干旱区生态环境知识资源中心(Arid): Phytochemical Analysis, Acetylcholinesterase Inhibition, Antidiabetic and Antioxidant Activities of Atriplex halimus L. (Amaranthaceae Juss.)

Arid

DOI	10.1002/cbdv.202301941
	Phytochemical Analysis, Acetylcholinesterase Inhibition, Antidiabetic and Antioxidant Activities of Atriplex halimus L. (Amaranthaceae Juss.)
	Guedri, Mounira Mkaddem; Krir, Nouha; Terol, Carolina Clausell; Romdhane, Mehrez; Boulila, Abdennacer; Guetat, Arbi
通讯作者	Guetat, A
来源期刊	CHEMISTRY & BIODIVERSITY
ISSN	1612-1872
EISSN	1612-1880
出版年	2024
卷号	21 期号:7
英文摘要	Mediterranean saltbush Atriplex halimus L. (Amaranthaceae) from different bioclimatic arid zones (ten wild populations) were studied. Phenols contents, flavonoids, flavonols, tannins and anthocyanins were determined and then tested for their antioxidants, antidiabetic and anti-acetylcholinesterase (AChE) activities. Levels of total polyphenols including flavonoids and flavonols, tannins and anthocyanins were high and varied significantly among analyzed populations. Nine phenolic acids and four flavonoids were identified for the first time in the methanolic fraction and quantified by liquid high-performance chromatography system HPLC (DAD). All extracts showed a substantial antioxidant activity, as assessed by DPPH assay (1,1-diphenyl-2-picrylhydrazyl free radical) (IC50DPPH=147.3for population of Seliena), Ferric Reducing Antioxidant Power (FRAP; IC50FRAP=3.2 for populations of Sousse and Kairouan), and Chelation Fer test (IC50FerCh=1.5 mu g/mL for populations of El-hamma and Mednine). Atriplex halimus possessed a high inhibitory effect against alpha-amylase activity (up to 2.6 mg ACE/gE), a moderate activity for alpha-glucosidase (up to 91.0 mg ACE/gE) and AChE (up to 147.2 mu g/mL) compared to standard. The analyzed populations were isolated and subdivided into three distinct groups, without any bioclimatic structuration. Enzymatic activities seem to be associated with the presence, in plant extracts, of other classes of compounds then phenols such as terpenes, sterols, saponins, coumarins and carotenoids.
英文关键词	Antioxidants activities Atriplex halimus phenolic compounds alpha-amylase inhibition effect alpha-glucosidase inhibition effect
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:001244292300001
WOS关键词	TOTAL PHENOLIC CONTENT ; ALPHA-GLUCOSIDASE ; EXTRACTS ; PLANTS ; ACID ; ANTIBACTERIAL ; REVEGETATION ; FLAVONOIDS ; INFUSIONS ; BIOLOGY
WOS类目	Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/403185
推荐引用方式 GB/T 7714	Guedri, Mounira Mkaddem,Krir, Nouha,Terol, Carolina Clausell,et al. Phytochemical Analysis, Acetylcholinesterase Inhibition, Antidiabetic and Antioxidant Activities of Atriplex halimus L. (Amaranthaceae Juss.)[J],2024,21(7).
APA	Guedri, Mounira Mkaddem,Krir, Nouha,Terol, Carolina Clausell,Romdhane, Mehrez,Boulila, Abdennacer,&Guetat, Arbi.(2024).Phytochemical Analysis, Acetylcholinesterase Inhibition, Antidiabetic and Antioxidant Activities of Atriplex halimus L. (Amaranthaceae Juss.).CHEMISTRY & BIODIVERSITY,21(7).
MLA	Guedri, Mounira Mkaddem,et al."Phytochemical Analysis, Acetylcholinesterase Inhibition, Antidiabetic and Antioxidant Activities of Atriplex halimus L. (Amaranthaceae Juss.)".CHEMISTRY & BIODIVERSITY 21.7(2024).