanov, Ilya A.;  Pimentel, Arturo;  Corkidi, Gabriel;  Doerner, Peter;  Dubrovsky, Joseph G.;  Alvarez-Buylla, Elena R.;  Garay-Arroyo, Adriana
收藏  |  浏览/下载:19/0  |  提交时间:2019/11/29
Arabidopsis thaliana  cell differentiation  cell proliferation  proliferation domain  transition domain  elongation zone  root apical meristem  longitudinal zonation pattern  critical size of dividing cells  XAANTAL1  multiple structural change model  breakpoints  
Xylem tissue specification, patterning, and differentiation mechanisms 期刊论文
发表期刊: JOURNAL OF EXPERIMENTAL BOTANY. 出版年: 2013, 卷号: 64, 期号: 1, 页码: 11-31
作者:  Schuetz, Mathias;  Smith, Rebecca;  Ellis, Brian
收藏  |  浏览/下载:13/0  |  提交时间:2019/11/29
Arabidopsis  fibre  secondary cell wall  lignification  tracheophytes  tracheary element  xylem specification  xylem differentiation  
Normal male sexual differentiation and aetiology of disorders of sex development 期刊论文
发表期刊: BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM. 出版年: 2011, 卷号: 25, 期号: 2, 页码: 221-238
作者:  Rey, Rodolfo A.;  Grinspon, Romina P.
收藏  |  浏览/下载:16/0  |  提交时间:2019/11/29
Sexual Development  Leydig cell  Sertoli cell  Androgens  Anti-Mullerian hormone  Insulin-like factor 3  Sex Differentiation Disorders  Hypogonadism  Gonadal Dysgenesis  Steroid synthesis defects  Androgen Insensitivity Syndrome  Persistent Mullerian Duct Syndrome  Urogenital abnormalities  
Physiological Unfolded Protein Response Regulated by OASIS Family Members, Transmembrane bZIP Transcription Factors 期刊论文
发表期刊: IUBMB LIFE. 出版年: 2011, 卷号: 63, 期号: 4, 页码: 233-239
作者:  Kondo, Shinichi;  Saito, Atsushi;  Asada, Rie;  Kanemoto, Soshi;  Imaizumi, Kazunori
收藏  |  浏览/下载:11/0  |  提交时间:2019/11/29
endoplasmic reticulum stress  cell differentiation  unfolded protein response  transmembrane transcription factor  secretory cells  
Desert Hedgehog诱导大鼠胚胎中脑神经前体细胞定向分化为多巴胺能神经元 期刊论文
出版年: 2009, 卷号: 29, 期号: 4, 页码: 360-365
作者:  杨彩侠;  赵焕英;  赵春礼;  刘靖;  徐群渊;  高福禄
收藏  |  浏览/下载:22/0  |  提交时间:2019/11/29
Desert Hedgehog  Desert Hedgehog  neural progenitor cell  dopaminergic neuron  differentiation  rat