Arid
DOI10.1186/s12911-023-02293-2
A comparison of random survival forest and Cox regression for prediction of mortality in patients with hemorrhagic stroke
Wang, Yuxin; Deng, Yuhan; Tan, Yinliang; Zhou, Meihong; Jiang, Yong; Liu, Baohua
通讯作者Liu, BH
来源期刊BMC MEDICAL INFORMATICS AND DECISION MAKING
EISSN1472-6947
出版年2023
卷号23期号:1
英文摘要Objective To evaluate RSF and Cox models for mortality prediction of hemorrhagic stroke (HS) patients in intensive care unit (ICU).Methods In the training set, the optimal models were selected using five-fold cross-validation and grid search method. In the test set, the bootstrap method was used to validate. The area under the curve(AUC) was used for discrimination, Brier Score (BS) was used for calibration, positive predictive value(PPV), negative predictive value(NPV), and F1 score were combined to compare.Results A total of 2,990 HS patients were included. For predicting the 7-day mortality, the mean AUCs for RSF and Cox regression were 0.875 and 0.761, while the mean BS were 0.083 and 0.108. For predicting the 28-day mortality, the mean AUCs for RSF and Cox regression were 0.794 and 0.649, while the mean BS were 0.129 and 0.174. The mean AUCs of RSF and Cox versus conventional scores for predicting patients' 7-day mortality were 0.875 (RSF), 0.761 (COX), 0.736 (SAPS II), 0.723 (OASIS), 0.632 (SIRS), and 0.596 (SOFA), respectively.Conclusions RSF provided a better clinical reference than Cox. Creatine, temperature, anion gap and sodium were important variables in both models.
英文关键词Hemorrhagic stroke Random survival forest Cox regression Intensive care unit
类型Article
语种英语
开放获取类型gold, Green Published
收录类别SCI-E
WOS记录号WOS:001099637300002
WOS关键词ACUTE PHYSIOLOGY ; ANION GAP ; MODEL ; SCORE ; SEVERITY
WOS类目Medical Informatics
WOS研究方向Medical Informatics
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/395584
推荐引用方式
GB/T 7714
Wang, Yuxin,Deng, Yuhan,Tan, Yinliang,et al. A comparison of random survival forest and Cox regression for prediction of mortality in patients with hemorrhagic stroke[J],2023,23(1).
APA Wang, Yuxin,Deng, Yuhan,Tan, Yinliang,Zhou, Meihong,Jiang, Yong,&Liu, Baohua.(2023).A comparison of random survival forest and Cox regression for prediction of mortality in patients with hemorrhagic stroke.BMC MEDICAL INFORMATICS AND DECISION MAKING,23(1).
MLA Wang, Yuxin,et al."A comparison of random survival forest and Cox regression for prediction of mortality in patients with hemorrhagic stroke".BMC MEDICAL INFORMATICS AND DECISION MAKING 23.1(2023).
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