干旱区生态环境知识资源中心(Arid): Estimating the burden of mycetoma in Sudan for the period 1991-2018 using a model-based geostatistical approach

Arid

DOI	10.1371/journal.pntd.0010795
	Estimating the burden of mycetoma in Sudan for the period 1991-2018 using a model-based geostatistical approach
	Hassan, Rowa; Cano, Jorge; Fronterre, Claudio; Bakhiet, Sahar; Fahal, Ahmed; Deribe, Kebede; Newport, Melanie
通讯作者	Hassan, R
来源期刊	PLOS NEGLECTED TROPICAL DISEASES
ISSN	1935-2735
出版年	2022
卷号	16 期号:10
英文摘要	Mycetoma is widespread in tropical and subtropical regions favouring arid areas with low humidity and a short rainy season. Sudan is one of the highly endemic countries for mycetoma. Estimating the population at risk and the number of cases is critical for delivering targeted and equitable prevention and treatment services. In this study, we have combined a large dataset of mycetoma cases recorded by the Mycetoma Research Centre (MRC) in Sudan over 28 years (1991-2018) with a collection of environmental and water and hygiene-related datasets in a geostatistical framework to produce estimates of the disease burden across the country. We developed geostatistical models to predict the number of cases of actinomycetoma and eumycetoma in areas considered environmentally suitable for the two mycetoma forms. Then used the raster dataset (gridded map) with the population estimates for 2020 to compute the potentially affected population since 1991. The geostatistical models confirmed this heterogeneous and distinct distribution of the estimated cases of eumycetoma and actinomycetoma across Sudan. For eumycetoma, these higher-risk areas were smaller and scattered across Al Jazirah, Khartoum, White Nile and Sennar states, while for actinomycetoma a higher risk for infection is shown across the rural districts of North and West Kurdufan. Nationally, we estimated 63,825 people (95%CI: 13,693 to 197,369) to have been suffering from mycetoma since 1991 in Sudan,51,541 people (95% CI: 9,893-166,073) with eumycetoma and 12,284 people (95%CI: 3,800-31,296) with actinomycetoma. In conclusion, the risk of mycetoma in Sudan is particularly high in certain restricted areas, but cases are ubiquitous across all states. Both prevention and treatment services are required to address the burden. Such work provides a guide for future control and prevention programs for mycetoma, highly endemic areas are clearly targeted, and resources are directed to areas with high demand.
类型	Article
语种	英语
开放获取类型	Green Published, gold
收录类别	SCI-E
WOS记录号	WOS:000922587500031
WOS关键词	HUMAN EUMYCETOMA ; EPIDEMIOLOGY ; AGENT
WOS类目	Infectious Diseases ; Parasitology ; Tropical Medicine
WOS研究方向	Infectious Diseases ; Parasitology ; Tropical Medicine
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/394020
推荐引用方式 GB/T 7714	Hassan, Rowa,Cano, Jorge,Fronterre, Claudio,et al. Estimating the burden of mycetoma in Sudan for the period 1991-2018 using a model-based geostatistical approach[J],2022,16(10).
APA	Hassan, Rowa.,Cano, Jorge.,Fronterre, Claudio.,Bakhiet, Sahar.,Fahal, Ahmed.,...&Newport, Melanie.(2022).Estimating the burden of mycetoma in Sudan for the period 1991-2018 using a model-based geostatistical approach.PLOS NEGLECTED TROPICAL DISEASES,16(10).
MLA	Hassan, Rowa,et al."Estimating the burden of mycetoma in Sudan for the period 1991-2018 using a model-based geostatistical approach".PLOS NEGLECTED TROPICAL DISEASES 16.10(2022).