干旱区生态环境知识资源中心(Arid): Sensitive analysis of 18 aminoglycosides in bovine milk using hydrophilic interaction chromatography combined with tandem mass spectrometry

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DOI	10.1016/j.jfca.2023.105601
	Sensitive analysis of 18 aminoglycosides in bovine milk using hydrophilic interaction chromatography combined with tandem mass spectrometry
	Jia, Xixi; Li, Xiaowei; Zhao, Liang; Liu, Saiwa; Wang, Zhinan; Du, Jingjing; Ge, Lirui; Zhao, Kunxia; Tian, Lu; Xu, Jian; Yan, Zuhao; Ding, Jiangyi; Xia, Xi
通讯作者	Xia, X
来源期刊	JOURNAL OF FOOD COMPOSITION AND ANALYSIS
ISSN	0889-1575
EISSN	1096-0481
出版年	2023
卷号	123
英文摘要	A sensitive and selective method was developed using hydrophilic interaction chromatography combined with tandem mass spectrometry to detect 18 aminoglycosides in bovine milk. Aminoglycosides were extracted from milk using a mixture of trichloroacetic acid, ammonium acetate, ethylenediaminetetraacetic acid, and sodium chloride, and then isolated using an Oasis HLB solid-phase extraction cartridge. We evaluated the performance of chromatographic columns with different stationary phases and optimized the mobile phases to achieve satisfactory separation of the analytes. The limits of detection and quantification were 0.05-2 & mu;g/kg and 0.1-5 & mu;g/kg, respectively. The recoveries of the method ranged from 78.9% to 101.1%, with intra- and inter-day relative standard deviations of less than 8.1% and 9.0%, respectively. This method was applied to 30 milk samples collected from markets, and neomycin (16.8 & mu;g/kg) was detected in one fresh bovine milk sample. The proposed method provides a powerful tool for the surveillance of aminoglycosides in bovine milk.
英文关键词	Aminoglycosides Milk Hydrophilic interaction chromatography Mass spectrometry
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:001060857400001
WOS关键词	SOLID-PHASE EXTRACTION ; PERFORMANCE LIQUID-CHROMATOGRAPHY ; ANIMAL ORIGIN ; RESIDUES ; HONEY ; MICROEXTRACTION ; ANTIBIOTICS ; MUSCLE ; COLUMN ; FOODS
WOS类目	Chemistry, Applied ; Food Science & Technology
WOS研究方向	Chemistry ; Food Science & Technology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/397322
推荐引用方式 GB/T 7714	Jia, Xixi,Li, Xiaowei,Zhao, Liang,et al. Sensitive analysis of 18 aminoglycosides in bovine milk using hydrophilic interaction chromatography combined with tandem mass spectrometry[J],2023,123.
APA	Jia, Xixi.,Li, Xiaowei.,Zhao, Liang.,Liu, Saiwa.,Wang, Zhinan.,...&Xia, Xi.(2023).Sensitive analysis of 18 aminoglycosides in bovine milk using hydrophilic interaction chromatography combined with tandem mass spectrometry.JOURNAL OF FOOD COMPOSITION AND ANALYSIS,123.
MLA	Jia, Xixi,et al."Sensitive analysis of 18 aminoglycosides in bovine milk using hydrophilic interaction chromatography combined with tandem mass spectrometry".JOURNAL OF FOOD COMPOSITION AND ANALYSIS 123(2023).