干旱区生态环境知识资源中心(Arid): ANTIMITOTIC AND GENOTOXIC EFFECT OF METHANOLIC EXTRACTS OF LEAVES OF Peganum harmala L. ON THE MERISTEMATIC CELLS OF Allium cepa L.

Arid

DOI	10.51372/bioagro352.2
	ANTIMITOTIC AND GENOTOXIC EFFECT OF METHANOLIC EXTRACTS OF LEAVES OF Peganum harmala L. ON THE MERISTEMATIC CELLS OF Allium cepa L.
	Ouzid, Yasmina; Kaci-Boudiaf, Malika Nait; Zeghouini, Assia; Madi, Aghiles-Ouali; Smail-Saadoun, Noria; Houali, Karim
通讯作者	Ouzid, Y
来源期刊	BIOAGRO
ISSN	1316-3361
EISSN	2521-9693
出版年	2023
卷号	35 期号:2 页码:97-104
英文摘要	Medicinal plants are an inexhaustible source of molecules with several biological activities. The main objective of this research was the evaluation of the antimitotic and genotoxic effect by the Allium cepa test of the methanolic extract of the leaves of Peganum harmala, a spontaneous plant from the arid zones of Algeria (Timzerth, Laghouat). Different concentrations (1, 4, 10, and 16 mg center dot mL-1) of the extract, as well as two standards (colchicine and quercetin) at 1 mg center dot mL-1 concentration were tested. Mitotic index (MI), limit value for cytotoxicity (LVC), phase index (PI), and aberration indexes (AI) were calculated, and different aberrations were identified in treated meristematic onion cells. Statistical analyses by ANOVA and Newman-Keuls test were performed. The results confirmed our previous findings that the methanolic extract has an anti-mitotic effect similar to that of the standards. The increase in extract concentrations was accompanied by a decrease in the various indexes calculated. The extracts blocked mitosis in prophase which was predominantly present, and caused increase in abnormalities, represented by dominant rates of agglutinations, chromosomal fragmentations and binuclear cells. confirmed that the effect was independent of concentrations, though to varying degrees.
英文关键词	Arid zones colchicine medicinal plants mitotic index quercetin
类型	Article
语种	英语
开放获取类型	Green Submitted, gold
收录类别	SCI-E
WOS记录号	WOS:001011298200002
WOS类目	Agriculture, Multidisciplinary ; Agronomy
WOS研究方向	Agriculture
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/395535
推荐引用方式 GB/T 7714	Ouzid, Yasmina,Kaci-Boudiaf, Malika Nait,Zeghouini, Assia,et al. ANTIMITOTIC AND GENOTOXIC EFFECT OF METHANOLIC EXTRACTS OF LEAVES OF Peganum harmala L. ON THE MERISTEMATIC CELLS OF Allium cepa L.[J],2023,35(2):97-104.
APA	Ouzid, Yasmina,Kaci-Boudiaf, Malika Nait,Zeghouini, Assia,Madi, Aghiles-Ouali,Smail-Saadoun, Noria,&Houali, Karim.(2023).ANTIMITOTIC AND GENOTOXIC EFFECT OF METHANOLIC EXTRACTS OF LEAVES OF Peganum harmala L. ON THE MERISTEMATIC CELLS OF Allium cepa L..BIOAGRO,35(2),97-104.
MLA	Ouzid, Yasmina,et al."ANTIMITOTIC AND GENOTOXIC EFFECT OF METHANOLIC EXTRACTS OF LEAVES OF Peganum harmala L. ON THE MERISTEMATIC CELLS OF Allium cepa L.".BIOAGRO 35.2(2023):97-104.