干旱区生态环境知识资源中心(Arid): Tissue-resident memory T cells in gastrointestinal tumors: turning immune desert into immune oasis

Arid

DOI	10.3389/fimmu.2023.1119383
	Tissue-resident memory T cells in gastrointestinal tumors: turning immune desert into immune oasis
	Liang, Mengjie; Wang, Xingzhou; Cai, Daming; Guan, Wenxian; Shen, Xiaofei
通讯作者	Guan, WX ; Shen, XF
来源期刊	FRONTIERS IN IMMUNOLOGY
ISSN	1664-3224
出版年	2023
卷号	14
英文摘要	Tissue-resident memory T cells (Trm) are a particular type of T cell subgroup, which stably reside in tissues and have been revealed to be the most abundant memory T cell population in various tissues. They can be activated in the local microenvironment by infection or tumor cells and rapidly clean them up to restore homeostasis of local immunity in gastrointestinal tissues. Emerging evidence has shown that tissue-resident memory T cells have great potential to be mucosal guardians against gastrointestinal tumors. Therefore, they are considered potential immune markers for immunotherapy of gastrointestinal tumors and potential extraction objects for cell therapy with essential prospects in clinical translational therapy. This paper systematically reviews the role of tissue-resident memory T cells in gastrointestinal tumors and looks to the future of their prospect in immunotherapy to provide a reference for clinical application.
英文关键词	tissue resident memory T gastrointestinal tumor anti-tumor response cancer immunotherapy tumor immune microenvironment
类型	Review
语种	英语
开放获取类型	Green Published, gold
收录类别	SCI-E
WOS记录号	WOS:000954699700001
WOS关键词	MOLECULAR SIGNATURE ; NONLYMPHOID TISSUES ; COLORECTAL-CANCER ; GASTRIC-CANCER ; RESPONSES ; EXHAUSTION ; SURVIVAL ; CD103 ; DIFFERENTIATION ; LYMPHOCYTES
WOS类目	Immunology
WOS研究方向	Immunology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/396544
推荐引用方式 GB/T 7714	Liang, Mengjie,Wang, Xingzhou,Cai, Daming,et al. Tissue-resident memory T cells in gastrointestinal tumors: turning immune desert into immune oasis[J],2023,14.
APA	Liang, Mengjie,Wang, Xingzhou,Cai, Daming,Guan, Wenxian,&Shen, Xiaofei.(2023).Tissue-resident memory T cells in gastrointestinal tumors: turning immune desert into immune oasis.FRONTIERS IN IMMUNOLOGY,14.
MLA	Liang, Mengjie,et al."Tissue-resident memory T cells in gastrointestinal tumors: turning immune desert into immune oasis".FRONTIERS IN IMMUNOLOGY 14(2023).