干旱区生态环境知识资源中心(Arid): Does ambient particulate matter 1 increase the risk of gastric cancer in the northwest of China?

Arid

DOI	10.1002/ijc.35144
	Does ambient particulate matter 1 increase the risk of gastric cancer in the northwest of China?
	Liu, Jie; Gan, Ting; Hu, Wenbiao; Li, Yumin
通讯作者	Li, YM
来源期刊	INTERNATIONAL JOURNAL OF CANCER
ISSN	0020-7136
EISSN	1097-0215
出版年	2024
英文摘要	Gastric cancer (GC) remains a significant health concern in Gansu province, China, with morbidity and mortality rates surpassing national averages. Despite the recognized health risks associated with ambient particulate matter with an aerodynamic diameter <1 mu m (PM1), the relationship between PM1 exposure and GC incidence has not been extensively studied. Data on GC cases from 2013 to 2021 were gathered from 262 hospitals in Gansu, China. Concurrently, data on the normalized vegetation index (NDVI), gross domestic product (GDP), drinking and smoking behavioral index (DSBI), PM1, PM2.5, and PM2.5-1 were collected. Utilizing a Bayesian conditional autoregressive (CAR) combined generalized linear model (GLM) with quasi-Poisson regression, we evaluated the impact of PM1, PM2.5, PM2.5-1, NDVI, DSBI, and GDP on GC morbidity while adjusting for potential confounders. Our analysis indicated that exposure to PM1 (mu g/m(3)) is significantly positively correlated with GC incidence in regions with an overall age-standardized incidence rate (ASIR) >40 (relative risks [RR]: 1.023, 95% confidence intervals [CI, 1.007, 1.039]), male ASIR >50 (RR: 1.014, 95% CI [1.009, 1.019]), and female ASIR >20 (RR: 1.010, 95% CI [1.002, 1.018]). PM2.5, PM2.5-1, DSBI, and GDP were positively correlated with GC incidence, while NDVI was negatively correlated in the study regions. Our findings provided evidence of a positive correlation between PM1 exposure and GC incidence in high-risk areas of GC within arid regions. Further research is warranted to elucidate the complex nonlinear relationships between environmental factors and GC. These insights could inform strategies for improving the control and prevention of GC in Gansu and similar regions.
英文关键词	air pollution arid region gastric cancer particulate matter 1 (PM1) particulate matter 2.5 (PM2.5)
类型	Article ; Early Access
语种	英语
收录类别	SCI-E
WOS记录号	WOS:001296773700001
WOS关键词	AIR-POLLUTION ; PM2.5 ; PM1 ; MORTALITY
WOS类目	Oncology
WOS研究方向	Oncology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/404212
推荐引用方式 GB/T 7714	Liu, Jie,Gan, Ting,Hu, Wenbiao,et al. Does ambient particulate matter 1 increase the risk of gastric cancer in the northwest of China?[J],2024.
APA	Liu, Jie,Gan, Ting,Hu, Wenbiao,&Li, Yumin.(2024).Does ambient particulate matter 1 increase the risk of gastric cancer in the northwest of China?.INTERNATIONAL JOURNAL OF CANCER.
MLA	Liu, Jie,et al."Does ambient particulate matter 1 increase the risk of gastric cancer in the northwest of China?".INTERNATIONAL JOURNAL OF CANCER (2024).