干旱区生态环境知识资源中心(Arid): Evaluation of the antioxidant and antityrosinase activities of Prosopis juliflora fruit extract as a novel multifunctional bioactive ingredient and its potential applicability in pro-ageing and skin colour harmonization cosmetic products

Arid

DOI	10.1111/ics.13018
	Evaluation of the antioxidant and antityrosinase activities of Prosopis juliflora fruit extract as a novel multifunctional bioactive ingredient and its potential applicability in pro-ageing and skin colour harmonization cosmetic products
	da Silva, Tassyo Leandro; Pinheiro, Jonas Gabriel de Oliveira; de Moura, Arthur Thomaz Coutinho; Maia Neto, Christovam Gondim; Correia, Francisco Lucas Pereira; Comin, Marcielle Sayuri Kubo; da Silva, Rafaela Costa Ferreira; de Araujo, Samara Vitoria Ferreira; Barreto, Stella Maria Andrade Gomes; Oliveira, Artur de Santana; Damasceno, Gabriel Azevedo de Brito; Ferrari, Marcio
通讯作者	Ferrari, M
来源期刊	INTERNATIONAL JOURNAL OF COSMETIC SCIENCE
ISSN	0142-5463
EISSN	1468-2494
出版年	2024
英文摘要	Objective: Prosopis juliflora, commonly known as algaroba or mesquite, was introduced and has since proliferated throughout the semi-arid region of the Caatinga biome. Various studies have documented its properties, including antimicrobial, antioxidant, and antitumor activities, attributed to the presence of diverse secondary metabolites such as alkaloids, terpenoids, tannins, and flavonoids. The objective of this study was to evaluate the antioxidant and antityrosinase activities of P. juliflora fruit extract as a multifunctional active ingredient, and to develop cosmetic formulations containing this vegetal extract for potential applications in skincare products targeting pro-ageing and skin colour homogenization properties. Methods: The extraction process followed established protocols. Chemical characterization of the extract involved quantification of total flavonoids and phenolic compounds, along with Liquid Chromatography-Mass Spectrometry (LC-MS) analysis. In vitro antioxidant activity was assessed using different methods. Antityrosinase activity was determined by employing enzymatic assays. Cosmetic formulations containing Disodium EDTA, Phenoxyethanol (and) Ethylhexyl Glycerin, Distilled Water, Sodium Acrylates Copolymer Lecithin, Polyacrylamide (and) C13-14 Isoparaffin (and) Laureth-7, and 3.0% of the investigated plant extract were subjected to preliminary and accelerated stability tests. Results The extract demonstrated a concentration of total flavonoids (1.71 +/- 0.26 mu g EQ/mg) and exhibited concentrations of phenolic compounds at 0.21 +/- 0.01 mg EAG/g. Metabolites such as flavonoids and saponins were annotated, as well as some of their respective glycosidic derivatives. The extract showed antioxidant potential and the ability to inhibit the oxidation cascade in both the initiation and propagation phases. Moreover, the extract exhibited noteworthy inhibition of antityrosinase activity, presenting 62.48 +/- 2.09 at a concentration of 30.00 mg/mL. The formulations were stable in accelerated stability tests over a 60-day period. Conclusion: This research not only demonstrates scientifically by demonstrating the potential of a plant from the Caatinga biome with antioxidant and antityrosinase properties in the development of cosmetic products aimed at pro-ageing effects and skin colour harmonization, but also adds value to the P. juliflora production chain. This valorization encompasses various aspects which include environmental, social, and biodiversity responsibilities.
英文关键词	Algaroba cosmetic emulsions formulation/stability multifunctional Prosopis juliflora
类型	Article ; Early Access
语种	英语
收录类别	SCI-E
WOS记录号	WOS:001290524900001
WOS关键词	IN-VITRO ; LEAF EXTRACT ; VIVO ; ANTIBACTERIAL ; INHIBITOR ; CAPACITY
WOS类目	Chemistry, Applied ; Dermatology
WOS研究方向	Chemistry ; Dermatology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/404222
推荐引用方式 GB/T 7714	da Silva, Tassyo Leandro,Pinheiro, Jonas Gabriel de Oliveira,de Moura, Arthur Thomaz Coutinho,et al. Evaluation of the antioxidant and antityrosinase activities of Prosopis juliflora fruit extract as a novel multifunctional bioactive ingredient and its potential applicability in pro-ageing and skin colour harmonization cosmetic products[J],2024.
APA	da Silva, Tassyo Leandro.,Pinheiro, Jonas Gabriel de Oliveira.,de Moura, Arthur Thomaz Coutinho.,Maia Neto, Christovam Gondim.,Correia, Francisco Lucas Pereira.,...&Ferrari, Marcio.(2024).Evaluation of the antioxidant and antityrosinase activities of Prosopis juliflora fruit extract as a novel multifunctional bioactive ingredient and its potential applicability in pro-ageing and skin colour harmonization cosmetic products.INTERNATIONAL JOURNAL OF COSMETIC SCIENCE.
MLA	da Silva, Tassyo Leandro,et al."Evaluation of the antioxidant and antityrosinase activities of Prosopis juliflora fruit extract as a novel multifunctional bioactive ingredient and its potential applicability in pro-ageing and skin colour harmonization cosmetic products".INTERNATIONAL JOURNAL OF COSMETIC SCIENCE (2024).