干旱区生态环境知识资源中心(Arid): Global Marine Cold Seep Metagenomes Reveal Diversity of Taxonomy, Metabolic Function, and Natural Products

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DOI	10.1093/gpbjnl/qzad006
	Global Marine Cold Seep Metagenomes Reveal Diversity of Taxonomy, Metabolic Function, and Natural Products
	Yu, Tao; Luo, Yingfeng; Tan, Xinyu; Zhao, Dahe; Bi, Xiaochun; Li, Chenji; Zheng, Yanning; Xiang, Hua; Hu, Songnian
通讯作者	Xiang, H ; Hu, SN
来源期刊	GENOMICS PROTEOMICS & BIOINFORMATICS
ISSN	1672-0229
EISSN	2210-3244
出版年	2023
卷号	22 期号:2
英文摘要	Cold seeps in the deep sea are closely linked to energy exploration as well as global climate change. The alkane-dominated chemical energy-driven model makes cold seeps an oasis of deep-sea life, showcasing an unparalleled reservoir of microbial genetic diversity. Here, by analyzing 113 metagenomes collected from 14 global sites across 5 cold seep types, we present a comprehensive Cold Seep Microbiomic Database (CSMD) to archive the genomic and functional diversity of cold seep microbiomes. The CSMD includes over 49 million non-redundant genes and 3175 metagenome-assembled genomes, which represent 1895 species spanning 105 phyla. In addition, beta diversity analysis indicates that both the sampling site and cold seep type have a substantial impact on the prokaryotic microbiome community composition. Heterotrophic and anaerobic metabolisms are prevalent in microbial communities, accompanied by considerable mixotrophs and facultative anaerobes, highlighting the versatile metabolic potential in cold seeps. Furthermore, secondary metabolic gene cluster analysis indicates that at least 98.81% of the sequences potentially encode novel natural products, with ribosomally synthesized and post-translationally modified peptides being the predominant type widely distributed in archaea and bacteria. Overall, the CSMD represents a valuable resource that would enhance the understanding and utilization of global cold seep microbiomes.
英文关键词	Global marine cold seep Metagenome Prokaryotic microbiome Metabolic function Natural product
类型	Article
语种	英语
开放获取类型	gold, Green Submitted
收录类别	SCI-E
WOS记录号	WOS:001293192200001
WOS关键词	ALIGNMENT ; ALGORITHM ; GENOMES ; GENES ; TOOL
WOS类目	Genetics & Heredity
WOS研究方向	Genetics & Heredity
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/396670
推荐引用方式 GB/T 7714	Yu, Tao,Luo, Yingfeng,Tan, Xinyu,et al. Global Marine Cold Seep Metagenomes Reveal Diversity of Taxonomy, Metabolic Function, and Natural Products[J],2023,22(2).
APA	Yu, Tao.,Luo, Yingfeng.,Tan, Xinyu.,Zhao, Dahe.,Bi, Xiaochun.,...&Hu, Songnian.(2023).Global Marine Cold Seep Metagenomes Reveal Diversity of Taxonomy, Metabolic Function, and Natural Products.GENOMICS PROTEOMICS & BIOINFORMATICS,22(2).
MLA	Yu, Tao,et al."Global Marine Cold Seep Metagenomes Reveal Diversity of Taxonomy, Metabolic Function, and Natural Products".GENOMICS PROTEOMICS & BIOINFORMATICS 22.2(2023).