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DOI10.1016/j.heliyon.2023.e16295
Urine output for predicting in-hospital mortality of intensive care patients with cardiogenic shock
Hu, Tianyang; Huang, Rongzhong
通讯作者Huang, RZ
来源期刊HELIYON
EISSN2405-8440
出版年2023
卷号9期号:6
英文摘要Background: The role of urine output (UO) in the first 24 h of admission in the clinical management of cardiogenic shock (CS) patients has not been elucidated. Methods: This study retrospectively analyzed intensive care CS patients in the MIMIC-IV database. Binomial logistic regression analysis was conducted to evaluate whether UO was an independent risk factor for in-hospital mortality in CS patients. The performance of UO in predicting mortality was evaluated by the receiver operating characteristic (ROC) curve and compared with the Oxford Acute Severity of Illness Score (OASIS). The clinical net benefit of UO in predicting mortality was determined using the decision curve analysis (DCA). Survival analysis was performed with Kaplan-Meier curves. Results: After adjusting for confounding factors including diuretic use and acute kidney injury (AKI), UO remained an independent risk factor for in-hospital mortality in CS patients. The areas under the ROC curves (AUCs) of UO for predicting in-hospital mortality were 0.712 (UO, ml/day) and 0.701 (UO, ml/kg/h), which were comparable to OASIS (AUC = 0.695). In terms of clinical net benefit, UO was comparable to OASIS, with different degrees of benefit at different threshold probabilities. Survival analysis showed that the risk of in-hospital death in the low-UO (& LE;857 ml/ day) group was 3.0143 times that of the high-UO (>857 ml/day) group. Conclusions: UO in the first 24 h of admission is an independent risk factor for in-hospital mortality in intensive care CS patients and has moderate predictive value in predicting in-hospital mortality.
英文关键词Cardiogenic shock Urine output Oxford acute severity of illness score MIMIC -IV In -hospital mortality
类型Article
语种英语
开放获取类型gold, Green Published
收录类别SCI-E
WOS记录号WOS:001022026300001
WOS关键词ACUTE KIDNEY INJURY ; ACUTE PHYSIOLOGY ; SEVERITY ; OLIGURIA ; OVERLOAD ; SUPPORT ; SCORE
WOS类目Multidisciplinary Sciences
WOS研究方向Science & Technology - Other Topics
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/396815
推荐引用方式
GB/T 7714
Hu, Tianyang,Huang, Rongzhong. Urine output for predicting in-hospital mortality of intensive care patients with cardiogenic shock[J],2023,9(6).
APA Hu, Tianyang,&Huang, Rongzhong.(2023).Urine output for predicting in-hospital mortality of intensive care patients with cardiogenic shock.HELIYON,9(6).
MLA Hu, Tianyang,et al."Urine output for predicting in-hospital mortality of intensive care patients with cardiogenic shock".HELIYON 9.6(2023).
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