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Apply an imaging flow cytometry method to screen chemical libraries for identifying and repurposing novel drugs against coccidioidomycosis 项目
项目编号: 1R21AI149015-01. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2020-2021
负责人:  HUNG, CHIUNG YU
收藏  |  浏览/下载：26/0  |  提交时间：2021/08/12
acute infection  Adverse effects  Affect  Americas  Amphotericin B  Animals  Antifungal Agents  Antimicrobial Resistance  Area  base  Biological Assay  Caliber  Caspofungin  Cell Membrane Permeability  Cell Wall  Cells  chemotherapy  Clinical  Coccidioides  Coccidioides immitis  Coccidioides posadasii  Coccidioidomycosis  Communities  Containment  Contracts  cost  Cryptococcus  Cryptococcus neoformans  Cytochrome P450  Cytology  cytotoxicity  Data  Databases  desert fever  Development  Diagnosis  Disease  Dose  drug development  Drug usage  drug use screening  Flow Cytometry  Fluconazole  follow-up  fungus  Goals  Government  Growth  Hand  Human  Hyphae  Image  In Vitro  in vivo  Incubated  indexing  Infection  Inhalation  insight  Lead  Legal patent  Libraries  Life Cycle Stages  Lower respiratory tract structure  Lung  Lung diseases  Medical  Medical Research  Meningitis  Methods  Mexico  Microscope  Morphology  Motivation  Mycoses  Neuraxis  novel  novel strategies  novel therapeutics  off-patent  pathogen  pathogenic fungus  Patients  Pharmaceutical Preparations  Pharmacology  Phase IV Clinical Trials  Phenotype  Pneumonia  preclinical development  prevent  Process  Property  Reporting  Reproduction spores  Research Personnel  resistant strain  Resolution  screening  small molecule libraries  Soil  South America  Southwestern United States  Speed  success  Symptoms  synergism  Techniques  Testing  The science of Mycology  Time  Toxic effect  United States  United States National Institutes of Health  Vaccines  
Antifungal Activity in Compounds from the Australian Desert Plant Eremophila alternifolia with Potency Against Cryptococcus spp. 期刊论文
发表期刊: ANTIBIOTICS-BASEL. 出版年: 2019, 卷号: 8, 期号: 2
作者:  Hossain, Mohammed A.;  Biva, Israt J.;  Kidd, Sarah E.;  Whittle, Jason D.;  Griesser, Hans J.;  Coad, Bryan R.
收藏  |  浏览/下载：13/0  |  提交时间：2019/11/29
Diterpenoids  antifungal  wound healing  serrulatane  fungi  Eremophila  Cryptococcus  disk diffusion  broth microdilution  
Fantastic yeasts and where to find them: the discovery of a predominantly clonal Cryptococcus deneoformans population in Saudi Arabian soils 期刊论文
发表期刊: FEMS MICROBIOLOGY ECOLOGY. 出版年: 2019, 卷号: 95, 期号: 9
作者:  Samarasinghe, Himeshi;  Aljohani, Renad;  Jimenez, Carlene;  Xu, Jianping
收藏  |  浏览/下载：11/0  |  提交时间：2019/11/29
Cryptococcus neoformans  Saudi Arabia  soil yeast  MLST  diversity  
Survival of Extremophilic Yeasts in the Stratospheric Environment during Balloon Flights and in Laboratory Simulations 期刊论文
发表期刊: APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 出版年: 2018, 卷号: 84, 期号: 23
作者:  Pulschen, Andre Arashiro;  de Araujo, Gabriel Guarany;  Souza Ramosde Carvalho, Ana Carolina;  Cerini, Maria Fernanda;  Fonseca, Lucas de Mendonca;  Galante, Douglas;  Rodrigues, Fabio
收藏  |  浏览/下载：15/0  |  提交时间：2019/11/29
yeasts  Naganishia friedmannii  Cryptococcus  aerobiology  astrobiology  Atacama  extremophiles  stratosphere  UV light  
The ecology of extremophile yeasts 会议论文
会议名称: Conference on Instruments, Methods, and Missions for Astrobiology. 会议地点: SAN DIEGO, CA. 会议日期: JUL 20-22, 1998
作者:  Vishniac, HS
收藏  |  浏览/下载：6/0  |  提交时间：2019/12/07
Antarctica  Cryptococcus  deserts  freeze-thaw  halotolerance  osmotolerance  oligophile  psychrophile  xerotolerance  
KILLER FACTOR AS A MECHANISM OF INTERFERENCE COMPETITION IN YEASTS ASSOCIATED WITH CACTI 期刊论文
发表期刊: ECOLOGY. 出版年: 1992, 卷号: 73, 期号: 1, 页码: 54-67
作者:  GANTER, PF;  STARMER, WT
收藏  |  浏览/下载：12/0  |  提交时间：2019/11/28
CACTI  CRYPTOCOCCUS-CEREANUS  INTERFERENCE COMPETITION  KILLER FACTOR  PICHIA-ANTILLENSIS  P-CACTOPHILA  P-KLUYVERI  P-OPUNTIAE  P-THERMOTOLERANS  SENSITIVITY  SONORAN DESERT  YEAST COMMUNITIES