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Isocyanate derivatization coupled with phospholipid removal microelution-solid phase extraction for the simultaneous quantification of (S)-metoprolol and (S)-alpha-hydroxymetoprolol in human plasma with LC-MS/MS 期刊论文
发表期刊: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 出版年: 2021, 卷号: 204
作者:  Meloche, Maxime;  Jutras, Martin;  St-Jean, Isabelle;  de Denus, Simon;  Leclair, Gregoire
收藏  |  浏览/下载:11/0  |  提交时间:2021/11/19
Metoprolol  Phospholipid removal microelution-solid phase extraction  Isocyanate derivatization  LC-MS/MS  Chiral assay  
Development and validation of a liquid chromatography coupled to tandem mass spectrometry method for the simultaneous quantification of five analgesics and sedatives, and six of their active metabolites in human plasma: Application to a clinical study on the determination of neurological death in the intensive care unit 期刊论文
发表期刊: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 出版年: 2020, 卷号: 190
作者:  Jutras, Martin;  Williamson, David;  Chasse, Michael;  Leclair, Gregoire
收藏  |  浏览/下载:15/0  |  提交时间:2021/01/07
Method validation  Liquid chromatography coupled to tandem mass spectrometry  Human plasma  Sedatives  Analgesics  Neurological death