干旱区生态环境知识资源中心(Arid): Annual Change in Fungal Concentrations and Allergic Sensitization Rates to Alternaria and Cladosporium in Korea During the Period 1998-2022

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DOI	10.4168/aair.2023.15.6.825
	Annual Change in Fungal Concentrations and Allergic Sensitization Rates to Alternaria and Cladosporium in Korea During the Period 1998-2022
	Choi, Young-Jin; Lee, Kyung-Suk; Jeong, Jin Hyeok; Kim, Kyunghoon; Yang, Seung; Na, Jae Yoon; Hwang, Jae Kyoon; Choe, Yunsoo; Kim, Kyu Rang; Han, Mae-Ja; Lee, Yung-Seop; Oh, Jae-Won
通讯作者	Oh, JW
来源期刊	ALLERGY ASTHMA & IMMUNOLOGY RESEARCH
ISSN	2092-7355
EISSN	2092-7363
出版年	2023
卷号	15 期号:6 页码:825-836
英文摘要	Purpose: Atmospheric fungi are associated with respiratory allergies in humans, and some fungal spores can cause allergic diseases. Environmental and biological factors influence the concentrations of atmospheric spores. In this study, we evaluated the climate change-induced annual variations in fungal spore concentrations and allergic sensitization rates in the Seoul Metropolitan Area over a period of 25 years.Methods: Fungal spores and pollen were obtained from Hanyang University Seoul and Guri Hospitals; they were identified and counted for 25 years (1998-2022). The study participants included patients who underwent tests for allergic diseases in both hospitals. Their allergenic sensitization rates were determined via allergic skin prick and serum tests, after which their sensitization rates to allergenic fungi and pollens were calculated. The daily climatic variables were obtained from the Korea Meteorological Administration.Results: The total annual atmospheric fungal concentrations decreased in both areas during the period. Simultaneously, we recruited 21,394 patients with allergies (asthma, 1,550; allergic rhinitis, 5,983; and atopic dermatitis, 5,422) from Seoul and Guri Hospitals for allergenic fungal sensitization evaluations over the period. The allergenic fungal sensitization rates decreased annually in both areas over that time `+(Alternaria [3.5%] and Cladosporium [4.4%] in 1998; Alternaria [0.2%] and Cladosporium [0.2%] in 2022). In contrast, the annual pollen concentrations increased with the sensitization rates to pollen in children.Conclusions: The atmospheric fungal concentrations decreased annually, with allergic sensitization rate decreasing over the period of 25 years. Allergenic fungal sporulation could decrease with climate changes, such as desertification and drought. Extended monitoring periods and further large-scale studies are required to confirm the causality and to evaluate the impact of climate change.
英文关键词	Fungal spores mold pollen pollen allergy climate change allergic disease skin prick test Alternaria Cladosporium
类型	Article
语种	英语
开放获取类型	gold, Green Published
收录类别	SCI-E
WOS记录号	WOS:001106888000009
WOS关键词	SPORE CONCENTRATIONS ; AIRBORNE ALTERNARIA ; MOLD ALLERGENS ; ASTHMA ; RHINITIS ; CHILDREN ; DENMARK
WOS类目	Allergy ; Immunology
WOS研究方向	Allergy ; Immunology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/395271
推荐引用方式 GB/T 7714	Choi, Young-Jin,Lee, Kyung-Suk,Jeong, Jin Hyeok,et al. Annual Change in Fungal Concentrations and Allergic Sensitization Rates to Alternaria and Cladosporium in Korea During the Period 1998-2022[J],2023,15(6):825-836.
APA	Choi, Young-Jin.,Lee, Kyung-Suk.,Jeong, Jin Hyeok.,Kim, Kyunghoon.,Yang, Seung.,...&Oh, Jae-Won.(2023).Annual Change in Fungal Concentrations and Allergic Sensitization Rates to Alternaria and Cladosporium in Korea During the Period 1998-2022.ALLERGY ASTHMA & IMMUNOLOGY RESEARCH,15(6),825-836.
MLA	Choi, Young-Jin,et al."Annual Change in Fungal Concentrations and Allergic Sensitization Rates to Alternaria and Cladosporium in Korea During the Period 1998-2022".ALLERGY ASTHMA & IMMUNOLOGY RESEARCH 15.6(2023):825-836.