干旱区生态环境知识资源中心(Arid): Crimean-Congo Hemorrhagic Fever Virus Survey in Humans, Ticks, and Livestock in Agnam (Northeastern Senegal) from February 2021 to March 2022

Arid

DOI	10.3390/tropicalmed7100324
	Crimean-Congo Hemorrhagic Fever Virus Survey in Humans, Ticks, and Livestock in Agnam (Northeastern Senegal) from February 2021 to March 2022
	Mhamadi, Moufid; Badji, Aminata; Dieng, Idrissa; Gaye, Alioune; Ndiaye, El Hadji; Ndiaye, Mignane; Mhamadi, Moundhir; Toure, Cheikh Talibouya; Mbaye, Mouhamed Rassoul; Barry, Mamadou Aliou; Ndiaye, Oumar; Faye, Babacar; Ba, Fatimata Amadou; Diop, Boly; Ndiaye, Mamadou; Fall, Mathioro; Sagne, Samba Niang; Fall, Gamou; Loucoubar, Cheikh; Fausther-Bovendo, Hugues; Sall, Amadou Alpha; Kobinger, Gary; Faye, Ousmane; Diallo, Mawlouth; Faye, Oumar
通讯作者	Faye, O
来源期刊	TROPICAL MEDICINE AND INFECTIOUS DISEASE
EISSN	2414-6366
出版年	2022
卷号	7 期号:10
英文摘要	Crimean-Congo hemorrhagic fever virus (CCHFV) is widespread in Asia, Europe, and Africa. In Senegal, sporadic cases of CCHFV have been reported since 1960. Bordering Mauritania in northeastern Senegal, Agnam is an arid area in the region of Matam where CCHFV is endemic, which harbors a pastoralist community. Given the drought conditions of Agnam, inhabitants are in constant movement with their animals in search of pasture, which brings them into contact with pathogens such as arboviruses. To identify CCHFV in this area, we established a One Health site in order to analyze animal livestock, ticks and human samples collected over a one-year period by qRT-PCR and ELISA. Our analysis showed one (1/364) patient carried anti-CCHFV IgM and thirty-seven carried anti-CCHFV IgG (37/364). In livestock, anti-CCHFV IgG was detected in 13 (38.24%) of 34 sentinel sheep. The risk of CCHFV infection increased significatively with age in humans (p-value = 0.00117) and sheep (p-value = 1.18 x 10(-11)). Additional risk factors for CCHFV infection in sheep were dry seasons (p-value = 0.004) and time of exposure (p-value = 0.007). Furthermore, we detected a total of three samples with CCHFV RNA within Rhipicephalus evertsi evertsi and Rhipicephalus guilhoni tick species. Our results highlighted the usefulness of a One Health survey of CCHFV in pastoral communities at risk of arboviruses.
英文关键词	CCHF prevalence human sheep tick
类型	Article
语种	英语
开放获取类型	gold, Green Published
收录类别	SCI-E
WOS记录号	WOS:000873416800001
WOS关键词	RIFT-VALLEY FEVER ; EXPERIMENTAL TRANSMISSION ; EPIDEMIOLOGY ; DIAGNOSIS ; IXODIDAE
WOS类目	Infectious Diseases ; Parasitology ; Tropical Medicine
WOS研究方向	Infectious Diseases ; Parasitology ; Tropical Medicine
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/394747
推荐引用方式 GB/T 7714	Mhamadi, Moufid,Badji, Aminata,Dieng, Idrissa,et al. Crimean-Congo Hemorrhagic Fever Virus Survey in Humans, Ticks, and Livestock in Agnam (Northeastern Senegal) from February 2021 to March 2022[J],2022,7(10).
APA	Mhamadi, Moufid.,Badji, Aminata.,Dieng, Idrissa.,Gaye, Alioune.,Ndiaye, El Hadji.,...&Faye, Oumar.(2022).Crimean-Congo Hemorrhagic Fever Virus Survey in Humans, Ticks, and Livestock in Agnam (Northeastern Senegal) from February 2021 to March 2022.TROPICAL MEDICINE AND INFECTIOUS DISEASE,7(10).
MLA	Mhamadi, Moufid,et al."Crimean-Congo Hemorrhagic Fever Virus Survey in Humans, Ticks, and Livestock in Agnam (Northeastern Senegal) from February 2021 to March 2022".TROPICAL MEDICINE AND INFECTIOUS DISEASE 7.10(2022).