干旱区生态环境知识资源中心(Arid): HPLC-DAD phenolic screening and in vitro assessment of antimicrobial, antioxidant and anti-inflammatory activities of Tanteboucht dates

Arid

DOI	10.1039/d2ra01630c
	HPLC-DAD phenolic screening and in vitro assessment of antimicrobial, antioxidant and anti-inflammatory activities of Tanteboucht dates
	Dassamiour, Saliha; Meguellati, Selsabil; Lamraoui, Hdouda; Bensaad, Mohamed Sabri; Sami, Rokayya; Alshehry, Garsa; Althubaiti, Eman Hillal; Al-Meshal, Areej Suliman
通讯作者	Sami, R
来源期刊	RSC ADVANCES
EISSN	2046-2069
出版年	2022
卷号	12 期号:21 页码:13330-13338
英文摘要	The date palm (Phoenix dactylifera L.) is one of the most important crops in arid and semi-arid zones. Date fruit occupies a good place in traditional medicine among the Saharan residents, due to its therapeutic virtues; although there may be several therapeutic virtues yet to be discovered. The aim of this study was to investigate the phytochemical and pharmacological properties of the hexanic (EHx), chloroformic (ECh), ethyl acetate (EAc) and aqueous (EAq) extracts of Tanteboucht pulp. The phytochemical characterization and estimation of phenolic compounds were done based on an HPLC-DAD approach. The antioxidant activity was evaluated by a DPPH scavenging effect test. The sensitivity of 7 bacterial strains and Candida albicans to Tanteboucht extracts was tested using the diffusion disc on agar medium method. The membrane stabilization test was used to determine the in vitro anti-inflammatory effect of the fruit extracts. Fourteen phenolic compounds were detected in organic extracts and EAc was the richest followed by ECh and finally EHx which was very poor in these molecules. All extracts showed antioxidant, anti-inflammatory and antimicrobial properties which differ in rate. Indeed, ECh had the greatest scavenging effect on DPPH, followed by EAc and then EAq. EAc was the most potent inhibitor of microbial strains. EAc and ECh were more efficient at membrane stabilization followed by EAq and the three extracts had more anti-inflammatory capacity than the positive control acetyl salicylic acid. The obtained considerable activities were significantly correlated with flavonoid and tannin contents in the extracts.
类型	Article
语种	英语
开放获取类型	gold, Green Published
收录类别	SCI-E
WOS记录号	WOS:000790371600001
WOS关键词	MEMBRANE STABILIZING ACTIVITY ; ANTIBACTERIAL ACTIVITY ; QUERCETIN ; VARIETIES ; EXTRACTS ; DISEASE ; LIVER ; RUTIN ; ACID
WOS类目	Chemistry, Multidisciplinary
WOS研究方向	Chemistry
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/394326
推荐引用方式 GB/T 7714	Dassamiour, Saliha,Meguellati, Selsabil,Lamraoui, Hdouda,et al. HPLC-DAD phenolic screening and in vitro assessment of antimicrobial, antioxidant and anti-inflammatory activities of Tanteboucht dates[J],2022,12(21):13330-13338.
APA	Dassamiour, Saliha.,Meguellati, Selsabil.,Lamraoui, Hdouda.,Bensaad, Mohamed Sabri.,Sami, Rokayya.,...&Al-Meshal, Areej Suliman.(2022).HPLC-DAD phenolic screening and in vitro assessment of antimicrobial, antioxidant and anti-inflammatory activities of Tanteboucht dates.RSC ADVANCES,12(21),13330-13338.
MLA	Dassamiour, Saliha,et al."HPLC-DAD phenolic screening and in vitro assessment of antimicrobial, antioxidant and anti-inflammatory activities of Tanteboucht dates".RSC ADVANCES 12.21(2022):13330-13338.