干旱区生态环境知识资源中心(Arid): Effects of dietary curcumin nano-micelles on performance, biological responses, and thermal stress resilience in heat-stressed fattening lambs across varying temperature-humidity index conditions: Implications for climate change

Arid

DOI	10.1016/j.jtherbio.2024.103905
	Effects of dietary curcumin nano-micelles on performance, biological responses, and thermal stress resilience in heat-stressed fattening lambs across varying temperature-humidity index conditions: Implications for climate change
	Bokharaeian, Mostafa; Toghdory, Abdolhakim; Ghoorchi, Taghi
通讯作者	Bokharaeian, M
来源期刊	JOURNAL OF THERMAL BIOLOGY
ISSN	0306-4565
EISSN	1879-0992
出版年	2024
卷号	123
英文摘要	Heat stress poses a significant challenge to sheep farming in arid and semi-arid regions, impacting growth performance, health, and physiological responses. While sheep have innate mechanisms to manage heat stress, prolonged exposure impairs their performance and health. This study evaluated the influence of varying doses of Curcumin Nano-Micelle (CNM) on heat-stressed fattening lambs in northeastern Iran over three months, examining the relationship between CNM doses and growth performance, feeding behavior, physiological responses, immune function, and antioxidant status. Thirty-two crossbred male lambs were included in a completely randomized design with four treatments and eight replications. The experimental treatments were as follows: 1) CTRL: No dietary inclusion of CNM, (control group); 2) T20: Dietary inclusion of 20 mg of CNM per head per day; 3) T40: Dietary inclusion of 40 mg of CNM per head per day; and 4) T80: Dietary inclusion of 80 mg of CNM per head per day. The results revealed that dietary supplementation with 20 and 40 mg of CNM significantly improved live body weight, weight gain, average daily gain (ADG), and feed conversion ratio (FCR) compared to the control treatment. Regression analysis demonstrated quadratic models between growth performance parameters and the Temperature-Humidity Index (THI), indicating a correlation between CNM doses and the animals' responses to heat stress. Regarding eating behavior, CNM doses of 40 and 80 mg/day significantly reduced eating time while increasing ruminating time. Blood analysis indicated significant reductions in glucose levels across all treatments, with T40 significantly reducing both cholesterol and triglyceride (TG) levels. Additionally, CNM supplementation decreased serum malondialdehyde (MDA) levels and increased superoxide dismutase (SOD) and glutathione peroxidase (GPx) activities, indicating enhanced antioxidant status. Physiological responses were influenced by CNM, notably reducing rectal temperature (RT), skin temperature (ST), respiration rate (RR), while pulse rate (PR) increased across various time intervals, particularly in the T80 group. This study demonstrates that CNM supplementation can enhance performance, physiological responses, and antioxidant status in heat-stressed fattening lambs, highlighting its potential to mitigate heat stress effects in sheep farming.
英文关键词	Heat stress Sustainable farming Antioxidants Oxidative stress Curcumin nano-micelles
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:001280890400001
WOS关键词	OXIDATIVE STRESS ; IMMUNE FUNCTION ; WEIGHT-GAIN ; DAIRY-COWS ; SHEEP ; ANTIOXIDANT ; GROWTH ; SUPPLEMENTATION ; QUALITY
WOS类目	Biology ; Zoology
WOS研究方向	Life Sciences & Biomedicine - Other Topics ; Zoology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/404743
推荐引用方式 GB/T 7714	Bokharaeian, Mostafa,Toghdory, Abdolhakim,Ghoorchi, Taghi. Effects of dietary curcumin nano-micelles on performance, biological responses, and thermal stress resilience in heat-stressed fattening lambs across varying temperature-humidity index conditions: Implications for climate change[J],2024,123.
APA	Bokharaeian, Mostafa,Toghdory, Abdolhakim,&Ghoorchi, Taghi.(2024).Effects of dietary curcumin nano-micelles on performance, biological responses, and thermal stress resilience in heat-stressed fattening lambs across varying temperature-humidity index conditions: Implications for climate change.JOURNAL OF THERMAL BIOLOGY,123.
MLA	Bokharaeian, Mostafa,et al."Effects of dietary curcumin nano-micelles on performance, biological responses, and thermal stress resilience in heat-stressed fattening lambs across varying temperature-humidity index conditions: Implications for climate change".JOURNAL OF THERMAL BIOLOGY 123(2024).