干旱区生态环境知识资源中心(Arid): Internet-Delivered Cognitive Behavioral Therapy for Generalized Anxiety Disorder in Nationwide Routine Care: Effectiveness Study

Arid

DOI	10.2196/29384
	Internet-Delivered Cognitive Behavioral Therapy for Generalized Anxiety Disorder in Nationwide Routine Care: Effectiveness Study
	Ritola, Ville; Lipsanen, Jari Olavi; Pihlaja, Satu; Gummerus, Eero-Matti; Stenberg, Jan-Henry; Saarni, Suoma; Joffe, Grigori
通讯作者	Joffe, G
来源期刊	JOURNAL OF MEDICAL INTERNET RESEARCH
ISSN	1438-8871
出版年	2022
卷号	24 期号:3
英文摘要	Background: Therapist-supported, internet-delivered cognitive behavioral therapy (iCBT) is efficacious for generalized anxiety disorder (GAD), but few studies are yet to report its effectiveness in routine care. Objective: In this study, we aim to examine whether a new 12-session iCBT program for GAD is effective in nationwide routine care. Methods: We administered a specialized, clinic-delivered, therapist-supported iCBT for GAD in 1099 physician-referred patients. The program was free of charge for patients, and the completion time was not predetermined. We measured symptoms with web-based questionnaires The primary measure of anxiety was the GAD 7-item scale (GAD-7); secondary measures were, for pathological worry, the Penn State Worry Questionnaire and, for anxiety and impairment, the Overall Anxiety Severity and Impairment Scale. Results: Patients completed a mean 7.8 (SD 4.2; 65.1%) of 12 sessions, and 44.1% (485/1099) of patients completed all sessions. The effect size in the whole sample for GAD-7 was large (Cohen d=0.97, 95% CI 0.88-1.06). For completers, effect sizes were very large (Cohen d=1.34, 95% CI 1.25-1.53 for GAD-7; Cohen d= 1.14, 95% CI 1.00-1.27 for Penn State Worry Questionnaire; and Cohen d=1.23, 95% CI 1.09-1.37 for Overall Anxiety Severity and Impairment Scale). Noncompleters also benefited from the treatment. Greater symptomatic GAD-7-measured relief was associated with more completed sessions, older age, and being referred from private or occupational care. Of the 894 patients with a baseline GAD-7 score >= 10, approximately 421 (47.1%) achieved reliable recovery. Conclusions: This nationwide, free-of-charge, therapist-supported HUS Helsinki University Hospital-iCBT for GAD was effective in routine care, but further research must establish effectiveness against other treatments and optimize the design of iCBT for GAD for different patient groups and individual patients.
英文关键词	CBT iCBT cognitive behavioral therapy routine care generalized anxiety disorder internet web-based digital health mental health
类型	Article
语种	英语
开放获取类型	Green Published, gold
收录类别	SCI-E ; SSCI
WOS记录号	WOS:000789288600001
WOS关键词	STATE WORRY QUESTIONNAIRE ; IMPAIRMENT SCALE OASIS ; PSYCHOMETRIC PROPERTIES ; METAANALYSIS ; DEPRESSION ; SEVERITY ; VALIDATION ; PSYCHOTHERAPY ; VALIDITY ; VERSION
WOS类目	Health Care Sciences & Services ; Medical Informatics
WOS研究方向	Health Care Sciences & Services ; Medical Informatics
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/393549
推荐引用方式 GB/T 7714	Ritola, Ville,Lipsanen, Jari Olavi,Pihlaja, Satu,et al. Internet-Delivered Cognitive Behavioral Therapy for Generalized Anxiety Disorder in Nationwide Routine Care: Effectiveness Study[J],2022,24(3).
APA	Ritola, Ville.,Lipsanen, Jari Olavi.,Pihlaja, Satu.,Gummerus, Eero-Matti.,Stenberg, Jan-Henry.,...&Joffe, Grigori.(2022).Internet-Delivered Cognitive Behavioral Therapy for Generalized Anxiety Disorder in Nationwide Routine Care: Effectiveness Study.JOURNAL OF MEDICAL INTERNET RESEARCH,24(3).
MLA	Ritola, Ville,et al."Internet-Delivered Cognitive Behavioral Therapy for Generalized Anxiety Disorder in Nationwide Routine Care: Effectiveness Study".JOURNAL OF MEDICAL INTERNET RESEARCH 24.3(2022).