干旱区生态环境知识资源中心(Arid): The Optimizing Lung Screening Trial (WF-20817CD) Multicenter Randomized Effectiveness Implementation Trial to Increase Tobacco Use Cessation for Individuals Undergoing Lung Screening

Arid

DOI	10.1016/j.chest.2023.03.013
	The Optimizing Lung Screening Trial (WF-20817CD) Multicenter Randomized Effectiveness Implementation Trial to Increase Tobacco Use Cessation for Individuals Undergoing Lung Screening
	Foley, Kristie L.; Dressler, Emily V.; Weaver, Kathryn E.; Sutfin, Erin L.; Miller Jr, David P.; Bellinger, Christina; Kittel, Carol; Stone, Rebecca J.; Petty, W. Jeffrey; Land, Stephanie R.; Spangler, John G.; Lesser, Glenn J.; Chiles, Caroline
通讯作者	Foley, KL
来源期刊	CHEST
ISSN	0012-3692
EISSN	1931-3543
出版年	2023
卷号	164 期号:2 页码:531-543
英文摘要	BACKGROUND: One-half of all people who undergo lung cancer screening (LCS) currently use tobacco. However, few published studies have explored how to implement effective tobacco use treatment optimally during the LCS encounter.RESEARCH QUESTION: Was the Optimizing Lung Screening intervention (OaSiS) effective at reducing tobacco use among patients undergoing LCS in community-based radiology facilities?STUDY DESIGN AND METHODS: The OaSiS study (National Cancer Institute [NCI] Protocol No.: WF-20817CD) is an effectiveness-implementation hybrid type II cluster randomized trial of radiology facilities conducted in partnership with the Wake Forest National Cancer Institute Community Oncology Research Program research base. We randomly assigned 26 radiology facilities in 20 states to the intervention or usual care group. Staff at intervention facilities implemented a variety of strategies targeting the clinic and care team. Eligible patient participants were aged 55 to 77 years undergoing LCS and currently using tobacco. Of 1,094 who completed a baseline survey (523 intervention group, 471 control group) immediately before the LCS appointment, 956 completed the 6-month follow-up (86% retention rate). Fifty-four percent of those who reported not using tobacco at 6 months completed biochemical verification via mailed cotinine assay. Generalized estimating equation marginal models were used in an intention-to-treat analysis to predict 7-day tobacco use abstinence.RESULTS: The average self-reported abstinence among participants varied considerably across facilities (0%-27%). Despite a significant increase in average cessation rate over time (0% at baseline to approximately 13% at 6 months; P < .0001), tobacco use did not differ by trial group at 14 days (OR, 0.96; 95% CI, 0.46-1.99; P = .90), 3 months (OR, 1.17; 95% CI, 0.691.99; P = .56), or 6 months (OR, 0.97; 95% CI, 0.65-1.43; P = .87).INTERPRETATION: The OaSiS trial participants showed a significant reduction in tobacco use over time, but no difference by trial arm was found.
英文关键词	cessation implementation lung cancer screening NCORP smoking
类型	Article
语种	英语
开放获取类型	hybrid, Green Published
收录类别	SCI-E
WOS记录号	WOS:001109077500001
WOS关键词	SMOKING-CESSATION ; DEPENDENCE ; READINESS ; MORTALITY
WOS类目	Critical Care Medicine ; Respiratory System
WOS研究方向	General & Internal Medicine ; Respiratory System
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/395745
推荐引用方式 GB/T 7714	Foley, Kristie L.,Dressler, Emily V.,Weaver, Kathryn E.,et al. The Optimizing Lung Screening Trial (WF-20817CD) Multicenter Randomized Effectiveness Implementation Trial to Increase Tobacco Use Cessation for Individuals Undergoing Lung Screening[J],2023,164(2):531-543.
APA	Foley, Kristie L..,Dressler, Emily V..,Weaver, Kathryn E..,Sutfin, Erin L..,Miller Jr, David P..,...&Chiles, Caroline.(2023).The Optimizing Lung Screening Trial (WF-20817CD) Multicenter Randomized Effectiveness Implementation Trial to Increase Tobacco Use Cessation for Individuals Undergoing Lung Screening.CHEST,164(2),531-543.
MLA	Foley, Kristie L.,et al."The Optimizing Lung Screening Trial (WF-20817CD) Multicenter Randomized Effectiveness Implementation Trial to Increase Tobacco Use Cessation for Individuals Undergoing Lung Screening".CHEST 164.2(2023):531-543.