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Optimization of Betulinic Acid analogs for T-type calcium channel inhibition for non-addictive relief of chronic pain 项目
项目编号: 1R41DA050364-01. 资助机构: US-NIH(美国国立卫生研究院). 起止日期: 2019-2020
负责人:  KHANNA, RAJESH
收藏  |  浏览/下载:37/0  |  提交时间:2021/08/12
Absence of pain sensation  addiction  Affect  Afferent Neurons  American  Amitriptyline  Analgesics  analog  Antidepressive Agents  Arizona  Axon  Baclofen  base  Betulinic Acid  Biological Assay  biophysical properties  Calcium  Calcium Channel Blockers  Calcium Channel Inhibition  cancer pain  Cancer Patient  cancer survival  cancer therapy  Cell-Mediated Cytolysis  Cells  central sensitization  chemotherapeutic agent  chemotherapy  Chemotherapy-induced peripheral neuropathy  Chemotherapy-Oncologic Procedure  Chronic  chronic pain  chronic pain relief  chronic painful condition  Clinical  Clinical Trials  Complex  compliance behavior  Complication  counterscreen  Coupled  design  dorsal horn  Dose-Limiting  drug discovery  Drug Kinetics  Drug Targeting  duloxetine  Dysesthesias  effective therapy  Effectiveness  Esthesia  Feeling  Fiber  G-Protein-Coupled Receptors  Human  improved  In Vitro  in vivo  Indigenous  inhibitor/antagonist  Ion Channel  Laboratories  Lavandula  Lead  Malignant Neoplasms  Mediating  Mediator of activation protein  Medical  Medicinal Plants  meetings  Modeling  Muscle relaxants  Natural Products  Neuraxis  neuronal excitability  Neurons  Neuropathy  neurotoxic  neurotoxicity  neurotransmission  non-opioid analgesic  Norepinephrine  novel  novel therapeutics  Numbness  Opiate Addiction  Opioid  opioid misuse  Opioid Receptor  opioid sparing  opioid use  Oral  Paclitaxel  Pain  Pain management  pain model  pain relief  pain signal  painful neuropathy  Paresthesia  Pathogenesis  Pathway interactions  Peripheral  Peripheral Nerves  Peripheral Nervous System  Peripheral Nervous System Diseases  Pharmaceutical Preparations  Pharmacology  Pharmacotherapy  Phase  Plants  Platinum Compounds  preclinical study  Prevalence  Property  Protein Isoforms  Proteins  Quality of life  Rattus  Regimen  Regulation  reuptake  Role  Safety  screening  Sensory  sensory stimulus  Serotonin  Shock  side effect  Site  small molecule  somatosensory  Southwestern United States  Specificity  Spinal  Spinal Cord  Spinal Ganglia  Structure  success  Survival Rate  synaptic function  T-Type Calcium Channels  taxane  Testing  Tissues  Translating  Treatment Protocols  Universities  venlafaxine  Vinca Alkaloids  voltage  Work  
Empirical evaluation of the conceptual model underpinning a regional aquatic long-term monitoring program using causal modelling 期刊论文
发表期刊: ECOLOGICAL INDICATORS. 出版年: 2015, 卷号: 50, 页码: 8-23
作者:  Irvine, Kathryn M.;  Miller, Scott W.;  Al-Chokhachy, Robert K.;  Archer, Eric K.;  Roper, Brett B.;  Kershner, Jeffrey L.
收藏  |  浏览/下载:12/0  |  提交时间:2019/11/29
Adaptive monitoring  Grazing  Heterogeneous landscapes  Long-term monitoring  Mediator  Moderator  Macroinvertebrates  Path analysis  Roads  Sedimentation  
The Role of Mediator in White-Opaque Switching 学位论文
学位授予机构: Dartmouth College. 出版年: 2014
作者:  Zhang, Anda
收藏  |  浏览/下载:12/0  |  提交时间:2019/11/29
Candida albicans  Epigenetic switch  Mediator  Transcription regulation  White-opaque switching  
Actions of lignocellulolytic enzymes on Abies grandis(grand fir) wood for application in biofuel production 学位论文
出版年: 2010
作者:  Cherdchim;Banyat
收藏  |  浏览/下载:14/0  |  提交时间:2019/11/29
000 Allgemeines  Wissenschaft  Forest Sciences and Forest Ecology  Abies grandis  Armillaria mellea  Heterobasidion annosum  Heterobasidion parviporum  Pleurotus ostreatus  Trametes versicolor  Coniophora puteana  Biodegradation  Cell wall modification  Urea formaldehyde  Ammonium sulphate  Mass loss  Area fraction  Stained cell wall  Cell wall area  Latewood  Earlywood  Oxidative enzyme  MBTH  Laccase-mediator  Manganese peroxidase  Butylhydroxytoluol  Carbon  Chromatography fraction  Coprinopsis cinerea  Decay fungi  1  4-dihydroxybenzene  P-benzochinone  3  5-di-tertbut-4-hydroxy-toluene  GC-MS analysis  Gel electrophoresis  Growth inhibition  4-hydroxy cinnamic acid  Laccase induction  Nitrogen  Phenolic compounds  P-coumaric acid  Wood extraction  Wood extractives  Biofuels  Chemical pretreatment  Physico-chemical pretreatment  Biological pretreatment  Microwave irradiation  Liquid acid  Rate of production of glucose  Kinetic curve of production of glucose  Influence of wood extractive  Influence of phenolic compound  Abies grandis  Armillaria mellea  Heterobasidion annosum  Heterobasidion parviporum  Pleurotus ostreatus  Trametes versicolor  Coniophora puteana  Biodegradation  Cell wall modification  Urea formaldehyde  Ammonium sulphate  Mass loss  Area fraction  Stained cell wall  Cell wall area  Latewood  Earlywood  Oxidative enzyme  MBTH  Laccase-mediator  Manganese peroxidase  Butylhydroxytoluol  Carbon  Chromatography fraction  Coprinopsis cinerea  Decay fungi  1  4-dihydroxybenzene  P-benzochinone  3  5-di-tertbut-4-hydroxy-toluene  GC-MS analysis  Gel electrophoresis  Growth inhibition  4-hydroxy cinnamic acid  Laccase induction  Nitrogen  Phenolic compounds  P-coumaric acid  Wood extraction  Wood extractives  Biofuels  Chemical pretreatment  Physico-chemical pretreatment  Biological pretreatment  Microwave irradiation  Liquid acid  Rate of production of glucose  Kinetic curve of production of glucose  Influence of wood extractive  Influence of phenolic compound  48.46 Holz  YQ 000: Forstbotanik  
中红侧沟茧蜂滞育诱导和滞育茧的冷藏 期刊论文
发表期刊: 昆虫学报. 出版年: 2005, 卷号: 48, 期号: 5, 页码: 655-659
作者:  浑之英;  王德安;  路子云;  潘文亮
收藏  |  浏览/下载:10/0  |  提交时间:2019/11/29
Microplitis mediator  diapause induction  photoperiod  temperature  diapause cocoons  cold storage