Knowledge Resource Center for Ecological Environment in Arid Area
DOI | 10.1109/TNNLS.2022.3220220 |
Contrastive Brain Network Learning via Hierarchical Signed Graph Pooling Model | |
Tang, Haoteng; Ma, Guixiang; Guo, Lei; Fu, Xiyao; Huang, Heng; Zhang, Liang | |
通讯作者 | Zhang, L |
来源期刊 | IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS
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ISSN | 2162-237X |
EISSN | 2162-2388 |
出版年 | 2024 |
卷号 | 35期号:6页码:7363-7375 |
英文摘要 | Recently brain networks have been widely adopted to study brain dynamics, brain development and brain diseases. Graph representation learning techniques on brain functional networks can facilitate the discovery of novel biomarkers for clinical phenotypes and neurodegenerative diseases. However, current graph learning techniques have several issues on brain network mining. Firstly, most current graph learning models are designed for unsigned graph, which hinders the analysis of many signed network data (e.g., brain functional networks). Meanwhile, the insufficiency of brain network data limits the model performance on clinical phenotypes predictions. Moreover, few of current graph learning model is interpretable, which may not be capable to provide biological insights for model outcomes. Here, we propose an interpretable hierarchical signed graph representation learning model to extract graph-level representations from brain functional networks, which can be used for different prediction tasks. In order to further improve the model performance, we also propose a new strategy to augment functional brain network data for contrastive learning. We evaluate this framework on different classification and regression tasks using the data from HCP and OASIS. Our results from extensive experiments demonstrate the superiority of the proposed model compared to several state-of-the-art techniques. Additionally, we use graph saliency maps, derived from these prediction tasks, to demonstrate detection and interpretation of phenotypic biomarkers. |
英文关键词 | Brain functional networks contrastive learning data augmentation hierarchical graph pooling (HGP) interpretability signed graph learning |
类型 | Article |
语种 | 英语 |
开放获取类型 | Green Submitted |
收录类别 | SCI-E |
WOS记录号 | WOS:000886828100001 |
WOS关键词 | MENTAL-STATE-EXAMINATION ; PREDICTION ; ARCHITECTURE ; HUBS |
WOS类目 | Computer Science, Artificial Intelligence ; Computer Science, Hardware & Architecture ; Computer Science, Theory & Methods ; Engineering, Electrical & Electronic |
WOS研究方向 | Computer Science ; Engineering |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/404153 |
推荐引用方式 GB/T 7714 | Tang, Haoteng,Ma, Guixiang,Guo, Lei,et al. Contrastive Brain Network Learning via Hierarchical Signed Graph Pooling Model[J],2024,35(6):7363-7375. |
APA | Tang, Haoteng,Ma, Guixiang,Guo, Lei,Fu, Xiyao,Huang, Heng,&Zhang, Liang.(2024).Contrastive Brain Network Learning via Hierarchical Signed Graph Pooling Model.IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS,35(6),7363-7375. |
MLA | Tang, Haoteng,et al."Contrastive Brain Network Learning via Hierarchical Signed Graph Pooling Model".IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS 35.6(2024):7363-7375. |
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