Arid
DOI10.1038/s41433-023-02472-5
The role of a multicentre data repository in ocular inflammation: The Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS)
Ng, Sean Ming Sheng; Low, Rebecca; Pak, Clara; Lai, SerSei; Lee, Bernett; McCluskey, Peter; Symes, Richard; Invernizzi, Alessandro; Tsui, Edmund; Sitaula, Ranju Kharel; Kharel, Muna; Khatri, Anadi; Utami, Anna Nur; La Distia Nora, Rina; Putera, Ikhwanuliman; Sen, Alok; Agarwal, Manisha; Mahendradas, Padmamalini H.; Biswas, Jyotirmay; Pavesio, Carlos; Cimino, Luca; Sobrin, Lucia; Kempen, John; Gupta, Vishali; Agrawal, Rupesh
通讯作者Agrawal, R
来源期刊EYE
ISSN0950-222X
EISSN1476-5454
出版年2023
卷号37期号:15页码:3084-3096
英文摘要In the current literature, clinical registry cohorts related to ocular inflammation are few and far between, and there are none involving multi-continental international data. Many existing registries comprise administrative databases, data related to specific uveitic diseases, or are designed to address a particular clinical problem. The existing data, although useful and serving their intended purposes, are segmented and may not be sufficiently robust to design prognostication tools or draw epidemiological conclusions in the field of uveitis and ocular inflammation. To solve this, we have developed the Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) Clinical Registry. OASIS collects prospective and retrospective data on patients with all types of ocular inflammatory conditions from centers all around the world. It is a primarily web-based platform with alternative offline modes of access. A comprehensive set of clinical data ranging from demographics, past medical history, clinical presentation, working diagnosis to visual outcomes are collected over a range of time points. Additionally, clinical images such as optical coherence tomography, fundus fluorescein angiography and indocyanine green angiography studies may be uploaded. Through the capturing of diverse, well-structured, and clinically meaningful data in a simplified and consistent fashion, OASIS will deliver a comprehensive and well organized data set ripe for data analysis. The applications of the registry are numerous, and include performing epidemiological analysis, monitoring drug side effects, and studying treatment safety efficacy. Furthermore, the data compiled in OASIS will be used to develop new classification and diagnostic systems, as well as treatment and prognostication guidelines for uveitis.
类型Review
语种英语
收录类别SCI-E
WOS记录号WOS:000949784600002
WOS关键词EYE DISEASES ; UVEITIS ; ADALIMUMAB ; METHOTREXATE ; THERAPY
WOS类目Ophthalmology
WOS研究方向Ophthalmology
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/396347
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Ng, Sean Ming Sheng,Low, Rebecca,Pak, Clara,et al. The role of a multicentre data repository in ocular inflammation: The Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS)[J],2023,37(15):3084-3096.
APA Ng, Sean Ming Sheng.,Low, Rebecca.,Pak, Clara.,Lai, SerSei.,Lee, Bernett.,...&Agrawal, Rupesh.(2023).The role of a multicentre data repository in ocular inflammation: The Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS).EYE,37(15),3084-3096.
MLA Ng, Sean Ming Sheng,et al."The role of a multicentre data repository in ocular inflammation: The Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS)".EYE 37.15(2023):3084-3096.
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