干旱区生态环境知识资源中心(Arid): Protective role of trehalose in the Namib desert ant, Ocymyrmex robustior

Arid

DOI	10.1242/jeb.245149
	Protective role of trehalose in the Namib desert ant, Ocymyrmex robustior
	Perez, Remy; Aron, Serge
通讯作者	Perez, R
来源期刊	JOURNAL OF EXPERIMENTAL BIOLOGY
ISSN	0022-0949
EISSN	1477-9145
出版年	2023
卷号	226 期号:3
英文摘要	Over recent decades, increasing attention has been paid to how low-molecular-weight molecules affect thermal tolerance in animals. Although the disaccharide sugar trehalose is known to serve as a thermal protectant in unicellular organisms, nothing is known about its potential role in insects. In this study, we investigated the effect of trehalose on heat tolerance in the Namib desert ant, Ocymyrmex robustior, one of the most thermotolerant animals found in terrestrial ecosystems. First, we tested whether a trehalose-supplemented diet increased worker survival following exposure to heat stress. Second, we assessed the degree of protein damage by comparing protein aggregation levels for trehalose-supplemented workers and control workers. Third, we compared the expression levels of three genes involved in trehalose metabolism. We found that trehalose supplementation significantly enhanced worker heat tolerance, increased metabolic levels of trehalose and reduced protein aggregation under conditions of heat stress. Expression levels of the three genes varied in a manner that was consistent with the maintenance of trehalose in the hemolymph and tissues under conditions of heat stress. Altogether, these results suggest that increased trehalose concentration may help protect Namib desert ant individuals against heat stress. More generally, they highlight the role played by sugar metabolites in boosting tolerance in extremophiles.
英文关键词	Sugar Heat tolerance Arid region Hymenoptera RT-qPCR Protein aggregates
类型	Article
语种	英语
开放获取类型	Bronze
收录类别	SCI-E
WOS记录号	WOS:001101784200013
WOS关键词	THERMAL TOLERANCE ; COLD TOLERANCE ; STABILIZATION ; METABOLISM ; DESICCATION ; PROTEINS ; INSECT ; SUGARS ; WATER ; GENE
WOS类目	Biology ; Zoology
WOS研究方向	Life Sciences & Biomedicine - Other Topics ; Zoology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/397315
推荐引用方式 GB/T 7714	Perez, Remy,Aron, Serge. Protective role of trehalose in the Namib desert ant, Ocymyrmex robustior[J],2023,226(3).
APA	Perez, Remy,&Aron, Serge.(2023).Protective role of trehalose in the Namib desert ant, Ocymyrmex robustior.JOURNAL OF EXPERIMENTAL BIOLOGY,226(3).
MLA	Perez, Remy,et al."Protective role of trehalose in the Namib desert ant, Ocymyrmex robustior".JOURNAL OF EXPERIMENTAL BIOLOGY 226.3(2023).