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Micropreparative isolation and NMR structure elucidation of metabolites of the drug candidate 1-isopropyl-4-(4-isopropylphenyl)-6-(prop-2-yn-1-yloxy) quinazolin-2(1H)-one from rat bile and urine 期刊论文
发表期刊: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 出版年: 2015, 卷号: 989, 页码: 1-10
作者:  Blanz, Joachim;  Delemonte, Thierry;  Pearson, David;  Luneau, Alexandre;  Ritzau, Michael;  Gertsch, Werner;  Ramstein, Philippe;  Dayer, Jerome;  Desrayaud, Sandrine;  Braun, Elisabeth;  Aichholz, Reiner
收藏  |  浏览/下载:11/0  |  提交时间:2019/11/29
Biotransformation  Drug metabolism  Metabolite identification  Micropreparative isolation  HPLC-MS-SPE-NMR  
Biotransformation of (-)-(10E,15S)-10,11-Dehydrocurvularin 期刊论文
发表期刊: NATURAL PRODUCT COMMUNICATIONS. 出版年: 2015, 卷号: 10, 期号: 7, 页码: 1277-1278
作者:  Deng, Zhangshuang;  Deng, Aiping;  Luo, Dan;  Gong, Dachun;  Zou, Kun;  Peng, Yan;  Guo, Zhiyong
收藏  |  浏览/下载:11/0  |  提交时间:2019/11/29
Biotransformation  Dehydrocurvularin  Curvularin  Cytotoxicity  
Functional characterization of cytochromes P450 2B from the desert woodrat Neotoma lepida 期刊论文
发表期刊: TOXICOLOGY AND APPLIED PHARMACOLOGY. 出版年: 2014, 卷号: 274, 期号: 3, 页码: 393-401
作者:  Wilderman, P. Ross;  Jang, Hyun-Hee;  Malenke, Jael R.;  Salib, Mariam;  Angermeier, Elisabeth;  Lamime, Sonia;  Dearing, M. Denise;  Halpert, James R.
收藏  |  浏览/下载:15/0  |  提交时间:2019/11/29
Biotransformation  Woodrats  Cytochrome P450  Juniper  Detoxification  
Adaptation strategies of soil biodiversity (earthworms) to pesticides : mechanisms in play and ecosystemic cost assessment Potentiel d'adaptation des lombricidés aux pollutions environnementales résiduelles établies en paysage agricole : mécanismes en jeu et coûts à l'écosystème 学位论文
出版年: 2014
作者:  Givaudan;Nicolas
收藏  |  浏览/下载:13/0  |  提交时间:2019/11/29
Aporrectodea caliginosa  Pesticides  Biotransformation  Stress oxidatif  Adaptation  Epoxiconazole  Ressources énergétiques  Profil métabolique  Bioturbation du sol  Traits d’histoire de vie  Cocons  Croissance  Contamination des sols  Aporrectodea caliginosa  Pesticides  Biotransformation  Oxidative stress  Adaptation  Land-Use  Epoxiconazole  Energy storage  Metabolomic profile  Soil bioturbation  Life history traits  Cocoons  Growth  Pesticides  Soil organic contamination  
Hepatic gene expression in herbivores on diets with natural and novel plant secondary compounds 期刊论文
发表期刊: PHYSIOLOGICAL GENOMICS. 出版年: 2013, 卷号: 45, 期号: 17, 页码: 774-785
作者:  Magnanou, Elodie;  Malenke, Jael R.;  Dearing, M. Denise
收藏  |  浏览/下载:7/0  |  提交时间:2019/11/29
biotransformation  gene expression  PSCs  liver  microarray  woodrat  
Expression of biotransformation genes in woodrat (Neotoma) herbivores on novel and ancestral diets: identification of candidate genes responsible for dietary shifts 期刊论文
发表期刊: MOLECULAR ECOLOGY. 出版年: 2009, 卷号: 18, 期号: 11, 页码: 2401-2414
作者:  Magnanou, E.;  Malenke, J. R.;  Dearing, M. D.
收藏  |  浏览/下载:14/0  |  提交时间:2019/11/28
biotransformation  creosote  detoxification  juniper  woodrats  
Seasonal seawater temperature as the major determinant for populations of culturable bacteria in the sediments of an intact mangrove in an arid region 期刊论文
发表期刊: FEMS MICROBIOLOGY ECOLOGY. 出版年: 2006, 卷号: 55, 期号: 2, 页码: 311-321
作者:  Gonzalez-Acosta, B;  Bashan, Y;  Hernandez-Saavedra, NY;  Ascencio, F;  De la Cruz-Aguero, G
收藏  |  浏览/下载:8/0  |  提交时间:2019/11/28
bacterial biotransformation  bacteria population dynamics  mangrove  sediments  
Studies on Bacillus stearothermophilus Part II. Transformation of progesterone 期刊论文
发表期刊: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 出版年: 2002, 卷号: 82, 期号: 2-3, 页码: 251-256
作者:  Al-Awadi, S;  Afzal, M;  Oommen, S
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/28
microbial steroid biotransformation  hydroxyprogesterone  thermophilic  NMR  Bacillus stearothermophilus  
Studies on Bacillus stearothermophilus. Part 1. Transformation of progesterone to a new metabolite 9,10-seco-4-pregnene-3,9,20-trione 期刊论文
发表期刊: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 出版年: 2001, 卷号: 78, 期号: 5, 页码: 493-498
作者:  Al-Awadi, S;  Afzal, M;  Oommen, S
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/28
microbial steroid biotransformation  hydroxyprogesterone  B-seco-compound  NMR  Bacillus stearothermophilus