干旱区生态环境知识资源中心(Arid): Chemical Composition, Antibacterial, Antifungal and Antidiabetic Activities of Ethanolic Extracts of Opuntia dillenii Fruits Collected from Morocco

Arid

DOI	10.1155/2022/9471239
	Chemical Composition, Antibacterial, Antifungal and Antidiabetic Activities of Ethanolic Extracts of Opuntia dillenii Fruits Collected from Morocco
	Loukili, El Hassania; Bouchal, Btissam; Bouhrim, Mohamed; Abrigach, Farid; Genva, Manon; Zidi, Kahina; Bnouham, Mohamed; Bellaoui, Mohammed; Hammouti, Belkheir; Addi, Mohamed; Ramdani, Mohammed; Fauconnier, Marie-Laure
通讯作者	Addi, M
来源期刊	JOURNAL OF FOOD QUALITY
ISSN	0146-9428
EISSN	1745-4557
出版年	2022
卷号	2022
英文摘要	Opuntia dillenii (Ker Gawl.) Haw. belongs to the Cactaceae family and is native to the arid and semi-arid regions of Mexico and the southern United States. O. dillenii are now used as medicinal plants in various countries. In this study, we investigated the chemical composition of ethanolic extracts obtained from seeds, juice, and peel of O. dillenii fruits collected from Morocco, and we evaluated their antibacterial, antifungal, and antidiabetic activities. Phytochemical screening revealed high quantities of polyphenols (193.73 +/- 81.44 to 341.12 +/- 78.90 gallic acid eq [g/100 g dry weight]) in the extracts. The major phenolic compounds determined by HPLC were gallic acid, vanillic acid, and syringic acid. Regarding flavonoids, quercetin 3-O-beta-D-glucoside and kaempferol were the predominant molecules. Juice extracts showed weak to moderate antibacterial activity against the bacteria species Listeria monocytogenes, Escherichia coli, and Salmonella braenderup. All tested extracts displayed a significant inhibitory effect on alpha-glucosidase and alpha-amylase activities in vitro, with the peel extracts showing the greatest inhibitory effects. Together, these findings suggest that O. dillenii fruits are a promising source for the isolation of novel compounds with antibacterial or antidiabetic activities. For the most abundant phytochemicals identified in O. dillenii peel ethanolic extract, molecular docking simulations against human pancreatic alpha-amylase enzyme were performed. These indicated the presence of bioactive compounds in the extract with a better potential to decrease the enzyme activity than the commercial drug acarbose.
类型	Article
语种	英语
开放获取类型	gold, Green Published
收录类别	SCI-E
WOS记录号	WOS:000880424000001
WOS关键词	PANCREATIC ALPHA-AMYLASE ; IN-VITRO ; ANTIOXIDANT CAPACITY ; SEED OIL ; GLUCOSIDASE ; INHIBITION ; PLANT ; CATECHIN ; COMPONENTS ; FLAVONOIDS
WOS类目	Food Science & Technology
WOS研究方向	Food Science & Technology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/393437
推荐引用方式 GB/T 7714	Loukili, El Hassania,Bouchal, Btissam,Bouhrim, Mohamed,et al. Chemical Composition, Antibacterial, Antifungal and Antidiabetic Activities of Ethanolic Extracts of Opuntia dillenii Fruits Collected from Morocco[J],2022,2022.
APA	Loukili, El Hassania.,Bouchal, Btissam.,Bouhrim, Mohamed.,Abrigach, Farid.,Genva, Manon.,...&Fauconnier, Marie-Laure.(2022).Chemical Composition, Antibacterial, Antifungal and Antidiabetic Activities of Ethanolic Extracts of Opuntia dillenii Fruits Collected from Morocco.JOURNAL OF FOOD QUALITY,2022.
MLA	Loukili, El Hassania,et al."Chemical Composition, Antibacterial, Antifungal and Antidiabetic Activities of Ethanolic Extracts of Opuntia dillenii Fruits Collected from Morocco".JOURNAL OF FOOD QUALITY 2022(2022).