干旱区生态环境知识资源中心(Arid): Studies on Bacillus stearothermophilus Part II. Transformation of progesterone

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DOI	10.1016/S0960-0760(02)00183-8
	Studies on Bacillus stearothermophilus Part II. Transformation of progesterone
	Al-Awadi, S; Afzal, M; Oommen, S
通讯作者	Al-Awadi, S
来源期刊	JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
ISSN	0960-0760
出版年	2002
卷号	82 期号:2-3 页码:251-256
英文摘要	Bacillus stearothermophilus, a thermophilic bacterium isolated from Kuwaiti desert, when incubated with exogenous progesterone for 10 days at 65degreesC produced two new dihydroxy isomers of progesterone, and two known compounds, 5alpha-pregnane-3,6,20-trione and 6-dehydroprogesterone, along with the earlier reported monohydroxylated metabolites and a B-Seco compound. The two new dihydroxy compounds were identified as 6alpha,20alpha-dihydroxyprogesterone and 6beta,20alpha-dihydroxyprogesterone. These metabolites were purified by TLC and HPLC followed by their identification through H-1, C-13 NMR and other spectroscopic data. (C) 2002 Elsevier Science Ltd. All rights reserved.
英文关键词	microbial steroid biotransformation hydroxyprogesterone thermophilic NMR Bacillus stearothermophilus
类型	Article
语种	英语
国家	Kuwait
收录类别	SCI-E
WOS记录号	WOS:000180029400010
WOS关键词	MICROBIAL TRANSFORMATIONS ; NEUROACTIVE STEROIDS
WOS类目	Biochemistry & Molecular Biology ; Endocrinology & Metabolism
WOS研究方向	Biochemistry & Molecular Biology ; Endocrinology & Metabolism
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/143259
作者单位	(1)Kuwait Univ, Fac Sci, Dept Biol Sci, Biochem Program, Safat 13060, Kuwait
推荐引用方式 GB/T 7714	Al-Awadi, S,Afzal, M,Oommen, S. Studies on Bacillus stearothermophilus Part II. Transformation of progesterone[J],2002,82(2-3):251-256.
APA	Al-Awadi, S,Afzal, M,&Oommen, S.(2002).Studies on Bacillus stearothermophilus Part II. Transformation of progesterone.JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY,82(2-3),251-256.
MLA	Al-Awadi, S,et al."Studies on Bacillus stearothermophilus Part II. Transformation of progesterone".JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 82.2-3(2002):251-256.