干旱区生态环境知识资源中心(Arid): Structural Characterization of Polysaccharides from Coriandrum sativum Seeds: Hepatoprotective Effect against Cadmium Toxicity In Vivo

Arid

DOI	10.3390/antiox12020455
	Structural Characterization of Polysaccharides from Coriandrum sativum Seeds: Hepatoprotective Effect against Cadmium Toxicity In Vivo
	Sfar, Manel; Souid, Ghada; Alminderej, Fahad M. M.; Mzoughi, Zeineb; El-Ghoul, Yassine; Rihouey, Christophe; Le Cerf, Didier; Majdoub, Hatem
通讯作者	Alminderej, FM ; El-Ghoul, Y
来源期刊	ANTIOXIDANTS
EISSN	2076-3921
出版年	2023
卷号	12 期号:2
英文摘要	Coriandrum sativum is one of the most widespread curative plants in the world, being vastly cultivated in arid and semi-arid regions as one of the oldest spice plants. The present study explored the extraction of polysaccharides from Coriandrum sativum seeds and the evaluation of their antioxidant potential and hepatoprotective effects in vivo. The polysaccharide from coriander seeds was extracted, and the structural characterization was performed by FT-IR, UV-vis, DSC, NMR (1D and 2D), GC-MS, and SEC analysis. The polysaccharide extracted from Coriandrum sativum (CPS) seeds was characterized to evaluate its antioxidant and hepatoprotective capacities in rats. Results showed that CPS was composed of arabinose, rhamnose, xylose, mannose, fructose, galactose, and glucose in molar percentages of 6.2%, 3.6%, 8.8%, 17.7%, 5.2%, 32.9%, and 25.6%, respectively. Further, CPS significantly hindered cadmium-induced oxidation damage and exercised a protective effect against Cd hepatocytotoxicity, with a considerable reduction in MDA production and interesting CAT and SOD enzyme levels. Results suggest that CPS might be employed as a natural antioxidant source.
英文关键词	Coriandrum sativum polysaccharide physicochemical characterizations antioxidants hepatocytotoxicity
类型	Article
语种	英语
开放获取类型	Green Published, gold
收录类别	SCI-E
WOS记录号	WOS:000937888100001
WOS关键词	PHYSICOCHEMICAL CHARACTERIZATION ; PECTIC POLYSACCHARIDES ; RHAMNOGALACTURONAN-I ; ANTIOXIDANT ACTIVITY ; EXTRACTION ; L.
WOS类目	Biochemistry & Molecular Biology ; Chemistry, Medicinal ; Food Science & Technology
WOS研究方向	Biochemistry & Molecular Biology ; Pharmacology & Pharmacy ; Food Science & Technology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/395327
推荐引用方式 GB/T 7714	Sfar, Manel,Souid, Ghada,Alminderej, Fahad M. M.,et al. Structural Characterization of Polysaccharides from Coriandrum sativum Seeds: Hepatoprotective Effect against Cadmium Toxicity In Vivo[J],2023,12(2).
APA	Sfar, Manel.,Souid, Ghada.,Alminderej, Fahad M. M..,Mzoughi, Zeineb.,El-Ghoul, Yassine.,...&Majdoub, Hatem.(2023).Structural Characterization of Polysaccharides from Coriandrum sativum Seeds: Hepatoprotective Effect against Cadmium Toxicity In Vivo.ANTIOXIDANTS,12(2).
MLA	Sfar, Manel,et al."Structural Characterization of Polysaccharides from Coriandrum sativum Seeds: Hepatoprotective Effect against Cadmium Toxicity In Vivo".ANTIOXIDANTS 12.2(2023).