干旱区生态环境知识资源中心(Arid): Trace determination of fifteen free amino acids in drinking source water via solid-phase extraction coupled with liquid chromatography tandem mass spectrometry

Arid

DOI	10.1007/s11356-022-22133-6
	Trace determination of fifteen free amino acids in drinking source water via solid-phase extraction coupled with liquid chromatography tandem mass spectrometry
	Li, Ying-qiang; Liu, Ze-hua; Chen, Sa; Wu, Ying-juan; Liang, Jing-tang; Dang, Zhi; Liu, Yun
通讯作者	Liu, ZH
来源期刊	ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
ISSN	0944-1344
EISSN	1614-7499
出版年	2023
卷号	30 期号:1 页码:594-605
英文摘要	Amino acids (AAs) are important nitrogen-containing organics in water, and a large number of reports have proven that they were the precursors of many nitrogen-containing disinfection by-products, some of which have cytotoxicity and carcinogenicity. However, little has been done on their occurrence in drinking source water. Therefore, a trace determination method via solid-phase extraction coupled with ultra-high pressure liquid chromatography tandem mass spectrometry (UPLC-MS/MS) for 15 free AAs (FAAs) was developed, which was successfully applied for drinking source water samples. For sample preparation, strong cation-exchange stationary solid-phase extraction (SPE) cartridge showed better extraction performance to that of reverse phase stationary oasis HLB SPE cartridge. The optimal water pH was determined to be 2.8 before extraction. Strong matrix effects for most FAAs were observed in this work; thus, sample extraction with SPE was recommended to eliminate the matrix effects. The developed method showed excellent linearity (R-2 > 0.991), low limits of detection (LODs, 0.01-0.27 nmol/L), and good recoveries of 69.8-117.9% in drinking source water with low relative standard deviations (RSDs, 0.3-13.2%). The developed method was finally applied to eight drinking source water samples, and the top five FAAs were found to be serine, glycine, leucine, alanine, and isoleucine.
英文关键词	Free amino acids Solid-phase extraction UPLC-MS/MS Drinking source water Trace determination
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000834592200001
WOS关键词	WASTE-WATER ; ORGANIC-MATTER ; MODEL SOLUTIONS ; LC-MS/MS ; CHLORINATION ; NITROGEN ; DERIVATIZATION ; CHLORAMINES ; ESTROGENS ; CARBON
WOS类目	Environmental Sciences
WOS研究方向	Environmental Sciences & Ecology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/396234
推荐引用方式 GB/T 7714	Li, Ying-qiang,Liu, Ze-hua,Chen, Sa,et al. Trace determination of fifteen free amino acids in drinking source water via solid-phase extraction coupled with liquid chromatography tandem mass spectrometry[J],2023,30(1):594-605.
APA	Li, Ying-qiang.,Liu, Ze-hua.,Chen, Sa.,Wu, Ying-juan.,Liang, Jing-tang.,...&Liu, Yun.(2023).Trace determination of fifteen free amino acids in drinking source water via solid-phase extraction coupled with liquid chromatography tandem mass spectrometry.ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,30(1),594-605.
MLA	Li, Ying-qiang,et al."Trace determination of fifteen free amino acids in drinking source water via solid-phase extraction coupled with liquid chromatography tandem mass spectrometry".ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH 30.1(2023):594-605.