干旱区生态环境知识资源中心(Arid): Validity Assessment of an Automated Brain Morphometry Tool for Patients with De Novo Memory Symptoms

Arid

DOI	10.3174/ajnr.A7790
	Validity Assessment of an Automated Brain Morphometry Tool for Patients with De Novo Memory Symptoms
	Rahmani, F.; Jindal, S.; Raji, C. A.; Wang, W.; Nazeri, A.; Perez-Carrillo, G. G.; Miller-Thomas, M. M.; Graner, P.; Marechal, B.; Shah, A.; Zimmermann, M.; Chen, C. D.; Keefe, S.; LaMontagne, P.; Benzinger, T. L. S.
通讯作者	Benzinger, TLS
来源期刊	AMERICAN JOURNAL OF NEURORADIOLOGY
ISSN	0195-6108
EISSN	1936-959X
出版年	2023
卷号	44 期号:3 页码:261-267
英文摘要	BACKGROUND AND PURPOSE: Automated volumetric analysis of structural MR imaging allows quantitative assessment of brain atrophy in neurodegenerative disorders. We compared the brain segmentation performance of the AI-Rad Companion brain MR imaging software against an in-house FreeSurfer 7.1.1/Individual Longitudinal Participant pipeline. MATERIALS AND METHODS: T1-weighted images of 45 participants with de novo memory symptoms were selected from the OASIS-4 database and analyzed through the AI-Rad Companion brain MR imaging tool and the FreeSurfer 7.1.1/Individual Longitudinal Participant pipeline. Correlation, agreement, and consistency between the 2 tools were compared among the absolute, normalized, and standardized volumes. Final reports generated by each tool were used to compare the rates of detection of abnormality and the compatibility of radiologic impressions made using each tool, compared with the clinical diagnoses. RESULTS: We observed strong correlation, moderate consistency, and poor agreement between absolute volumes of the main cortical lobes and subcortical structures measured by the AI-Rad Companion brain MR imaging tool compared with FreeSurfer. The strength of the correlations increased after normalizing the measurements to the total intracranial volume. Standardized measurements differed significantly between the 2 tools, likely owing to differences in the normative data sets used to calibrate each tool. When considering the FreeSurfer 7.1.1/Individual Longitudinal Participant pipeline as a reference standard, the AI-Rad Companion brain MR imaging tool had a specificity of 90.6%-100% and a sensitivity of 64.3%-100% in detecting volumetric abnormalities. There was no difference between the rate of compatibility of radiologic and clinical impressions when using the 2 tools. CONCLUSIONS: The AI-Rad Companion brain MR imaging tool reliably detects atrophy in cortical and subcortical regions implicated in the differential diagnosis of dementia.
类型	Article
语种	英语
开放获取类型	Green Published
收录类别	SCI-E
WOS记录号	WOS:000935465400001
WOS关键词	SURFACE-BASED ANALYSIS ; COGNITIVE IMPAIRMENT ; ALZHEIMERS-DISEASE ; DIAGNOSIS ; DEMENTIA ; GUIDELINES ; SCALE ; ADNI
WOS类目	Clinical Neurology ; Neuroimaging ; Radiology, Nuclear Medicine & Medical Imaging
WOS研究方向	Neurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/395276
推荐引用方式 GB/T 7714	Rahmani, F.,Jindal, S.,Raji, C. A.,et al. Validity Assessment of an Automated Brain Morphometry Tool for Patients with De Novo Memory Symptoms[J],2023,44(3):261-267.
APA	Rahmani, F..,Jindal, S..,Raji, C. A..,Wang, W..,Nazeri, A..,...&Benzinger, T. L. S..(2023).Validity Assessment of an Automated Brain Morphometry Tool for Patients with De Novo Memory Symptoms.AMERICAN JOURNAL OF NEURORADIOLOGY,44(3),261-267.
MLA	Rahmani, F.,et al."Validity Assessment of an Automated Brain Morphometry Tool for Patients with De Novo Memory Symptoms".AMERICAN JOURNAL OF NEURORADIOLOGY 44.3(2023):261-267.