干旱区生态环境知识资源中心(Arid): Multivariate pattern analysis of medical imaging-based Alzheimer's disease

Arid

DOI	10.3389/fmed.2024.1412592
	Multivariate pattern analysis of medical imaging-based Alzheimer's disease
	Alarjani, Maitha; Almarri, Badar
通讯作者	Almarri, B
来源期刊	FRONTIERS IN MEDICINE
EISSN	2296-858X
出版年	2024
卷号	11
英文摘要	Alzheimer's disease (AD) is a devastating brain disorder that steadily worsens over time. It is marked by a relentless decline in memory and cognitive abilities. As the disease progresses, it leads to a significant loss of mental function. Early detection of AD is essential to starting treatments that can mitigate the progression of this disease and enhance patients' quality of life. This study aims to observe AD's brain functional connectivity pattern to extract essential patterns through multivariate pattern analysis (MVPA) and analyze activity patterns across multiple brain voxels. The optimized feature extraction techniques are used to obtain the important features for performing the training on the models using several hybrid machine learning classifiers for performing binary classification and multi-class classification. The proposed approach using hybrid machine learning classification has been applied to two public datasets named the Open Access Series of Imaging Studies (OASIS) and the AD Neuroimaging Initiative (ADNI). The results are evaluated using performance metrics, and comparisons have been made to differentiate between different stages of AD using visualization tools.
英文关键词	Alzheimer's disease blood flow multivariate pattern analysis fMRI neuroimaging biomarker
类型	Article
语种	英语
开放获取类型	gold, Green Published
收录类别	SCI-E
WOS记录号	WOS:001285358000001
WOS关键词	FUNCTIONAL CONNECTIVITY ; FMRI ; BRAIN ; OXYGENATION ; CONTRAST ; NETWORK ; MRI ; REGISTRATION ; PARCELLATION ; CHALLENGES
WOS类目	Medicine, General & Internal
WOS研究方向	General & Internal Medicine
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/403845
推荐引用方式 GB/T 7714	Alarjani, Maitha,Almarri, Badar. Multivariate pattern analysis of medical imaging-based Alzheimer's disease[J],2024,11.
APA	Alarjani, Maitha,&Almarri, Badar.(2024).Multivariate pattern analysis of medical imaging-based Alzheimer's disease.FRONTIERS IN MEDICINE,11.
MLA	Alarjani, Maitha,et al."Multivariate pattern analysis of medical imaging-based Alzheimer's disease".FRONTIERS IN MEDICINE 11(2024).