干旱区生态环境知识资源中心(Arid): Should Cognitive Screening Tests Be Corrected for Age and Education? Insights From a Causal Perspective

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DOI	10.1093/aje/kwac159
	Should Cognitive Screening Tests Be Corrected for Age and Education? Insights From a Causal Perspective
	Piccininni, Marco; Rohmann, Jessica L.; Wechsung, Maximilian; Logroscino, Giancarlo; Kurth, Tobias
通讯作者	Piccininni, M
来源期刊	AMERICAN JOURNAL OF EPIDEMIOLOGY
ISSN	0002-9262
EISSN	1476-6256
出版年	2023
卷号	192 期号:1 页码:93-101
英文摘要	Cognitive screening tests such as the Mini-Mental State Examination are widely used in clinical routine to predict cognitive impairment. The raw test scores are often corrected for age and education, although documented poorer discrimination performance of corrected scores has challenged this practice. Nonetheless, test correction persists, perhaps due to the seemingly counterintuitive nature of the underlying problem. We used a causal framework to inform the long-standing debate from a more intuitive angle. We illustrate and quantify the consequences of applying the age-education correction of cognitive tests on discrimination performance. In an effort to bridge theory and practical implementation, we computed differences in discrimination performance under plausible causal scenarios using Open Access Series of Imaging Studies (OASIS)-1 data. We show that when age and education are causal risk factors for cognitive impairment and independently also affect the test score, correcting test scores for age and education removes meaningful information, thereby diminishing discrimination performance.
英文关键词	age-education test correction causal models cognitive impairment cognitive screening test directed acyclic graphs
类型	Article
语种	英语
开放获取类型	Green Published
收录类别	SCI-E
WOS记录号	WOS:000874847300001
WOS关键词	MENTAL-STATE-EXAMINATION ; IMPAIRMENT ; DEMENTIA ; DIAGNOSIS ; NORMS
WOS类目	Public, Environmental & Occupational Health
WOS研究方向	Public, Environmental & Occupational Health
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/395274
推荐引用方式 GB/T 7714	Piccininni, Marco,Rohmann, Jessica L.,Wechsung, Maximilian,et al. Should Cognitive Screening Tests Be Corrected for Age and Education? Insights From a Causal Perspective[J],2023,192(1):93-101.
APA	Piccininni, Marco,Rohmann, Jessica L.,Wechsung, Maximilian,Logroscino, Giancarlo,&Kurth, Tobias.(2023).Should Cognitive Screening Tests Be Corrected for Age and Education? Insights From a Causal Perspective.AMERICAN JOURNAL OF EPIDEMIOLOGY,192(1),93-101.
MLA	Piccininni, Marco,et al."Should Cognitive Screening Tests Be Corrected for Age and Education? Insights From a Causal Perspective".AMERICAN JOURNAL OF EPIDEMIOLOGY 192.1(2023):93-101.