干旱区生态环境知识资源中心(Arid): Poisonings in ruminants by Cenostigma pyramidale (Tul.) Gagnon & GP Lewis (Fabaceae): A mini-review of teratogenic potential and phytochemical evidence

Arid

DOI	10.1016/j.toxicon.2024.107794
	Poisonings in ruminants by Cenostigma pyramidale (Tul.) Gagnon & GP Lewis (Fabaceae): A mini-review of teratogenic potential and phytochemical evidence
	Bezerra, Jose Jailson Lima; Lucena, Ricardo Barbosa
通讯作者	Lucena, RB
来源期刊	TOXICON
ISSN	0041-0101
EISSN	1879-3150
出版年	2024
卷号	246
英文摘要	Teratogenic plants can be found in pastures in different parts of the world and represent a threat to the reproduction of ruminants. In the northeast region of Brazil, several studies have indicated that Cenostigma pyramidale (Tul.) Gagnon & G.P.Lewis is one of the main poisonous plants that causes reproductive problems in sheep and goats. In this context, the present study reviewed spontaneous and experimental poisonings reports by C. pyramidale in sheep and goats, as well as analyzing the phytochemical evidence related to this species. The scientific documents were retrieved from different databases and, after applying the selection criteria, a total of 16 articles published between 2000 and 2024 were included in this review. Cenostigma pyramidale causes embryonic loss, abortion, and congenital malformations in pregnant sheep and goats in the Brazilian semi-arid region. The main malformations observed in newborn animals are arthrogryposis, scoliosis, micrognathia, multiple skull deformities, cleft palate, and brachygnathism. Many secondary metabolites have already been isolated from C. pyramidale, however, to date, no evidence has been found regarding the possible teratogenic compounds that occur in this plant. From this perspective, new phytochemical studies are necessary to help unravel the mechanisms of action of embryotoxic agents from C. pyramidale.
英文关键词	Plant poisonings Abortions Congenital malformations Embryotoxic Sheep Goats
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:001251858100001
WOS关键词	POINCIANELLA-PYRAMIDALIS ; REPRODUCTIVE LOSSES ; CONGENITAL-MALFORMATIONS ; MIMOSA-TENUIFLORA ; POISONOUS PLANTS ; INGESTION ; TOXICITY ; ABORTION ; LEAVES ; GOATS
WOS类目	Pharmacology & Pharmacy ; Toxicology
WOS研究方向	Pharmacology & Pharmacy ; Toxicology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/405806
推荐引用方式 GB/T 7714	Bezerra, Jose Jailson Lima,Lucena, Ricardo Barbosa. Poisonings in ruminants by Cenostigma pyramidale (Tul.) Gagnon & GP Lewis (Fabaceae): A mini-review of teratogenic potential and phytochemical evidence[J],2024,246.
APA	Bezerra, Jose Jailson Lima,&Lucena, Ricardo Barbosa.(2024).Poisonings in ruminants by Cenostigma pyramidale (Tul.) Gagnon & GP Lewis (Fabaceae): A mini-review of teratogenic potential and phytochemical evidence.TOXICON,246.
MLA	Bezerra, Jose Jailson Lima,et al."Poisonings in ruminants by Cenostigma pyramidale (Tul.) Gagnon & GP Lewis (Fabaceae): A mini-review of teratogenic potential and phytochemical evidence".TOXICON 246(2024).