干旱区生态环境知识资源中心(Arid): Epidemiological and clinicopathological findings of feline immunodeficiency virus and feline leukemia virus infections in domestic cats from the Brazilian semiarid region

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DOI	10.1016/j.prevetmed.2024.106167
	Epidemiological and clinicopathological findings of feline immunodeficiency virus and feline leukemia virus infections in domestic cats from the Brazilian semiarid region
	Bezerra, Jose Artur Brilhante; Landim, Camila Pontes; Ribeiro, Yara Stephanne Ramos; Tertulino, Moises Dantas; Santos Jr, Ricardo de Freitas; Maranhao, Ana Carolina Pontes de Miranda; Brasil, Arthur Willian de Lima; Antunes, Joao Marcelo Azevedo de Paula; de Azevedo, Sergio Santos
通讯作者	de Azevedo, SS
来源期刊	PREVENTIVE VETERINARY MEDICINE
ISSN	0167-5877
EISSN	1873-1716
出版年	2024
卷号	226
英文摘要	Feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV) are retroviruses of great importance for domestic cats with a worldwide distribution. A retrospective study was conducted to determine the epidemiological and clinicopathological aspects of the infection by FIV and FeLV in cats from the Brazilian semiarid region. Cats treated between 2011 and 2021 at the teaching veterinary hospital of the Federal Rural University of the Semi -Arid Region that were submitted to a point -of -care (POC) test to detect anti-FIV IgG antibodies and FeLV antigen were enrolled in the study. Overall, 454 cats were selected, of which 30.2% [95% CI = 26.0% - 34.3%] were FIV-positive, 1.1% [95% CI = 0.9% - 1.2%] were FeLV-positive, and 0.7% [95% CI = 0.1% - 1.3%] were coinfected by both retroviruses. No statistical association was found between the studied retroviruses (P = 0.144). Multivariable analysis detected significant associations between FIV infection and male sex [OR = 5.7, 95% CI = 3.0-10.7, P < 0.0001), age between 19 and 78 months [OR = 5.2, 95% CI = 2.2-12.1, P < 0.0001], age greater than 78 months [OR = 12.8, 95% CI = 5.1-31.9, P < 0.0001], crossbreed [OR = 4.1, 95% CI = 1.2-13.4, P = 0.021], the presence of oral disease [OR = 2.1, 95% CI = 1.3-3.4, P = 0.004], reduced red blood cell (RBC) count [OR = 3.7, 95% CI = 1.9-7.2, P < 0.0001], and an albumin:globulin (A:G) ratio lower than 0.6 [OR = 3.4, 95% CI = 1.6-7.1, P = 0.001]. No statistical analyses were performed for FeLV infection due to the low number of positive animals. In the quantitative analyses of hematological parameters, FIV-positive cats presented lower values for RBC, hemoglobin, hematocrit, lymphocytes, and platelets compared to the negative animals. In the biochemical profile, cats infected with FIV showed higher creatinine, urea, total protein, and globulin values, while lower values for albumin and A:G ratio were observed (P < 0.05). The findings of this study characterized the prevalence, clinicopathological findings, and risk factors associated with FIV and FeLV in cats from the Brazilian semiarid region. They may help support veterinary practitioners in diagnosing feline retroviruses. The FIV prevalence observed is among the highest reported in Brazil, demonstrating the need for prevention and control strategies for this retrovirus.
英文关键词	Epidemiology Feline retroviruses FIV FeLV Felis catus
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:001206982200001
WOS关键词	TOXOPLASMA-GONDII ; CLINICAL-ASPECTS ; DISEASE ; FELV ; HEMATOLOGY ; STATE ; FIV
WOS类目	Veterinary Sciences
WOS研究方向	Veterinary Sciences
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/405221
推荐引用方式 GB/T 7714	Bezerra, Jose Artur Brilhante,Landim, Camila Pontes,Ribeiro, Yara Stephanne Ramos,et al. Epidemiological and clinicopathological findings of feline immunodeficiency virus and feline leukemia virus infections in domestic cats from the Brazilian semiarid region[J],2024,226.
APA	Bezerra, Jose Artur Brilhante.,Landim, Camila Pontes.,Ribeiro, Yara Stephanne Ramos.,Tertulino, Moises Dantas.,Santos Jr, Ricardo de Freitas.,...&de Azevedo, Sergio Santos.(2024).Epidemiological and clinicopathological findings of feline immunodeficiency virus and feline leukemia virus infections in domestic cats from the Brazilian semiarid region.PREVENTIVE VETERINARY MEDICINE,226.
MLA	Bezerra, Jose Artur Brilhante,et al."Epidemiological and clinicopathological findings of feline immunodeficiency virus and feline leukemia virus infections in domestic cats from the Brazilian semiarid region".PREVENTIVE VETERINARY MEDICINE 226(2024).