干旱区生态环境知识资源中心(Arid): Individual variation within wild populations of an arid-zone lizard dictates oxidative stress levels despite exposure to sublethal pesticides

Arid

DOI	10.1007/s10646-023-02653-8
	Individual variation within wild populations of an arid-zone lizard dictates oxidative stress levels despite exposure to sublethal pesticides
	Contador-Kelsall, Isabella; Maute, Kimberly; de Beer, Maxwell; French, Kristine
通讯作者	Contador-Kelsall, I
来源期刊	ECOTOXICOLOGY
ISSN	0963-9292
EISSN	1573-3017
出版年	2023
卷号	32 期号:4 页码:470-486
英文摘要	The relationship between sublethal pesticide exposure and oxidative stress in an ecologically relevant field setting is relatively unknown for reptiles. Oxidative stress is a multi-faceted concept that dictates key survival and fitness parameters in any organism. Fipronil and fenitrothion are two pesticides widely used globally for agricultural pest management. Using a field-based, BACI designed experiment we investigated the impact of sublethal pesticide exposure on oxidative stress biomarkers protein carbonyl and DNA damage (8-OHdG), in an arid-zone lizard species, Pogona vitticeps. A single ecologically relevant dose of pesticide was applied via oral gavage to treatment animals. Lizard condition, activity measures, and blood biomarkers were measured at relevant sampling intervals. Cholinesterase (ChE) and acetylcholinesterase (AChE) enzymatic biomarkers were measured in response to fenitrothion, and fipronil blood residues were measured for fipronil-treated lizards. Results suggested no significant treatment effect of either pesticide on parameters measured, however, 8-OHdG levels decreased by >= 45% for both pesticide treatment groups and not controls. Protein carbonyl levels showed a high degree of individual variation that proved more influential than pesticide exposure. Building our understanding of the macromolecular impacts of sublethal pesticide exposure on wild lizard populations is an integral step in addressing the current gap in literature and management practices. Our study has also highlighted the complex nature of studying oxidative stress in the field and the sheer necessity of future study.
英文关键词	Arid-zone DNA damage Lizard Oxidative stress Pesticide Protein carbonyl
类型	Article
语种	英语
开放获取类型	Green Published, hybrid
收录类别	SCI-E
WOS记录号	WOS:000983703700001
WOS关键词	PROTEIN OXIDATION ; HOUSE SPARROW ; FREE-RADICALS ; TOXICITY ; INSECTICIDE ; FIPRONIL ; REPTILES ; DAMAGE ; ORGANOPHOSPHORUS ; ECOTOXICOLOGY
WOS类目	Ecology ; Environmental Sciences ; Toxicology
WOS研究方向	Environmental Sciences & Ecology ; Toxicology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/396038
推荐引用方式 GB/T 7714	Contador-Kelsall, Isabella,Maute, Kimberly,de Beer, Maxwell,et al. Individual variation within wild populations of an arid-zone lizard dictates oxidative stress levels despite exposure to sublethal pesticides[J],2023,32(4):470-486.
APA	Contador-Kelsall, Isabella,Maute, Kimberly,de Beer, Maxwell,&French, Kristine.(2023).Individual variation within wild populations of an arid-zone lizard dictates oxidative stress levels despite exposure to sublethal pesticides.ECOTOXICOLOGY,32(4),470-486.
MLA	Contador-Kelsall, Isabella,et al."Individual variation within wild populations of an arid-zone lizard dictates oxidative stress levels despite exposure to sublethal pesticides".ECOTOXICOLOGY 32.4(2023):470-486.