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DOI | 10.1016/j.heliyon.2023.e16295 |
Urine output for predicting in-hospital mortality of intensive care patients with cardiogenic shock | |
Hu, Tianyang; Huang, Rongzhong | |
通讯作者 | Huang, RZ |
来源期刊 | HELIYON
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EISSN | 2405-8440 |
出版年 | 2023 |
卷号 | 9期号:6 |
英文摘要 | Background: The role of urine output (UO) in the first 24 h of admission in the clinical management of cardiogenic shock (CS) patients has not been elucidated. Methods: This study retrospectively analyzed intensive care CS patients in the MIMIC-IV database. Binomial logistic regression analysis was conducted to evaluate whether UO was an independent risk factor for in-hospital mortality in CS patients. The performance of UO in predicting mortality was evaluated by the receiver operating characteristic (ROC) curve and compared with the Oxford Acute Severity of Illness Score (OASIS). The clinical net benefit of UO in predicting mortality was determined using the decision curve analysis (DCA). Survival analysis was performed with Kaplan-Meier curves. Results: After adjusting for confounding factors including diuretic use and acute kidney injury (AKI), UO remained an independent risk factor for in-hospital mortality in CS patients. The areas under the ROC curves (AUCs) of UO for predicting in-hospital mortality were 0.712 (UO, ml/day) and 0.701 (UO, ml/kg/h), which were comparable to OASIS (AUC = 0.695). In terms of clinical net benefit, UO was comparable to OASIS, with different degrees of benefit at different threshold probabilities. Survival analysis showed that the risk of in-hospital death in the low-UO (& LE;857 ml/ day) group was 3.0143 times that of the high-UO (>857 ml/day) group. Conclusions: UO in the first 24 h of admission is an independent risk factor for in-hospital mortality in intensive care CS patients and has moderate predictive value in predicting in-hospital mortality. |
英文关键词 | Cardiogenic shock Urine output Oxford acute severity of illness score MIMIC -IV In -hospital mortality |
类型 | Article |
语种 | 英语 |
开放获取类型 | gold, Green Published |
收录类别 | SCI-E |
WOS记录号 | WOS:001022026300001 |
WOS关键词 | ACUTE KIDNEY INJURY ; ACUTE PHYSIOLOGY ; SEVERITY ; OLIGURIA ; OVERLOAD ; SUPPORT ; SCORE |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/396815 |
推荐引用方式 GB/T 7714 | Hu, Tianyang,Huang, Rongzhong. Urine output for predicting in-hospital mortality of intensive care patients with cardiogenic shock[J],2023,9(6). |
APA | Hu, Tianyang,&Huang, Rongzhong.(2023).Urine output for predicting in-hospital mortality of intensive care patients with cardiogenic shock.HELIYON,9(6). |
MLA | Hu, Tianyang,et al."Urine output for predicting in-hospital mortality of intensive care patients with cardiogenic shock".HELIYON 9.6(2023). |
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